1.Application of pre- hospital emergency care in children with febrile seizures and effect evaluation
Dongmei LI ; Kaizhu CHEN ; Jinsheng LIN ; Weisheng REN ; Chao BAI
Chinese Journal of Practical Nursing 2012;13(13):19-20
Objective To investigate the effect of pre- hospital emergency care programs in children with febrile seizures,in order to reduce damage by febrile seizures and obtain the best firstaid effect. Methods 112 cases of children with febrile seizures were treated in pediatric department of our hospital from April 2009 to February 2011.The parents of 75 children patients were given guidance of prehospital emergency care,they were set as the pre-hospital emergency care group.The other 37 cases were set as the non-pre-hospital emergency care group,routine emergency care was given until the medical personnel arrived at the spot.The conditions of aspiration,tongue bite injury,another episode of febrile seizures and brain damage were recorded in two groups of children. Results Only one case of aspiration and three cases of febrile seizures occurred in the pre-hospital emergency care group by misoperation of parents.Non brain damage and tongue bite injury occurred.The incidence rate of improper consequences was 5.3%in the pre-hospital emergency care group,lower than that of the non-pre-hospital emergency care group,51.4%. Conclusions To give pre-hospital emergency care guidance to parents of children patients by mobile phones before the health care workers reach the spot can significantly reduce accidental injury of children,stabilize the emotion of parents,decrease the impact of seizures on children,all the above has a positive effect on follow-up treatment.
2.Key points of ethical review for clinical trials of medical techniques
Caizhen BAI ; Wanquan ZHAO ; Peijuan REN ; Chen WANG ; Yangyun CHAO
Chinese Journal of Hospital Administration 2014;30(6):457-459
An introduction to the classified management of such trials and clinical application,documents submission for ethical review,operating procedures and review key points,as well as the problems found in the review.These efforts aim to provide guidance to the review of medical technique clinical trials,and to promote ethical supervision for new medical techniques.
3.Systemic blood pressure,intraocular pressure and primary open-glaucoma: A populationbased study in Shaanxi Province of China
Zhi-Lan, BAI ; Bai-Chao, REN ; Jian-Gang, YANG ; Yuan, HE ; Li, CHEN ; Nai-Xue, SUN
International Eye Science 2005;5(6):1122-1127
AIM :To investigate the association of primary open-glaucoma (POAG), intraocular pressure (IOP) and systemic blood pressure in a rural population aged 50 years old or above in Shaanxi Province, China.METHODS: In the population-based, cross-sectional study, 1 775 (83.53%) residents, aged 50 years old or above, from 3 counties of Shaanxi Province, China, undertook an interview with a standard questionnaire and a detailed eye examination, including logarithm of the minimum angle of resolution visual acuity, slit-lamp biomicroscopy, applanation tonometry and dilated fundus examination. Two blood pressure reading in the sitting position were taken. Gonioscopy was performed if a narrower peripheral anterior chamber (less than one fourth of the corneal thickness) was indicated. Automated visual field testing was performed by participants assessed to have suspicion of glaucomatous disc damage or if IOP was 22mmHg or higher.RESULTS: IOP significantly correlated with systemic blood pressure, and both IOP and systolic blood pressure increased significantly with increasing age. No association between POAG and hypertension was found. The frequency of POAG increased significantly with lower diastolic perfusion pressure.CONCLUSION: Data in our study are accordance with those reported in other population-based studies, and confirm that lower diastolic perfusion pressure is a significant risk factor for primary open angle glaucoma.
4.Epidemiological investigation on age-related macular degeneration in rural area of Shaanxi Province,China
Zhi-Lan, BAI ; Bai-Chao, REN ; Jian-Gang, YANG ; Yuan, HE ; Li, CHEN ; Nai-Xue, SUN
International Eye Science 2005;5(6):1114-1121
AIM: To assess the prevalence and risk factors for age-related macular degeneration (AMD) in a rural population in Shaanxi Province of China.METHODS: A total of 2 835 (81.00%) people aged 40 years old or more, from Fuping county, Jingbian county and Yang county of Shaanxi Province, China, underwent a comprehensive interview and a relative eye examination. The present of AMD was classified into neovascular AMD (NV) and pure geographic atrophy (GA) by using direct ophthalmoscopy for fundus examination according to International Classification System.RESULTS: The prevalence (95% CI) of AMD was 3.00% (2.42, 3.71) in this population, of which NV accounted for 1.45% (1.05, 1.98) and 1.55% (1.14, 2.10)for GA. The prevalence of AMD increased significantly with increasing age (P <0.001). AMD was present in 0.47% of participants aged 40 to 49 years, rising to 11.90% of participants older than 80 years, of which the corresponding data increased from 0.28% to 4.76% for NV and from 0.19% to 7.14% for GA. No significant difference was found in the prevalence of NA and GA between genders in this population. With multiple logistic analyses, apart from advancing age, only smoking was found to have a strong association with any type of AMD.CONCLUSION: The prevalence of AMD in the rural population of Shaanxi Province of China is lower than that reported from other population-based studies in different provinces of China, less than that reported in whites, more than that reported in blacks. Except increasing age, smoking is also a significant well-known risk factor for AMD.
