2.Polypharmacy in a nine year old boy with Attention Deficit Hyperactivity Disorder and Tourette Syndrome: what worsened the ties?
Wan Salwina Wan Ismail ; Aili Hanim Hashim ; Manveen Kaur ; Shell Pin Choo ; Fairuz Nazri Abdul Rahman
Malaysian Journal of Medicine and Health Sciences 2014;10(2):79-81
Introduction: Attention Deficit Hyperactivity Disorder(ADHD) and Tourrete Syndrome(TS) commonly
co-occur, imposing a special challenge in the management. Case report: This is a case of a nine year old
boy with ADHD and TS, who had been on methylphenidate, risperidone, fluvoxamine and atomoxetine,
alone and in combination. Tics worsened with methylphenidate but improved after its withdrawal, and
the addition of risperidone and fluvoxamine. Later, atomoxetine was added which worsened the tics,
even when it was removed. Significant improvement in the tics were only obvious when fluvoxamine
was taken off. Discussion: The possible roles of dopamine and serotonin neurotransmission, and
metabolism of cytochrome P450 D26 in the pathophysiology were discussed. Conclusion: The use of
multiple medications need cautious consideration and monitoring in a child patient to avoid unwanted
complications and risks.
Attention Deficit Disorder with Hyperactivity
3.Neurological soft signs in patients with attention deficit hyperactivity disorder aged 6 to 18 years old at a University Hospital: A cross-sectional study
Rowena ARCA-CABRADILLA ; Rosalina Q DE SAGUN ; Maria Antonia Aurora M VALENCIA ; Michelle SY
Journal of Medicine University of Santo Tomas 2020;4(1):407-422
Purpose:
Attention defi cit hyperactivity disorder
(ADHD) is a common neurodevelopmental disorder in children persisting into adulthood. Evidence
suggests that the condition is etiologically related to
delayed brain maturation. The detection of the presence of neurological soft signs can be a means to
assess neuromaturation. The objective of this study
was to assess the prevalence of neurological soft
signs in ADHD patients and determine any correlation between the presence of neurological soft signs
with age, gender, severity and type of ADHD which
could give further insights into this disorder.
Methods:
A cross-sectional study was conducted at the Child Neurology and Developmental
Pediatrics outpatient clinic which included patients 6-18 years old diagnosed with ADHD as well as
healthy controls. Patients with other neurodevelopmental conditions (intellectual disability, metabolic
disorder, cerebral palsy, abnormal MRI fi ndings), or
any condition that may lead to failure to complete
the given tasks such as physical handicaps were excluded. Neurological soft signs were measured by
utilizing the Physical and Neurological Evaluation
for Soft Signs (PANESS) scale.
Key Findings:
A total of 48 patients between 6 and
18 years of age (24 ADHD patients and 24 healthy
controls) were examined. Neurological soft signs
were signifi cantly higher in patients with ADHD and
were present regardless of gender, type and severity
of ADHD. ADHD patients performed worse on the
given tasks as evidenced by higher PANESS scores.
There was a weak negative correlation between neurological soft signs and age indicating that soft sign
scores decrease with increasing age. There was no
statistically signifi cant difference in neurological soft
sign scores between those with medication versus
without treatment, except for dysrhythmia which was
signifi cantly higher in the drug-naive group.
Significance
Neurological soft signs are common
in patients with ADHD and add scientifi c evidence
to the predictive value of neurological soft signs as
indicators of the severity of functional impairment in
ADHD. The prevalence of neurological soft signs is
much higher in children with ADHD than in controls
which may have the potential to improve sensitivity
in the diagnosis of ADHD.
Attention Deficit Disorder with Hyperactivity
4.Orthodontics treatment strategy and management in a child with attention deficit hyperactivity disorder
Ricky Kurniawan ; Sindy Cornelia Nelwan ; Udijanto Tedjosasongko ; Tania Saskianti
Acta Medica Philippina 2019;53(5):469-473
This is a case of an 8-year-old male patient diagnosed with class 1 angle malocclusion, 9 mm overjet and 4.5 mm overbite, with thumb-sucking habit. The patient also has attention deficit hyperactivity disorder (ADHD). The goal of this study is to identify and determine appropriate orthodontics treatment management for patients with ADHD. Management behavior using behavioral shaping and tell-show-do technique during orthodontic treatment in patients with special needs contributes to how well the patient will cooperate with the dentists during treatment.
