Adult ; Atrioventricular Block ; complications ; Cardiomyopathies ; complications ; diagnosis ; Humans ; Male ; Sarcoidosis ; complications ; diagnosis

Aged ; Atrioventricular Block ; diagnosis ; etiology ; physiopathology ; Diagnosis, Differential ; Electrocardiography ; Humans ; Male ; Osteitis Deformans ; complications ; pathology

Adult ; Anti-Inflammatory Agents ; therapeutic use ; Atrioventricular Block ; diagnosis ; etiology ; pathology ; Cranial Nerve Diseases ; diagnosis ; etiology ; pathology ; Humans ; Male ; Prednisolone ; therapeutic use ; Sarcoidosis ; complications ; diagnosis ; pathology

Congenital myotonic dystrophy (CMD) is an inherited neuromuscular disorder with cardiac rhythm abnormalities that may occur as a child grows. No report has described complete atrioventricular (AV) block detected in a neonate with CMD. We report a floppy infant of 31(+4) weeks gestation with complete AV block at birth, who was diagnosed with CMD by Southern analysis. She recovered from complete AV block 32 hr after temporary transcutaneous pacing was applied. To the best our knowledge, this is the first recorded case of a complete AV block accompanied by CMD during the neonatal period. When a newborn has a complete AV block, the physician should consider the possibility of the CMD and conduct a careful physical examination.
3' Untranslated Regions ; Atrioventricular Block/complications/*diagnosis ; Blood Gas Monitoring, Transcutaneous ; Chromosomes, Human, Pair 9 ; Electrocardiography ; Female ; Humans ; Infant, Newborn ; Myotonic Dystrophy/complications/*diagnosis/genetics ; Myotonin-Protein Kinase/genetics ; Trinucleotide Repeats

Anti-Ro autoantibody is associated with Sjogren's syndrome (SS), systemic lupus erythematosus (SLE), and neonatal lupus syndrome (i.e., congenital complete heart block in newborns). Generally, the adult atrioventricular (AV) node is believed to be relatively resistant to the scarring effects of anti-Ro/anti-La autoantibodies. However, there have been some reports of adult complete AV block in SS and SLE patients. Here, we report a case of complete heart block in primary SS with anti-Ro autoantibodies, with no other risk factor for the development of heart block, and review their etiological association.
Antibodies, Antinuclear/*blood ; Atrioventricular Block/diagnosis/*immunology/therapy ; Cardiac Pacing, Artificial ; Electrocardiography ; Electrocardiography, Ambulatory ; Exercise Test ; Female ; Humans ; Middle Aged ; Predictive Value of Tests ; Risk Factors ; Sjogren's Syndrome/complications/*immunology ; Treatment Outcome

This study aimed to assess the influence of lobectomy and pneumonectomy on cardiac rhythm and on the dimensions and function of the right-side of the heart. Twelve dogs undergoing lobectomy and eight dogs undergoing pneumonectomy were evaluated preoperatively and one month postoperatively with electrocardiography and Doppler echocardiography at rest. Pulmonary artery systolic pressure (PASP) was estimated by the tricuspid regurgitation jet (TRJ) via the pulse wave Doppler velocity method. Systemic inflammatory response syndrome criteria (SIRS) were also evaluated based on the clinical and hematological findings in response to lobectomy and pneumonectomy. Following lobectomy and pneumonectomy, we predominantly detected atrial fibrillation and varying degrees of atrioventricular block (AVB). Dogs that died within seven days of the lobectomy (n = 2) or pneumonectomy (n = 1) had complete AVB. Preoperative right atrial, right ventricular, and pulmonary artery dimensions increased gradually during the 30 days (p<0.05) following pneumonectomy, but did not undergo significant changes during that same period after lobectomy. Mean PASP was 56.0 +/- 4.5 mmHg in dogs having significant TRJ after pneumonectomy. Pneumonectomy, but not lobectomy, could lead to increases (p<0.01) in the SIRS score within the first day post-surgery. In brief, it is important to conduct pre- and postoperative cardiac evaluation of dogs undergoing lung resections because cardiac problems are a common postoperative complication after such surgeries. In particular, complete AVB should be considered a life-threatening complication after pneumonectomy and lobectomy. In addition, pneumonectomy appears to increase the likelihood of pulmonary hypertension development in dogs.
Animals ; Atrial Fibrillation/diagnosis/veterinary ; Atrioventricular Block/diagnosis/*veterinary ; Blood Pressure/physiology ; Dogs ; Echocardiography/veterinary ; Electrocardiography/veterinary ; Pneumonectomy/adverse effects/*veterinary ; Postoperative Care/methods/*veterinary ; Postoperative Complications/diagnosis/*veterinary ; Preoperative Care/methods/*veterinary ; Systemic Inflammatory Response Syndrome/diagnosis/etiology/veterinary ; Tricuspid Valve Insufficiency/diagnosis/etiology/veterinary