The bilingual teaching must face some innovations and reformations in the contents and methods to acquire some satisfactory outcome.The article discusses some questions of bilingual teaching in paediatrics including the shortage of teachers,the interest deficiency of students,the lack of suitable teaching materials and inferior learning environment,and then provides some useful advice for the innovations of bilingual teaching.

A discussion of the connotation and key issues of the new normal in the healthcare sector,with an introduction to the new normal.The furthering reform is unveiling roadblocks in the healthcare system.For example,human resources available can hardly support development of the sector, and revenue growth of tertiary hospitals in the cities will decline,while county hospitals will be further challenged by debt crisis.In the meantime of steady elevation of medical capabilities in both urban and rural areas,the gap between the two will be maintained for a while.The authors predict that the sector will be faced with restructuring essential medicine system,grading diagnosis and treatment practice,rising risks for health insurance,and growing market shares of commercial health insurance and private capital, as well as fiercer competitions to challenge public hospitals.

Aim To observe the effects of Ginsenoside on left ventricular remodeling after pressure-overload hypertrophy in rats.Methods After stenosis of the ascending aortic artery,20 survived female Wistar rats were randomly assigned to two groups:hypertrophy control(n=10)and Ginsenoside(100 mg?kg?d-1,n=10);sham operated rats(n=10)were selected randomly as nonstenosis control.Four weeks after the operation,the LVPW,IVS and LVDD of each rat were detected by echocardiogram.Myocardial cell and interstitial tissue were observed by immunofluorescence double staining.Results Compared with those in hypertrophy group,the LVPW and IVS in Ginsenoside group were all significantly decreased(P

0.05).Conclusions The chemotherapeutic embedding radioactive particle 125Ⅰ combined with GP is safe,feasible,and effective to the therapy of senile-inoperable NSCLC.

Female ; Gram-Negative Bacteria ; Humans ; Leukemia ; complications ; Male ; Middle Aged ; Skin Diseases, Bacterial ; microbiology ; Soft Tissue Infections ; microbiology

BACKGROUND: Necrosis of femoral head induced by hormone is the iatrogenic disorder. It is doubt whether such problem is improved or not by increasing blood-flow volume in the local necrosis tissues.OBJECTIVE: To observe the effects of electric acupuncture on blood-flow volume in local tissues of femoral head so as to understand the mechanism of acupuncture on hormonal necrosis of femoral head.DESIGN: Randomized controlled study in which the experimental animals were taken as the objects.SETTING: Department of integrated traditional chinese and western medicine in a college of traditional chinese medicine.MATERIALS: The experiment was performed from May 2002 to June 2003in Animal Experimental Room of Clinical Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Anhui College of Traditional Chinese Medicine. Thirty female and male(half-half) New Zealand white rabbits were employed, in clean grade, which were randomized into blank control, model group and treatment of electric acupuncture group.METHODS: The model of hormonal necrosis of femoral head in rabbits was prepared. In the treatment group, PCE-88A type controlled electric acupuncture apparatus developed by Institute of Acupuncture and Meridians and Collaterials in Anhui College of Traditional Chinese Medicine was applied on Huantiao(GB 30) and Biguan(ST 31) . No any treatment was applied in the model and blank groups.MAIN OUTCOME MEAURES: The curve of blood-flow volume in local necrosis tissues at the moment of acupuncture and 2 weeks after treatment.RESULTS: The blood-flow volume in local necrosis tissues at the moment of acupuncture in the treatment group(0.50 ±0.08) mL/g per minute was reduced significantly compared with that of blank control group[(8.63± 0. 83) mL/g per minute] and the model group[ (4.30 ±0. 89) mL/g per minute], indicating significant difference ( P ＜ 0.01). The blood-flow volume in local necrosis tissues 2 weeks after treatment[ (6. 19 ± 0.61) mL/g per minute] was remarkably increased compared with the blank control [ (8.33 ± 0.65) mL/g per minute] and the model group[ (4.44 ± 0. 72) mL/g per minute], indicating significant difference( P ＜ 0.01).CONCLUSION: Electric acupuncture can improve local blood supply in hormonal necrosis of femoral head immediately, which is probably related to the regulation in the net of nerve-endocrine-immunity.