5.Epidemiology of primary angle-closure glaucoma in a rural population in Shaanxi Province of China
Zhi-Lan, BAI ; Bai-Chao, REN ; Jian-Gang, YANG ; Yuan, HE ; Li, CHEN ; Nai-Xue, SUN
International Eye Science 2005;5(5):872-880
· AIM: To assess the prevalence and related risk factors for primary angle-closure glaucoma in a rural population for 40 years of age or older in Shaanxi Province.· METHODS: By using a stratified, cluster-based, random sampling technique, 8 500 persons of all ages were selected randomly, including 3 500 those aged 40 years or more, from the North, the South and the Middle of Shaanxi Province in Western China from July to December in 2003. All participants had an interview with a standard questionnaire and those questions related to glaucoma of previous diagnosis and treatment, family history and outbreak history. Then a detailed and relative eye examination was performed, including logarithm of the minimum angle of resolution visual acuity, external eye examination with slit-lamp biomicroscopy and fundus examination. The intraocular pressure was measured with Perkins applanation tonometry to those persons aged 50 years old or more and those with suspected increased IOP. A further examination was performed to those persons with suspicious glaucoma, including repeated tonometric examination, gonioscopy, dark room test, automated visual field testing, et al.·RESULTS: 6 815 of the eligible 8 500 persons of all ages were interviewed and examined from July to December in 2003, a response rate of 80.18%, including 2835 of the eligible 3 500 persons of 40 years old or more with a response rate of 81.00%. According to Van Herick method, the percentage of shallow peripheral anterior chamber was 13.6%, of which 10.4% was in grade 2, 3.0% in grade 1, and 0.2% in grade 0. In this rural population for 40 years of age or older 31 participants were found to have primary angle-closure glaucoma, with the prevalence of 1.09%. With multiple logistic analyses, the prevalence increased significantly with age (P=0.008), whereas no significant difference (Pgender=0.180, Peducation=0.199) was found in the rate with gender and education, although women and illiteracy seemed to be at increased risk of the disease (OR: 1.77, 95%CI,0.77-4.10; OR: 1.71, 95%CT, 0.76-3.87). Of 31 participants, 21 persons (67.74%) had not been previously diagnosed and treated. Of 10 participants previously diagnosed, 6 (60%) had been received peripheral iridectomy; nevertheless, no any other treatments were performed. 48.39% participants suffered from visual impairment in various degrees, of which the percentage of blindness in either eye accounted for 29.03%. Of those with primary angle-closure glaucoma, 22 persons (70.97%) were classified as having chronic from of the disease.· CONCLUSION: In this rural population in Shaanxi Province of China, the rate of occludable angles is 13.6%, more common than that reported previously in other Chinese populations. The prevalence of primary angle-closure glaucoma is close to that from other Asian populations, increasing with age. A majority of glaucoma was undiagnosed and untreated previously.
