1.Visceral Obesity as a Risk Factor for Left-Sided Diverticulitis in Japan: A Multicenter Retrospective Study.
Eiji YAMADA ; Hidenori OHKUBO ; Takuma HIGURASHI ; Eiji SAKAI ; Hiroki ENDO ; Hirokazu TAKAHASHI ; Eri UCHIDA ; Emi TANIDA ; Nobuyoshi IZUMI ; Akira KANESAKI ; Yasuo HATA ; Tetsuya MATSUURA ; Nobutaka FUJISAWA ; Kazuto KOMATSU ; Shin MAEDA ; Atsushi NAKAJIMA
Gut and Liver 2013;7(5):532-538
BACKGROUND/AIMS: Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to obesity and conducted a study of the features and risk factors for this disorder in Japan. METHODS: Right-sided diverticulitis and left-sided diverticulitis patients (total of 215) were compared with respect to background, particularly obesity-related factors to identify risk factors for diverticulitis. RESULTS: There were 166 (77.2%) right-sided diverticulitis patients and 49 (22.8%) left-sided diverticulitis patients. The proportions of obese patients (body mass index > or =25 kg/m2, p=0.0349), viscerally obese patients (visceral fat area > or =100 cm2, p=0.0019), patients of mean age (p=0.0003), and elderly patients (age > or =65 years, p=0.0177) were significantly higher in the left-sided-diverticulitis group than in the right-sided-diverticulitis group. The proportion of viscerally obese patients was significantly higher in the left-sided-diverticulitis group than in the left-sided-diverticulosis group (p=0.0390). CONCLUSIONS: This study showed that obesity, particularly visceral obesity, was a risk factor for left-sided diverticulitis in Japan.
Aged
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Diverticulitis
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Humans
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Japan
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Obesity
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Obesity, Abdominal
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Retrospective Studies
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Risk Factors
2.Influence of Diabetes Mellitus on Surgical Outcomes in Patients with Cervical Myelopathy: A Prospective, Multicenter Study
Shinji TANISHIMA ; Tokumitsu MIHARA ; Atsushi TANIDA ; Chikako TAKEDA ; Masaaki MURATA ; Toshiaki TAKAHASHI ; Koji YAMANE ; Tsugutake MORISHITA ; Yasuo MORIO ; Hiroyuki ISHII ; Satoru FUKATA ; Yoshiro NANJO ; Yuki HAMAMOTO ; Toshiyuki DOKAI ; Hideki NAGASHIMA
Asian Spine Journal 2019;13(3):468-477
STUDY DESIGN: Multicenter, prospective study. PURPOSE: To investigate the effects of diabetes mellitus (DM) on surgical outcomes in patients with cervical myelopathy. OVERVIEW OF LITERATURE: To date, few studies have investigated the influence of postoperative blood glucose or glycated hemoglobin (HbA1c) levels on surgical outcomes. METHODS: The participants were patients who underwent surgery for the treatment of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament. The 61 cases were evaluated preoperatively and 1 year postoperatively using the Japanese Orthopaedic Association (JOA) scores and the JOA Cervical Myelopathy Evaluation Questionnaire (JOACMEQ). The study variables included fasting blood glucose and HbA1c levels measured preoperatively and at 1 week, 4 weeks, and 1 year postoperatively; the F-wave conduction velocity, latency, rate of occurrence, and M-wave latency in the ulnar and tibial nerves were measured preoperatively and at 1 year postoperatively. The patients were divided into a group without diabetes (N group, 42 patients) and a group with diabetes (DM group, 19 patients). We then assessed the associations between the surgical outcomes and each of the study variables. RESULTS: JOA scores significantly improved in both groups; however, no significant between-group differences were found. There was no significant improvement in the JOACMEQ scores, which assessed cervical function, upper and lower limb function, and bladder function in both groups. We then subdivided the DM group into those with a good control of HbA1c after 1 year (DMG group, 12 patients) and those with HbA1c deterioration after 1 year (DMB group, seven patients), prior to comparing the surgical outcomes. The JOACMEQ scores for upper and lower limb function significantly improved in the DMG group (p<0.01). Compared with the DMB group, there were no significant increases in upper or lower limb function scores in the DMG group. CONCLUSIONS: Poor glycemic control might prevent postoperative functional recovery of the spinal cord.
Asian Continental Ancestry Group
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Blood Glucose
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Diabetes Mellitus
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Electromyography
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Fasting
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Hemoglobin A, Glycosylated
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Humans
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Longitudinal Ligaments
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Lower Extremity
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Neck
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Prospective Studies
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Spinal Cord
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Spinal Cord Compression
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Spinal Cord Diseases
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Tibial Nerve
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Treatment Outcome
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Urinary Bladder