1. Isolation and structural elucidation of antifungal compounds from Curcuma amada
Jesmin AKTER ; Md HOSSAIN ; De-Xing HOU ; Kensaku TAKARA ; Md. ISLAM ; Md HOSSAIN ; Ayako SANO
Asian Pacific Journal of Tropical Medicine 2019;12(3):123-129
Objective: To isolate and identify the antifungal compounds from Curcuma amada. Methods: The antifungal activity was measured by the diameter of colonies grown on Petri dish, microscopic observation, and CLSI microdilution methods. The antifungal compounds were isolated through bioactivity guided purification by using silica gel and high-performance liquid chromatography. Structural identification of the antifungal compounds was conducted using
2.Initiatives for the Establishment of the Network of Regional Medical Institutions regarding Palliative Care at the National Cancer Center in Japan
Ayako SATO ; Madoka YAMAZAKI ; Tomomi SANO ; Emi TAKEUCHI ; Yutaka MATSUOKA ; Saho WADA
Palliative Care Research 2025;20(1):81-87
Background: The National Cancer Center Institute for Cancer Control has trained regional palliative care coordinators to disseminate personnel promoting collaboration between cancer hospitals and regional institutions. We examined the effectiveness of the training. Methods: A questionnaire survey was conducted in February 2022 among facilities participating in the training sessions from 2016 to 2021. Results: One-hundred sixteen facilities responded. The results were classified as ‘positive change (78%)’ and ‘negative change (0%)’. Regarding ‘factors inhibiting the smooth transition of terminal cancer patients from hospital to home,’ ‘patients’ social background (e.g., living alone, old age, etc.) interferes with the transition to home care (88%)’ and ‘patients’ anxiety about home care (83%)’ were the most common factors. Conclusion: Nearly 80% of participants reported positive changes, indicating that the training has had a certain effect. With regard to inhibiting factors, we plan to consider how training should be conducted so that it can address the individual issues in each region.