6.Epidemiology of primary open angle glaucoma in a rural population in Shaanxi Province of China
Zhi-Lan, BAI ; Bai-Chao, REN ; Yuan, HE ; Jian-Gang, YANG ; Li, CHEN ; Nai-Xue, SUN
International Eye Science 2005;5(5):864-871
· AIM: To assess the prevalence and related risk factors of primary open angle glaucoma (POAG) in a rural population in Shaanxi Province.· METHODS: By using a stratified, duster-based, random sampling technique, 8 500 persons of all ages were selected randomly, from the North, the South and the Middle of Shaanxi Province from July to December in 2003. All participants had an interview with a standard questionnaire and those questions related to glaucoma of previous diagnosis and treatment, family history and outbreak history. Then a detailed and relative eye examination was performed, including logarithm of the minimum angle of resolution visual acuity, external eye examination with slit-lamp biomicroscopy and fundus examination. The intraocular pressure was measured with Perkins applanation tonometry to those persons aged 50years old or more and those with suspected increased IOP. A further examination was performed to those persons with suspicious glaucoma, including repeated tonometric examination, gonioscopy, dark room test, automated visual field testing, et al.· RESULTS: 6 815 of the eligible 8 500 persons of all ages were interviewed and examined from July to December in 2003, a response rate of 80.18%. 9 participants were found to have POAG, with the prevalence of 0.13%, age ranging from 38 to 80 years (mean year:62.0). In those aged 30 years old or more, the prevalence of the disease was 0.23%, 0.28% and 0.39% for those more than 40 and 50 years old, respectively. The rate of suspicious POAG was 0.18% (12 cases) with age ranging from 35 to 77 years (mean year: 54.7). With multiple logistic analyses, the prevalence increased significantly with age (P=0.023). Other than increasing age, myopia was also a strong risk factor for POAG. Of 9participants with POAG, only 2 cases (22.22%) had been previously diagnosed. No one with POAG was received any treatment previously. 66.67% (6 cases) participants with POAG suffered from visual impairment in various degrees secondary to POAG. The percentage of blindness in either eye was 33.33%.· CONCLUSION: The prevalence of POAG is close to that from other Chinese populations, increasing with age. A majority of glaucoma was undiagnosed and untreated previously.
7.Experimental study of the eyelid reconstruction in situ with the acellular xenogeneic dermal matrix.
Jing LI ; Li LI ; Bai-Chao REN
Chinese Journal of Plastic Surgery 2007;23(2):154-157
OBJECTIVETo investigate the histocompatibility of acellular xenogeneic dermal matrix implanted in the rabbit eyelid reconstruction in situ and to compare the histological change of acellular xenogeneic dermal matrix and sclera replacing tarsus.
METHODSThirty-six New Zealand rabbits were divided into two groups randomly. Establishment of the rabbits unilateral eyelid defect model, the eyelid reconstruction in situ were performed with either acellular xenogeneic dermal matrix or allogeneic sclera at random. The rabbits were clinically examined for inflammation and implant exposure and sacrificed 1, 2, 4, 6, 8 and 12 weeks after implantation. The eyelid with implant (Xeno-ADM or allogeneic sclera) were dislodged and the specimens were assessed histopathologically and ultrastructurally with light microscopies respectively for evaluation of change of juncture between implant and autoallergic tarsal plates including inflammation, vascularization and confluence. The 4, 8 and 12 weeks specimens were assessed with transmission electron microscope micro structural changes of the above organizations.
RESULTSLight microscopy and electron microscopy showed no statistical difference between two groups. But histological examination showed that eyelid implanted with acellular xenogeneic dermal matrix had less immunological and inflammatory reaction than sclera-implanted group. Acellular xenogeneic dermal matrix could induce neovascular and collagenous fibers into implanted tissue.
CONCLUSIONAcellular xenogeneic dermal matrix is histocompatible to New Zealand rabbit, it can be used to support the eyelid as a substitution for tarsus.
Animals ; Biocompatible Materials ; Biological Dressings ; Blepharoplasty ; methods ; Dermis ; cytology ; transplantation ; Female ; Male ; Rabbits
8.Prevalence of trachoma trichiasis and corneal opacity in the Shaanxi Province of China
Chen-Jing, ZHOU ; Yu-Hong, CHENG ; Qiang, MA ; Jun, JIA ; Yuan, HE ; Li-Ling, ZHANG ; Bai-Chao, REN
International Eye Science 2016;16(8):1534-1536
Abstract?AIM: To assess the current situation of trachoma in Shaanxi Province and analyze its epidemiology and clinical features.?METHODS: The World Health Organization ( WHO ) simplified trachoma grading system was used for the recognition and registration of cases of trachoma. Trachoma rapid assessment ( TRA ) was conducted and 30.3687 million people from Shaanxi province were screened. Eyelids, eyelashes, conjunctiva and cornea were examined.The prevalence of trachoma trichiasis ( TT) in Shaanxi Province was estimated.?RESULTS: Totally 987 cases with TT were collected in Shaanxi province, in which 395 cases were male and 592 cases were female. The overall TT prevalence was 0.0325‰.The age of TT cases ranged from 25-86 years old, and concentrated in the 60-80 years old, only 58 cases were <50 years old.There were 12 cases of TT combined corneal opacity (CO) and the ratio was 1.2%. Sixty-four patients were cured by electrolysis trichiasis, the remaining 923 patients corrected by surgery interventions.?CONCLUSION: Based on the results of this study, trachoma blind is no longer estimated as a public health problem in Shaanxi province, as the detection rate of TT was less than 1‰ which is the goal of “elimination of trachoma” worldwide.
