Myiasis is an infestation of maggot, which is frequently associated with poor personal hygiene and environmental sanitation. A 78-year-old female breast cancer patient visited clinic complaining of irritation, itching, and pain within the ulcerous cancer lesion for 3 weeks. Many maggots were found in the lesion. A total of 30 maggots were removed and identified to be 3rd stage of larvae of metallic fly. This is the first case of wound myiasis in advanced breast carcinoma as a complication of untreated or drug-induced ulcer.

Background: Many studies have shown that exercise can effectively reduce the non-high density lipoprotein cholesterol (non-HDL-C) level, one of the major risk factors for cardiovascular diseases, in different sex and age groups. However, there are very few studies conducted in older women, who are in a group having a higher mortality rate due to cardiovascular diseases. Moreover, there has been no recent meta-analysis focusing on the effect of exercise on non-HDL-C level in older women. The purpose of this study was to investigate the effect of exercise on non-HDL-C level in older women (≥50 years old) by means of systematic review and meta-analysis of previous randomised controlled trials. Methods: Searches were conducted from 9 electronic databases by applying specific eligibility criteria of the review. Data regarding changes in non-HDL-C, high density lipoprotein cholesterol (HDL-C) and total cholesterol levels, were extracted as primary outcomes. Random-effect meta-analysis was used to calculate pooled effect sizes of primary and secondary outcomes. Results: Ten studies that met the inclusion criteria were selected for meta-analysis. Random-effect meta-analysis showed statistically significant reduction in non-HDL-C level (= -9.69 mg/dL; 95%CI= -17.09 to -2.29 mg/dL; p<0.05) and increase in HDL-C level (= 3.0mg/dL; 95%CI= 0.61 to 5.4; p<0.05), but no significant change in total cholesterol level (= -5.99 mg/dL; 95%CI= -12.64 to 0.66; p>0.05) in the exercise group compared to the control group. Subgroup analysis of data from different continents showed significant subgroup differences in the non-HDL-C level after exercise (Q= 12.39; p<0.005; I2= 83.9%). Conclusion Exercise decreases non-HDL-C level and increases HDL-C level in older women and might be efficacious in preventing dyslipidemia and associated diseases in older women.
Exercise ; Meta-Analysis [Publication Type]

BACKGROUND: More than 140 million people drink arsenic-contaminated groundwater. It is unknown how much arsenic exposure is necessary to cause neurological impairment. Here, we evaluate the relationship between neurological impairments and the arsenic concentration in drinking water (ACDW). PARTICIPANTS AND METHODS: A cross-sectional study design was employed. We performed medical examinations of 1867 residents in seven villages in the Thabaung township in Myanmar. Medical examinations consisted of interviews regarding subjective neurological symptoms and objective neurological examinations of sensory disturbances. For subjective neurological symptoms, we ascertained the presence or absence of defects in smell, vision, taste, and hearing; the feeling of weakness; and chronic numbness or pain. For objective sensory disturbances, we examined defects in pain sensation, vibration sensation, and two-point discrimination. We analyzed the relationship between the subjective symptoms, objective sensory disturbances, and ACDW. RESULTS: Residents with ACDW ≥ 10 parts per billion (ppb) had experienced a "feeling of weakness" and "chronic numbness or pain" significantly more often than those with ACDW < 10 ppb. Residents with ACDW ≥ 50 ppb had three types of sensory disturbances significantly more often than those with ACDW < 50 ppb. In children, there was no significant association between symptoms or signs and ACDW. CONCLUSION Subjective symptoms, probably due to peripheral neuropathy, occurred at very low ACDW (around 10 ppb). Objective peripheral nerve disturbances of both small and large fibers occurred at low ACDW (> 50 ppb). These data suggest a threshold for the occurrence of peripheral neuropathy due to arsenic exposure, and indicate that the arsenic concentration in drinking water should be less than 10 ppb to ensure human health.
Adolescent ; Adult ; Arsenic ; analysis ; toxicity ; Cross-Sectional Studies ; Dietary Exposure ; adverse effects ; Dose-Response Relationship, Drug ; Drinking Water ; adverse effects ; chemistry ; Female ; Groundwater ; chemistry ; Humans ; Male ; Middle Aged ; Myanmar ; epidemiology ; Peripheral Nervous System Diseases ; chemically induced ; epidemiology ; physiopathology ; Sensation Disorders ; chemically induced ; epidemiology ; physiopathology ; Water Pollutants, Chemical ; analysis ; toxicity ; Young Adult