ABSTRACT
Acromegaly is a devastating chronic slowly progressive disease. Its early diagnosis is a challenging
issue that necessitates clinical suspicion of signs and symptoms as a first step. This report introduces
an unusual early sign in the oral cavity that lead to the early diagnosis of an acromegaly case. A case
of a healthy 40-year-old male patient presented with progressively growing multiple hard swellings in
the upper and lower jaws. Clinical examination revealed bony hard multiple small spiky exostosis-like
swellings, located at the maxillary and mandibular alveolar bones. An array of investigations revealed a
2-mm diameter pituitary tumour in MRI of sella. To the best of the author’s knowledge, this is the first
report of spiky exostosis-like growths in the alveolar bone as an early sign of acromegaly. In this case,
thorough examination of oral signs and symptoms was the first step for early diagnosis and hence, better
prognosis for acromegaly.
Acromegaly--diagnosis