To develop a new evidence-based diagnosis,treatment guideline for rheumatoid arthritis (RA) in China.A multidisciplinary guideline development group was established.The grading of recommendations assessment,development and evaluation (GRADE) system was used to rate the quality of evidence and the strength of recommendations.Recommendations were derived from evidence body,the balance of benefits and harmsand patient's values and preferences.The guideline development group developed 10 recommendations for the diagnosis and treatment of RA.The guideline covered the classification criteria,disease activity monitoring and assessing,antirheumatic drugs (DMARDs) and glucocorticoids with treat-to-target approach of RA.This rheumatoid arthritis guideline was intended to serve as a tool for clinicians and patients for best decisions-making in China.

Consensus ; Female ; Humans ; Male ; Migraine Disorders ; diagnosis ; epidemiology ; metabolism ; Vertigo ; diagnosis ; epidemiology ; metabolism ; Vestibular Diseases ; diagnosis ; epidemiology ; metabolism

Multiple drug use is very common in the elderly， which will significantly increase drug interactions and adverse drug reactions. Cardiovascular disease complicated with neuropsychiatric disease is the most common multi-disease comorbidity among the elderly， and it is also one of the disease combinations involving the most multiple drug use. In order to reduce the adverse clinical outcomes of the elderly in China， Chinese Society of Clinical Pharmacy of Chinese Medical Association organized relevant experts to develop Expert Consensus on Risk Prevention and Control of Multiple Drug Use in Elderly Patients with Cardiovascular Diseases and Neuropsychiatric Diseases in China by using foreign drug use risk assessment tools and combining relevant evidence-based results， and further promote its application in clinical disease treatment practice to reduce the adverse clinical outcomes of the elderly in China.

胸壁肿瘤是胸外科领域常见的肿瘤类型，由于其涉及的组织器官和病理类型多样，包括骨、软组织、血液系统等多个系统，诊断和治疗方式也有所区别。对于大部分胸壁肿瘤而言，手术是其主要的治疗方式，术后造成的大范围胸壁缺损又需要进行胸壁重建。近年来，随着外科技术和植入器械的发展，胸壁肿瘤切除手术和胸壁重建手术也发生了巨大的变化。目前临床中可选择的重建材料和方法众多，但是尚缺乏高级别临床证据对各种胸壁重建技术和重建材料进行比较。胸壁重建的手术方式主要依据术者的经验和个人倾向进行选择，如何正确合理使用重建材料尚无明确规范。本共识基于此目的由部分中国胸外科专家共同制定。

‍Liver cirrhosis （LC） is the terminal pathological stage of various chronic liver diseases and is characterized by chronic inflammation， diffuse fibrosis， pseudolobular formation， and portal-systemic collateral circulation， which belongs to the category of jaundice， hypochondriac pain， and abdominal distension in traditional Chinese medicine. At present， there is still a lack of specific clinical treatment methods， and integrated traditional Chinese and Western medicine therapy can effectively delay the progression of LC. Based on the principle of evidence-based medicine and with reference to the summary of recent clinical practice and the latest guidelines and expert consensus published in China and globally， the guidelines in this article are formed by objectively evaluating the evidence of integrated traditional Chinese and Western medicine diagnosis and treatment of LC and extensively soliciting the opinions of experts in the fields of traditional Chinese medicine， clinical medicine， and clinical epidemiology， so as to provide a reference for integrated traditional Chinese and Western medicine diagnosis and treatment of LC in clinical practice.

The incidence of retroperitoneal tumor is low, and treatment is difficult.According to the recent updates of evidence-based medical evidence at home and abroad, the consensus on the standardized treatment of retroperitoneal tumors were discussed including examination and diagnosis , surgical treatment comprehensive treatment, nutrition, rehabilitation, and review and follow-up, etc.
Antineoplastic Agents ; administration & dosage ; adverse effects ; therapeutic use ; China ; Consensus ; Delivery of Health Care ; standards ; Humans ; Practice Guidelines as Topic ; Retroperitoneal Neoplasms ; diagnosis ; drug therapy ; pathology

Hypertension has become a major public health problem in the world. Entrusted by Society of Cardiovascular Diseases, China Association of Chinese Medicine, the experts reached consensus on the diagnosis and treatment of hypertension with traditional Chinese medicine (TCM) based on the theory of TCM syndrome differentiation, evidence-based medicine, review of previous literatures, experience of famous prestigious Chinese physician, and expert consultation. The key pathogenesis, the characteristics of syndrome, and the regularity of medication of traditional famous formulas for hypertension were collected and summarized. This consensus could be used for reference of TCM and integrative medicine doctors.

Pancreatic cancer ranks the fifth leading cause of cancer-related death, while the incidence has increased in the recent years.Although available diagnosis and treatment have failed to significantly improve patients' outcome, some advances have been made along with the understanding of the new concepts from oncology over the past several years.Pancreatic Cancer Committee of Chinese Anti-Cancer Association worked out this latest edition of "The Clinical Practice Guidelines for Pancreatic Cancer(version 2018)" based on current situation to standardize and improve the diagnosis and treatment of pancreatic cancer in China.This guideline shows algorithms for the diagnosis involving classification and staging, the systematic treatment including surgical resection, systemic chemotherapy and radiation therapy, and the whole-course management model for patients with pancreatic cancer.Different from previous consensus, this guideline contains the discussions and recommendations of 19 hot-issues in the clinical practice for pancreatic cancer in a question-oriented form, such as selection of biopsy and specimen sites, clinical diagnostic criteria for pancreatic cancer, assessment of resectable pancreatic cancer, indications and methods of preoperative biliary drainage, application of laparoscopic surgery, effect of expanding resection on patients' outcomes, dissection of group 16(th) lymph node in standard pancreaticoduodenectomy, prognostic value of serum tumor markers, and neoadjuvant therapy in patients with resectable pancreatic cancer, etc.This guideline aims to raise a better comprehensive understanding of the diagnosis and treatment of pancreatic cancer for specialists, and further improving and standardizing the clinical practice in different medical institutions.

OBJECTIVE: To investigate FDA issued lists and guidance on Bioequivalence Recommendations for Specific Products related with Narrow Therapeutic Index Drugs.METHODS: FDA issued lists and Bioequivalence Recommendations for Specific Products related with Narrow Therapeutic Index Drugs was investigated in multiple aspects, including detailed drugs lists, bioequivalence study designs, selection of bioequivalence subjects,analytes to measure,bioequivalence waiver, selection of reference products.RESULTS: Keeping updated lists and Bioequivalence Recommendations for Specific Products relative with Narrow Therapeutic Index Issued by FDA are to further facilitate generic drug product availability and to assist generic pharmaceutical industry with identifying the most appropriate methodology for developing drugs and generating evidence needed to support ANDA approval or reassessment.CONCLUSION: Narrow therapeutic index list and Bioequivalence Recommendations for Specific Products issued by FDA would provide instructive and practical assists to the equivalence assessment of quality and curative effect for generic products in China, since CFDA have not released similar list and guidance on specific narrow therapeutic index.