Attention Deficit Disorder with Hyperactivity
5.Food allergy-induced epilepsy with hyperkinetic syndrome: a case report.
Soon Young KIM ; Baek Hee LEE ; Se Hee HANG ; Yong Seung HWANG
Journal of the Korean Child Neurology Society 1993;1(1):193-199
No abstract available.
Attention Deficit Disorder with Hyperactivity*
;
Epilepsy*
6.Association between allergic diseases and Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in children aged 6-12 years using the Filipino version of the Vanderbilt ADHD Parent Rating Scale.
Glaiza M. MADULARA ; Agnes G. ANDAYA
Journal of Medicine University of Santo Tomas 2021;5(1):628-641
BACKGROUND: Over the last decades, the hypothesis that an allergic response could lead to the development of attention-deficit/hyperactivity disorder (ADHD) was raised and clinical studies investigated the co-existence of both. These studies had shown that allergic diseases and neurobehavioral disorders were concurrent and could be associated with genetic factors, neuroimmunity and microbial dysbiosis. To date, this was the first study in the Philippines to evaluate the prevalence and association of allergic diseases, its severity and ADHD symptoms.
OBJECTIVE: The objective of this study was to determine the association of allergic diseases and ADHD symptoms among children aged 6-12 years based on parental report using the Filipino version of the Vanderbilt ADHD Parent Rating Scale.
METHODS: School-aged children between 6 and 12 years with physician diagnosed allergies (bronchial asthma, allergic rhinitis, atopic dermatitis, allergic conjunctivitis, drug allergy, food allergy and/or acute or chronic urticaria) were randomly selected. Skin prick test (SPT) to aeroallergens was done. The parents completed the Filipino version of the Vanderbilt ADHD Diagnostic Parent Rating Scale (VADPRS), a screening tool for ADHD.
RESULTS: Among the 415 patients, 135 (32.5%) of them screened positive for ADHD symptoms. Upon assessment of the Vanderbilt parent rating subscale responses, 13.49% of the children were categorized as predominantly inattentive subtype, 6.02% as predominantly hyperactive/impulsive subtype and 13.01% as combined inattention/hyperactivity. Three hundred and seventy six (91%) children were diagnosed with asthma. Among these asthmatics, 119 (32%) had ADHD symptoms with the following subtypes - predominantly inattentive subtype (13.56%), predominantly hyperactive/impulsive subtype (5.05%) and combined inattention/hyperactivity (13.03%). Combined inattention/hyperactivity subtype had a significant proportion of severe asthmatics, as compared to mild or moderate asthma (p value = 0.026). Furthermore, 389 (94%) children were diagnosed with allergic rhinitis. Among these patients, 130 (33%) had ADHD symptoms with the following subtypes - predominantly inattentive subtype (13.62%), predominantly hyperactive/impulsive subtype (6.43%) and combined inattention/hyperactivity (13.37%). However, evidence was not sufficient to demonstrate an association between ADHD subtypes and allergic rhinitis severity. Lastly, 206 (50%) children were diagnosed with atopic dermatitis. Among these patients, 71 (34%) had ADHD symptoms with the following subtypes - predominantly inattentive subtype (14.56%), predominantly hyperactive/impulsive subtype (4.85%) and combined inattention/hyperactivity (15.05%). However, there was insufficient evidence to demonstrate a link between ADHD subtypes and atopic dermatitis severity.
CONCLUSION: Children with allergies, especially those with severe asthma, are more likely to have ADHD symptoms.
Attention Deficit Disorder with Hyperactivity ; Asthma
7.Panax Ginseng Extract in a Boy with Attention Deficit Hyperactivity Disorder.
Keun Jeong YUK ; Suk Hwa LEE ; Jin A DOH ; Myung Ho LIM ; Hyun Woo KIM
Korean Journal of Psychopharmacology 2010;21(1):35-39
New treatment strategies to attention deficit hyperactivity disorder (ADHD) have been introduced recently. We report and review the effect of Panax ginseng extract administration in a 7 year-old boy with drug naive ADHD. We administered Panax ginseng extract 1,800 mg/day to him for 8 weeks. There were improvement of scores in Attention Diagnostic System, Clinical Global Improvement, Conner's ADHD Rating scale and Dupaul ADHD Rating scale.
Attention Deficit Disorder with Hyperactivity
;
Panax
;
Polyenes