9.Properties of NiTi wires with direct electric resistance heat treatment method in three-point bending tests.
Hong-mei WANG ; Bang-kang WANG ; Chao-chao REN ; Yu-xing BAI
Chinese Journal of Stomatology 2011;46(3):168-171
OBJECTIVETo investigate the mechanical properties of Ni-Ti wires with direct electric resistance heat treatment (DERHT) method in three-point bending tests.
METHODSTwo superelastic Ni-Ti wires (wire A: Smart SE, wire B: SENTALLOY SE, 0.406 mm × 0.559 mm) and 2 heat-actived Ni-Ti wires (wire C: Smart SM, wire D: L&H TITAN, 0.406 mm × 0.559 mm) were selected. They were heat-treated using the DERHT method by a controlled electric current (6.36 A) applied for different period of time [0 (control), 1.0, 1.5, 2.0, 2.5 seconds). Then, a three-point bending test was performed under controlled temperature (37°C) to examine the relationships between the deflection and the load in the bending of wires.
RESULTSAfter DERHT treatment, the plateau in the force-deflection curve of superelastic Ni-Ti wires and heat-activated Ni-Ti wires were increased. When the wires were heated for 2.0 seconds and deflected to 1.5 mm, the loading force of A, B, C and D Ni-Ti wires increased from (3.85 ± 0.11), (3.62 ± 0.07), (3.28 ± 0.09), (2.91 ± 0.23) N to (4.33 ± 0.07), (4.07 ± 0.05), (4.52 ± 0.08), (3.27 ± 0.15) N respectively.
CONCLUSIONSDERHT method is very convenient for clinical use. It is possible to change the arch form and superelastic force of NiTi wires. The longer the heating time is, the more the superelastic characteristics of the wires are altered.
Dental Stress Analysis ; Elasticity ; Hot Temperature ; Materials Testing ; Nickel ; chemistry ; Orthodontic Wires ; Stress, Mechanical ; Titanium ; chemistry
10.Phase transformation analysis of varied nickel-titanium orthodontic wires.
Chao-chao REN ; Yu-xing BAI ; Hong-mei WANG ; Yu-feng ZHENG ; Song LI
Chinese Medical Journal 2008;121(20):2060-2064
BACKGROUNDThe shape memory effect of nickel-titanium (NiTi) archwires is largely determined by the phase transition temperature. It is associated with a reversible transformation from martensite to austenite. The aim of this study was to characterize austenite, martensite and R phase temperatures as well as transition temperature ranges of the commonly used clinical NiTi orthodontic arch wires selected from several manufacturers.
METHODSDifferential scanning calorimetry (DSC) method was used to study the phase transformation temperatures and the phase transition processes of 9 commonly used clinical NiTi alloys (types: 0.40 mm (0.016 inch), 0.40 mm x 0.56 mm (0.016 inch x 0.022 inch)).
RESULTSThe austenite finish temperatures (Af) of 0.40 mm Smart, Ormco and 3M NiTi wires were lower than the room temperature, and no phase transformation was detected during oral temperature. Therefore, we predicted that these types of NiTi did not possess shape memory property. For 0.40 mm and 0.40 mm x 0.56 mm Youyan I NiTi wires, no phase transformation was detected during the scanning temperature range, suggesting that these two types of wires did not possess shape memory either. The Af of 0.40 mm x 0.56 mm Smart, L&H, Youyan II Ni-Ti wires were close to the oral temperature and presented as martensitic-austenitic structures at room temperature, suggesting the NiTi wires listed above have good shape memory effect. Although the 0.40 mm x 0.56 mm Damon CuNiTi wire showed martensitic-austenitic structures at oral temperature, its Af was much higher than the oral temperature. It means that transformation from martensite to austenite for this type of NiTi only finishes when oral temperature is above normal.
CONCLUSIONThe phase transformation temperatures and transformation behavior varied among different commonly used NiTi orthodontic arch wires, leading to variability in shape memory effect.
Calorimetry, Differential Scanning ; Dental Alloys ; chemistry ; Nickel ; chemistry ; Orthodontic Wires ; Temperature ; Titanium ; chemistry