Adult ; Aged ; Benzamides ; therapeutic use ; Case-Control Studies ; Female ; Humans ; Imatinib Mesylate ; Immunoglobulins ; metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; drug therapy ; immunology ; Male ; Middle Aged ; Piperazines ; therapeutic use ; Pyrimidines ; therapeutic use ; T-Lymphocyte Subsets

Amoxicillin ; adverse effects ; Anti-Bacterial Agents ; adverse effects ; Child ; Humans ; Male ; Renal Insufficiency ; chemically induced

Materials Testing ; instrumentation ; Plastics ; chemistry ; Stress, Mechanical ; Temperature ; Water

Objective To observe the effect of vitamin A(VitA) on T help 17(Th17) and regulatory T cells (Treg) in the peripheral blood in children with asthma and their dose effect relationship,and to investigate the immunoregulation mechanism of VitA.Methods Twenty children with asthma (asthma group) and 16 healthy children (healthy control group) were selected.Peripheral blood mononuclear cells(PBMC) were isolated from venous blood by density gradient centrifugation in the aseptic condition.Different concentrations of VitA [0.0μmol/L (blank control),0.5μmol/L,1.0μmol/L,2.0μmol/L] were added into the cultures in the asthma group.The healthy control group were not interfered with VitA.The supernatant was collected after 72 h.The levels of interleukin 17 (IL-17),interleukin 10(IL-10) and transforming growth factor-β1 (TGF-β1) in the supernatant were determined by enzyme-linked immunosorbent assay.Results (1) IL-17 levels produced by PBMC in the asthma group were significantly higher than those in the healthy control group [(960.53±75.59) ng/L vs (425.07±70.71) ng/L,P＜0.01],and the levels of IL-10 and TGF-β1 were significantly lower than those in the healthy control group [(53.13±6.94)ng/L vs (84.41±6.02) ng/L,(304.51±51.52) ng/L vs (489.45±73.68) ng/L,all P＜0.01].(2) IL-17 levels produced by PBMC in the 0.5μmol/L,1.0μmol/L and 2.0μmol/L VitA concentration of the asthma group [(588.95±44.18)ng/L,(573.13±27.43) ng/L,(686.71±38.98) ng/L] were significantly lower than those in the blank control group[(960.53±75.59) ng/L,all P＜0.01],and IL-17 levels in the 2.0 μmol/L VitA concentration were significantly higher than those in 0.5μmol/L and 1.0μmol/L concentration groop (P＜0.01).(3) IL-10 levels produced by PBMC in the 0.5μmol/L,1.0μmol/L and 2.0μmol/L VitA concentration of the asthma group [(105.35±10.79) ng/L,(111.21±16.11) ng/L,(81.09±6.05) ng/L] were significantly higher than those in the blank control group[(53.13±6.94) ng/L,all P＜0.01],TGF-β1 levels produced by PBMC in the 0.5μmol/L,1.0μmol/L and 2.0μmol/L VitA concentration of the asthma group[(933.01±73.98) ng/L,(1223.31±105.99)ng/L,(776.98±145.44) ng/L] were significantly higher than that in blank control group[(304.51±51.52) ng/L,all P＜0.01],and the levels of IL-10 and TGF-β1 in the 0.5 μmol/L and 1.0μmol/L concentration group were significantly higher than those in the 2.0μmol/L concentration group(all P＜0.01).The level of TGF-β1 in the 1.0μmol/L concentration group were significantly higher than that in the 0.5μmol/L concentration group (P＜0.01).Conclusions The function of Th17 in children with asthma during asthma attack was enhanced,and the function of Treg cells was reduced.The balance disorder of the functions of Th17 and Treg cells occurred.VitA can reduce the function of Th17 in peripheral blood,and enhance the activity of Treg cells in the children with asthma.The physiological level of VitA has the best effect,if high VitA concentration is high its effect is significantly decreased.