2.Definition of inflammatory subtypes of chronic rhinosinusitis with nasal polyp and asthma.
Dawei WU ; Min ZHANG ; Qian SONG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(16):1495-1500
Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is a common clinical refractory airway disease. Comprehensive treatment of nasal endoscopic surgery including nasal endoscopic surgery and medication, which can significantly improve nose-pulmonary symptoms and make sinusitis and asthma easier to be controlled by medication, has certain superiority. But the existence of disease heterogeneity of CRSwNP with asthma causes different reactions to the current treatment, which manifests as parts of polyps and asthma easy to recur and difficult to control. According to the research recently, the study of the heterogeneity of airway diseases, for example endotype, is a hot area of research. Endotype is a subtype of a condition, which is defined by a distinct functional or pathobiological mechanism. This is distinct from a phenotype, which is any observable characteristic or trait of a disease. Different Inflammatory subtypes often represent different pathophysiology and even different pathogenesis. The concept of inflammatory subtypes of airway diseases provides a new perspective for studies of airway diseases of endotype and the mechanism of combined airway diseases. This review summarizes recent advances in the clinical characterization and treatment of the CRSwNP with asthma. On this basis, we analyze and summarize the heterogeneity of CRSwNP and asthma separately from the perspective of inflammatory subtypes. Then according to the concept of the combined airway diseases and the common pathogenesis, we put forward the definition of inflammatory subtypes of the CRSwNP with asthma and preliminarily discuss the method of the definition.
Asthma
;
complications
;
Chronic Disease
;
Endoscopy
;
Humans
;
Nasal Polyps
;
complications
;
Rhinitis
;
complications
;
diagnosis
;
Sinusitis
;
complications
;
diagnosis
3.Combined airway disease.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(15):713-717
The datas of epidemiological, clinical, and immunopathology demonstrate there is an important link between upper and lower airways. The upper airways diseases including the allergy rhinitis, the professional rhinitis, the sleep apnea and hypoventilation syndrome, nose polyposis (with/without aspirin sensitive), the chronic rhinosinusitis and so on, have an important contacting with lower airways diseases. Understanding how the upper airway does affect the lower airway disease, has the influential role to diagnosis, the treatment and the prognosis. This article made the brief summary on the important relation about among the nose, the paranasal sinus and the lung recent years.
Asthma
;
complications
;
Humans
;
Lung Diseases, Obstructive
;
complications
;
Rhinitis
;
complications
;
Sinusitis
;
complications
4.Allergic Bronchopulmonary Aspergillosis Coupled with Broncholithiasis in a Non-asthmatic Patient.
Won Jung KOH ; Joungho HAN ; Tae Sung KIM ; Kyung Soo LEE ; Hye Won JANG ; O Jung KWON
Journal of Korean Medical Science 2007;22(2):365-368
Allergic bronchopulmonary aspergillosis (ABPA), an asthmatic disease, is caused primarily by hypersensitivity to Aspergillus species. ABPA is rarely observed in the absence of asthma, which is, in fact, the principle criterion for its diagnosis. Here, we report the case of a 36-yr-old woman without a history of bronchial asthma, who manifested a localized pneumonic consolidation, coupled with broncholithiasis. Pathologic examinations of bronchoscopic biopsy specimens and resected surgical specimens revealed features typical of ABPA. This is a very rare case of ABPA coupled with broncholithiasis in a non-asthmatic individual.
Lithiasis/*complications/*diagnosis
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Humans
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Female
;
Bronchial Diseases/*complications/*diagnosis
;
Asthma
;
Aspergillosis, Allergic Bronchopulmonary/*complications/*diagnosis
;
Adult
6.Management of conscious sedation in dental treatment for asthma patients.
Acta Academiae Medicinae Sinicae 2010;32(3):357-360
Asthma, often begins in childhood, can affect dental health. In return, dental treatment and dental anxiety can lead to an acute asthmatic attack. This article reviews the potential influence of asthma on dental treatment and dental medications and specifically describes the modes of dental conscious sedation in asthmatic patients.
Anesthesia, Dental
;
methods
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Asthma
;
etiology
;
Dental Anxiety
;
complications
;
Humans
7.Diagnosis and treatment of pediatric allergic rhinitis with comorbid diseases except asthma and upper airway cough syndrome.
Ze-Zhang TAO ; Rong-Guang WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2011;46(1):23-25
Asthma
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Child
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Cough
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Humans
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Rhinitis, Allergic, Perennial
;
complications
;
diagnosis
;
therapy
9.The eosinophilic otitis media's research progress.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(17):1577-1580
The eosinophilic otitis media(EOM) is an intractable disease characterized by the presence of a highly viscous yellow effusion with extensive accumulation of eosinophils in the middle ear; granulation tissue can been discovered in the middle ear cavity; most of patients have association with bronchial asthma; resist to conventional treatment for otitis media; EOM patients show gradual deterioration of hearing and sometimes become deaf suddenly; effective treatment involves use of topical and oral steroids. This article summarizes the progress of the EOM's diagnosis and treatment.
Asthma
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complications
;
Ear, Middle
;
physiopathology
;
Eosinophilia
;
pathology
;
Eosinophils
;
Hearing Loss
;
complications
;
Humans
;
Otitis Media
;
pathology
10.Approaching chronic cough.
Vijo POULOSE ; Pei Yee TIEW ; Choon How HOW
Singapore medical journal 2016;57(2):60-63
Chronic cough is one of the most common reasons for referral to a respiratory physician. Although fatal complications are rare, it may cause considerable distress in the patient's daily life. Western and local data shows that in patients with a normal chest radiograph, the most common causes are postnasal drip syndrome, postinfectious cough, gastro-oesophageal reflux disease and cough variant asthma. Less common causes are the use of angiotensin-converting enzyme inhibitors, smoker's cough and nonasthmatic eosinophilic bronchitis. A detailed history-taking and physical examination will provide a diagnosis in most patients, even at the primary care level. Some cases may need further investigations or specialist referral for diagnosis.
Asthma
;
complications
;
diagnosis
;
Chronic Disease
;
Cough
;
diagnosis
;
etiology
;
Diagnosis, Differential
;
Gastroesophageal Reflux
;
complications
;
diagnosis
;
Humans