No abstract available.
Arthroplasty* ; Knee*

No abstract available.
eIF-2 Kinase* ; HIV-1* ; Phosphorylation

No abstract available.
Hemosiderosis* ; Humans ; Kidney Failure, Chronic* ; Seizures*

No abstract available.
Orthognathic Surgery

Since the segmental fractures of the femur are resulted by violent force, they are frequently associated with severe soft tissue damage and multiple skelectal injuries and they necessitated careful emergency care. Occasionally, they combined with severe communition, so their ultimate fixation of the fractures are very difficult. Authors analysed sixteen fractures of the segmental fracture of the femur which were treated by intramedullary nailing with or without interlocking at the Kyung Hee University, medical college, from the December, 1975 to May, 1985. In eight of sixteen cases the nailing was done by closed technique, one case was semiclosed. In the seven fractures the traditional retrograde nailing technique with open reduction of fracture was used. The pin & plaster, cast brace, side bone plate, wiring or interlocking screws were used as additional stabilization to intramedullary nailing. The diameter of the nails were 9–12 mm in 5 cases, 13–15 mm in 11 cases. There were no need the cancellous bone graft to promote the bony union. The results were as follows; 1. The closed intramedullary nailing with interlocking screw offers an ideal anatomical, functional and physiological treatment for the segmental fracture of the femur. 2. When the segmental fracture of the femur involves the neck or supra- or intercondylar fractures, the intramedullary nailing can be used with Knowles pin or tibial bolt fixation. 3. In the cases of infected nonunion, we obtained solid bony union by means of extensive and meticulous debridement and rigid intramedullary nailing using additional devices without cancellous bone graft.
Bone Plates ; Braces ; Debridement ; Emergency Medical Services ; Femur ; Fracture Fixation, Intramedullary ; Neck ; Transplants

No abstract available.
Thyroid Gland*

BACKGROUND AND OBJECTIVE: Many chemical mediators such as histamine, prostaglandins, leukotrienes, bradykinin, angiotensisn II (A II), and even angiotensin converting enzyme (ACE) affect the pathophysiology of asthma. ACE exists in the epithelium, endothelium, neuroepithelium, plasma, and especially in high concentrations in human lung tissue. ACE converts A I to A II, which is highly vasoconstrictive, bronchoconstrictive, inflammatory substance, and can also inactivate bradykinin. ACE polymorphism determines the level of ACE such as DD, higher concentration of ACE, but II, lowest concentration of that, so in DD type, the level of A II increase, but that of bradykinin decrease. From that point we can speculate polymorphism of ACE gene anyhow affects asthma, so we carried out this study for evaluating relationships between the ACE genotype distribution and genesis and severity of asthma in Korean adult asthmatics. MATERIALS AND METHODS: The study population consisted of 150 asthmatics, 57 patients of non asthmatic lung diseases including lung cancer (n=10), pulmonary tuberculosis (n=27), empyema (n=3), pneumonia (n=11), bronchiectasis (n=5) and lung abscess (n=1) and 100 normal healthy subjects without hypertension, cardiovascular disease, diabetes mellitus and nephropathy which may bias the result. Bronchial asthmatics were classified into 3 groups according to the criteria of the NAPE. PCR (polymerase chain reaction) for ACE genotypes was performed. PCR products were electrophoresed in 1% agarose gels, and then DNA pattern was directly visualized under ethidium bromide staining. RESULTS: The frequency for II, ID, and DD genotypes were 46 (46%), 38 (38%), 16 (16%) in control group, 59 (39.6%), 74 (49.5%), 17 (10.9%) in asthma group and 28 (49.1%), 24 (42.1%), 5 (8.8%) in non-bronchial lung disease group, respectively. There was no signi- ficant difference in frequency of ACE genotype distribution among the 3 groups (p > 0.05). The frequency for II, ID, and DD genotypes in the 3 groups of asthmatics were 17 (34%), 27 (54%), 6 (12%) in mild subset, 13 (26%), 30 (60%), 7 (14%) in moderate subset, and 11 (22%), 33 (66%), 6 (12%) in severe subset. Even though there was also no significant difference among the 3 severity subsets in the asthma group, the frequency of non-DD subsets such as II and ID was higher in moderate and severe asthmatics. CONCLUSION: The results suggest that ACE gene polymorphism dose not affect the genesis but can progress asthma in Korean adult asthmatics. However, further mass studies on asthmatics will be needed to clarify the effect of ACE polymorphism on the severity of Korean adult asthmatics.
Adult* ; Angiotensin I* ; Angiotensins* ; Asthma* ; Bias (Epidemiology) ; Bradykinin ; Bronchiectasis ; Cardiovascular Diseases ; Diabetes Mellitus ; DNA ; Empyema ; Endothelium ; Epithelium ; Ethidium ; Gels ; Genotype ; Histamine ; Humans ; Hypertension ; Leukotrienes ; Lung ; Lung Abscess ; Lung Diseases ; Lung Neoplasms ; Peptidyl-Dipeptidase A* ; Plasma ; Pneumonia ; Polymerase Chain Reaction ; Prostaglandins ; Sepharose ; Tuberculosis, Pulmonary

Extrapelvic endometriosis is a rare disease. The majority of extrapelvic endometriosis cases involve scar tissue following obstetric and gynecologic procedures. We have treated two cases of extrapelvic incisional endometriosis. A 39 year old female patient with cyclic vaginal spotting after laparoscopic assisted vaginal hysterectomy due to uterine myoma and a 35 year old female patient with a painful palpable abdominal mass after cesarean section. Both underwent complete excision and were proven to have endometriosis by pathology. Here we report on both cases and review the medical literatures.
Adult ; Cesarean Section* ; Cicatrix ; Endometriosis* ; Female ; Humans ; Hysterectomy, Vaginal* ; Leiomyoma ; Metrorrhagia ; Pathology ; Pregnancy ; Rare Diseases

No abstract available.
Hearing* ; Humans ; Tinnitus*

No abstract available.
Dyskeratosis Congenita*