1.Research advances on the clinical characteristics and diagnosis and treatment of autoimmune disease-related ulcers.
Ling ZHAO ; Kai Sheng SU ; Zhuang YE ; Zhen Yu JIANG ; Lu CHEN ; Yu LONG
Chinese Journal of Burns 2022;38(6):558-562
Studies have shown that autoimmune disease (AID)-related ulcers are disease complications that lead to serious poor prognosis such as infection and disability. It is difficult to make a clear diagnosis and there are contradictions between the applications of immunosuppressive therapy and anti-infectious therapy. Improper diagnosis and immunosuppressive therapy can easily delay the timing of anti-infectious therapy and surgery for patients, which bring adverse effects on the prognosis of patients. This paper reviews the concept, clinical characteristics and treatment suggestions of each subtype of AID-related ulcers, in order to provide more ideas for AID-related ulcers' clinical diagnosis and treatment.
Autoimmune Diseases/therapy*
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Humans
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Ulcer/complications*
3.Advances on the research and treatment of autoimmune disease-related chronic wounds.
Lu ZHANG ; Xing Tong WANG ; Wan Li CHU
Chinese Journal of Burns 2022;38(6):563-568
Autoimmune disease is a disease caused by the body's immune system being misdirected to attack the host itself. Patients with this type of diseases are in poor general condition, and are affected by vascular and skin tissue lesions, and therapeutic drugs. Once the skin is broken, chronic wounds that do not heal could easily develop. This type of wounds is difficult to treat and requires joint diagnosis and treatment of multidisciplinary physicians. Therefore, this article reviews the advances on research and treatment of autoimmune disease-related chronic wounds in order to provide reference for their clinical treatment.
Autoimmune Diseases/therapy*
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Humans
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Skin
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Skin Diseases/therapy*
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Wound Healing
4.Progress on the diagnosis and therapy about atopic diseases and primary immunodeficiency diseases.
Zhou Xian PAN ; Ying Yang XU ; Sai Nan BIAN ; Ji LI ; Yu Lin JIANG ; Ji LI ; Kai GUAN
Chinese Journal of Preventive Medicine 2022;56(9):1218-1225
Primary immunodeficiency diseases (PID) is a congenital disease caused by single gene germline mutation related to the immune system. PID patients have immune dysregulation, and are susceptible to infectious diseases, autoimmune diseases, autoimmune diseases, allergic diseases, and malignant tumors. The first symptom of some PID patients is atopic disease, therefore they go to the department of allergy, department of pediatrics and other relevant departments. How to identify and diagnose PID in allergic patients, to reduce diagnosis delay and prevent disease aggravation are the abilities that allergists, pediatricians, and doctors in other relevant departments need to master. This article summarizes the warning signs of PID in allergic patients and the mechanism of allergy combined with PID, and then summarizes the common types of PID in allergic patients, the evaluation, treatment and prevention in patients with PID and allergy.
Autoimmune Diseases
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Child
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Humans
;
Hypersensitivity/therapy*
;
Immunologic Deficiency Syndromes/therapy*
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Primary Immunodeficiency Diseases/therapy*
5.Progress in autoimmune liver diseases.
Hong YOU ; Ya-meng SUN ; Ji-dong JIA
Chinese Journal of Hepatology 2013;21(2):87-89
Autoimmune Diseases
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diagnosis
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genetics
;
therapy
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Humans
;
Liver Diseases
;
diagnosis
;
genetics
;
therapy
6.Guidelines on the management of cholestasis liver diseases (2021).
Chinese Journal of Hepatology 2022;30(3):253-263
In 2015, the Chinese Society of Hepatology and Chinese Society of Gastroenterology issued the consensus on the diagnosis and management of cholestatic liver diseases. In the past years, more data have emerged from clinical practice. Herein, the Autoimmune Liver Disease Group of the Chinese Society of Hepatology organized an expert group to review the evidence and updated the recommendations to formulate the guidelines. There are 22 recommendations on clinical practice of cholestatic liver diseases. The guidelines aim to provide a working reference for the management of cholestatic liver diseases.
Autoimmune Diseases/diagnosis*
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Cholestasis/therapy*
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Consensus
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Gastroenterology
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Humans
;
Liver Diseases/therapy*
7.IgG4-related diseases with autoimmune hemolytic anemia: A case report.
Manxuan PEND ; Lizhen YANG ; Shangjie WU
Journal of Central South University(Medical Sciences) 2020;45(6):739-744
IgG4-related disease (IgG4-RD) is a rare autoimmune fibrosis disease characterized by elevated serum IgG4 and tissues as well as organs infiltrated with IgG4-positive cells, resulting in swelling and damage.It is currently treated as first-line treatment with glucocorticoids. Autoimmune hemolytic anemia (AIHA) is also a relatively rare disease that caused by autoreactive erythrocyte antibodies. Although both are autoimmune-related diseases, they rarely overlap. The relationship between them is not clear. A case of IgG4-RD combined with AIHA is reported. The patient has shortness of breath, cough, and sputum after physical activity. Physical examination showed appearance of anemia, yellow staining of skin and sclera, palpable neck and multiple swollen lymph nodes. Laboratory examination, bone marrow biopsy, and lymph node biopsy confirmed the diagnosis. Therefore, clinicians should develop ideas and raise awareness of such diseases.
Anemia, Hemolytic, Autoimmune
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diagnosis
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drug therapy
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Autoimmune Diseases
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complications
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Biopsy
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Humans
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Immunoglobulin G
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Immunoglobulin G4-Related Disease
;
complications
;
diagnosis
8.A review of the clinical progress on helminths and their derivative products in autoimmune disease.
Xinyue WU ; Hongyu GAO ; Shuyao DUAN ; Wenbo DING ; Xiaodi YANG
Chinese Journal of Cellular and Molecular Immunology 2023;39(12):1132-1140
Traditional medications used for treating autoimmune diseases often come with a wide range of adverse effects. Current treatments focus mainly on symptom management, resulting in significant health issues and financial burdens for patients. Recently, clinical research has demonstrated the potential of helminths and their derivatives as effective therapies for autoimmune disorders. Helminths, being a near-natural immunomodulator, exhibit milder effects than broad-spectrum immunosuppressants and corticosteroids, thereby presenting a promising alternative for the treatment of autoimmune diseases. However, different helminths' therapeutic efficacy and mechanisms and their derivatives in treating autoimmune diseases may vary. Therefore, we aim to review recent clinical advancements in the use of helminths and their derivatives for treating inflammatory bowel disease, multiple sclerosis, and autism spectrum disorder, with a view to offering novel clinical treatment approaches.
Animals
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Humans
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Autism Spectrum Disorder
;
Autoimmune Diseases/drug therapy*
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Helminths
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Inflammatory Bowel Diseases
9.Steroid Treatment of Autoimmune Pancreatitis.
The Korean Journal of Gastroenterology 2006;47(6):467-469
No abstract availble.
Autoimmune Diseases/*drug therapy
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Glucocorticoids/*therapeutic use
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Humans
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Pancreatitis, Chronic/*drug therapy/immunology
10.Autoimmune cholangitis.
Chinese Journal of Hepatology 2004;12(11):703-704
Autoimmune Diseases
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diagnosis
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etiology
;
therapy
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Cholangitis
;
diagnosis
;
etiology
;
therapy
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Diagnosis, Differential
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Humans