Pulmonary aspergillosis is the most common disease of fungal infection and has lower infectivity. Pulmonary aspergillosis is classified by aspergilloma, bronchopulmonary aspergillosis, necrotic and invasive aspergillosis. Invasive aspergillosis is found in immune compromised host, immunosuppressive treatment after organ transplantation, anticancerous chemotherapy, blood abnormality, AIDS patients etc. We reported a case of invasive aspergillosis in an immunocompetent host, with review of literatures.
Aspergillosis ; Drug Therapy ; Humans ; Invasive Pulmonary Aspergillosis* ; Organ Transplantation ; Pulmonary Aspergillosis ; Spinal Cord ; Spine* ; Transplants

Aspergillosis ; Humans ; Mucor ; Mucormycosis/drug therapy*

Aspergillosis, Allergic Bronchopulmonary ; diagnosis ; etiology ; therapy ; Humans

Allergic bronchopulmonary aspergillosis is one of major pulmonary fungal diseases. Although it is not a rare in clinical settings,the misdiagnosis rate is high and the treatment effectiveness remains unstable. This article reviews the recent advances in the diagnosis and treatment of this disease.
Aspergillosis, Allergic Bronchopulmonary ; diagnosis ; therapy ; Humans ; Treatment Outcome

Adult ; Aspergillosis ; etiology ; therapy ; Aspergillus fumigatus ; Heart Transplantation ; Humans ; Male

Aspergillosis, Allergic Bronchopulmonary ; diagnosis ; drug therapy ; Child ; Humans ; Male

Most primary spinal abscesses, irrespective of pathogens and anatomical locations, have better prognosis than that of secondary abscesses with spondylitis. We report a 68-year-old man, previously undertaken pulmonary resection due to tuberculosis, presented with paraparesis. Imaging studies showed primary intraspinal abscesses at T-1 and T-3 vertebral levels, semi-invasive pulmonary Aspergillosis and inflammation of the posterior mediastinum. Operative procedure and histopathological examination revealed interdural Aspergillus abscess. Despite chemotherapy, he deteriorated progressively, and spondylitis developed at corresponding vertebrae. He eventually died 6 weeks postoperatively due to pulmonary complication. The authors intended to inform that such an extradural inflammatory lesion of Aspergillus abscess should be treated carefully.
Abscess* ; Aged ; Aspergillosis ; Aspergillus* ; Drug Therapy ; Humans ; Inflammation ; Mediastinitis* ; Mediastinum ; Paraparesis ; Prognosis ; Pulmonary Aspergillosis ; Spine ; Spondylitis* ; Surgical Procedures, Operative ; Tuberculosis

The mortality rate of the invasive pulmonary aspergillosis to be able to developed during chemotherapy induced myleosuppressionin is high in hematologic malignancy patients despite antifungal treatment. Effective antifungal treatment combined with operation can decrease the mortaligy rate of the invasive pulmonary aspergillosis. Recently, we experienced the successful management of the two cases of invasive pulmonary aspergillosis in acute lymphoblastic leukemia through effective antifungal treatment and surgical resection. We report this cases with review of literature.
Drug Therapy ; Hematologic Neoplasms ; Hematology ; Humans ; Invasive Pulmonary Aspergillosis* ; Mortality ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Pulmonary Aspergillosis

Aspergillosis ; diagnosis ; drug therapy ; Child, Preschool ; Female ; Humans ; Infant ; Lung Diseases, Fungal ; diagnosis ; drug therapy ; Male

Child ; Guidelines as Topic ; Humans ; Invasive Pulmonary Aspergillosis ; diagnosis ; therapy ; Lung Diseases, Fungal ; diagnosis ; microbiology ; therapy