No abstract available.
Thyroid Diseases* ; Thyroid Gland*

No Abstract Available.
Thyroid Diseases* ; Thyroid Gland*

The 5 year-survival rates were examined to evaluate the prognositic significance of the expression of the p53 protein and the positivity of the PCNA in 108 cases of advanced gastric carcinoma. The p53 protein and PCNA were stained by immunohistochemistry in the tissue of the gastrectomized specimen. The results were as follows. 1) The overall 5 year-survival rate of advanced gastric carcinoma was 42.3 % and the significant prognostic factors were a pathologic stage and p53 protein(p<0.005). 2) The expanding or infiltrating type by Ming's classification and the intestinal or difftise type by Lauren's classification had similar prognosis. 514_ @@l %R-t 3) The 5 year-survival rate of the p53-positive group was 25.1% and that of p53-negative group was 56.1%(p<0.005). 4) The 5 year-survival rate of the PCNA low-grade tumors by PCNA stain(<50%)was 48.7% and that of the high-grade tumor(>=50%)was 29.9%(p>0.1). 5) There was a tendency to have a good prognosis in the p53-negative group and low grade tumors in the stage 11, III, and IV. There was a significant difference between p53 protein positive and negative groups in the stage III(p<0.005), but no significant differences were found in the other groups. The above results indicate that the p53 protein is an another useful tool for prediction of the prognosis in advanced gastric carcinoma.
Stomach Neoplasms

BACKGROUND: Disinfection is essential for the prevention of hospital infection. HICLO-S (Soosan environment Co., Yongin, Korea), one of the electrolyzed oxidized water was recently developed as a disinfectant. This is not costly and does not cause any clinical problems and environmental pollution. We evaluated the disinfective activity of HICLO-S against several clinical isolates of bacteria and yeasts. METHODS: 25 strains of bacteria and two strains of yeast were exposed to HICLO-S (30 & 50 ppm HICLO-S) disinfectant for the various periods (0.5, 1, 2, 4, 8, 10, 15, 20 minutes). After the exposure to HICLO-S disinfectant, 0.01 mL of mixture of microorganisms and HICLO-S was inoculated into brain-heart infusion broth or onto Sabouraud dextrose agar and incubated at 35degrees C for 48hours. RESULTS: All strains of bacteria and yeast were killed within 30 seconds after an exposure to 30 ppm of HICLO-S. All of three strains of spore forming Bacillus subtilis were killed within 4 minutes after an exposure to 30ppm of HICLO-S, but all of three strains were killed within 30 seconds in 50 ppm of HICLO-S. CONCLUSIONS: This study showed that HICLO-S disinfectant was effective for the disinfection of commonly isolated bacteria and yeast from hospital, but less effective against spore-forming bacteria. It may be recommended that HICLO-S should he used for the effective disinfection of skin, instruments and hospital floors.
Agar ; Bacillus subtilis ; Bacteria ; Cross Infection ; Disinfection ; Environmental Pollution ; Glucose ; Gyeonggi-do ; Skin ; Spores ; Water ; Yeasts

Copper fragment was introduced into the vitreous body of fourteen albino rabbits through the scleral incision at equatorial region. Both photopic and scotopic ERGs were recorded for 30 days thereafter stimulated by the electronic photoflash of 2 msec duration.The changes in scotopic b-potential were roughly classified into 3 types. The first type (5 eyes) showed acute, severe reduction, extinguishing from 6 to 24 days. The second type (3 eyes) was characterized by the absence of any remarakble changes during the whole observation period, the final b'potential being 82,4% of the original value. In the third type (6 eyes), the b-potential decreased gradually and 24.3% of the pre' operative value was attained after 30 days. The latent time and the implicit time of the b-potential increased proportionally to the reduction of the b-wave. The scotopic a-wave behaved parallel to the b-wave, and in later stage, negative (-) type of ERGs were frequently encountered. The photopic a- and b-waves changed in the similar way as the scotopic a- and b-waves, respectively. The slitlamp biomicroscopy and ophthalmoscopy revealed the fibrous tissue proliferation around the copper fragment in relatively early stage. When the proliferation progressed and extended into the vitreous body, ERG showed reduction in b-potential, and sometimes increase in b-potential was noted In cases in which connective tissue encapsulated the copper and did not extend into the vitreous body, ERG changes were much milder and slower. In histological sesctions performed 2 weeks and 3 weeks after the insertion of copper fragment, the degeneration of the retina began both in the visual cell layer and ganglion cell layer almost simultaneously. When the ERG was extinguished, the retinal tissue showed complete destruction.
Connective Tissue ; Copper* ; Ganglion Cysts ; Ophthalmoscopy ; Rabbits ; Retina ; Retinaldehyde ; Vitreous Body

No abstract available.

No abstract available.
Heart Valve Diseases* ; Heart Valves* ; Heart*

BACKGROUND: The risk of rubella infection is higher among hospital employees than others because of more exposure to rubella viruses. Because rubella infection during pregnancy can cause congenital rubella syndrome, special preventive measures should be taken for female employees in the hospital. METHODS: 309 employees in Soonchunhyang Kumi Hospital, aged from 18 to 45 years old, were included this study. Rubella IgG antibody was detected by the method of MEIA (microparticle enzyme immunoassay). And non-immunized employees were received by Wister RA 27/3 rubella vaccination and rechecked rubella antibody titers at 2 months later after vaccination. RESULTS: Among 309 subjects, 276(89.3%) were positive for rubella IgG antibody. The overall mean titer of rubella antibody was 72 IU/mL (SD: 67 IU/mL). The rubella antibody in titer decreased gradually with aging. The seroconversion rate after vaccination was 100%(28/28). CONCLUSIONS: The authors recommend that the employees susceptible to rubella or all employees in the hospital should be vaccinated for preventing rubella.
Aging ; Cross Infection* ; Female ; Gyeongsangbuk-do ; Humans ; Immunoglobulin G ; Middle Aged ; Pregnancy ; Rubella Syndrome, Congenital ; Rubella Vaccine ; Rubella virus* ; Rubella* ; Vaccination*

No abstract available.
Pregnancy* ; Substance-Related Disorders*

No abstract available.
Thyroid Gland* ; Thyroid Neoplasms*