1.A case of allergic bronchopulmonary aspergillosis shown as bilateral pulmonary masses.
Won Ki KO ; Seung Won CHOI ; Jae Min PARK ; Gang Hyun AHN ; Se Kyu KIM ; Joon CHANG ; Sung Kyu KIM ; Won Young LEE ; Kyu Ok CHOE ; Dong Hwan SHIN
Tuberculosis and Respiratory Diseases 1999;46(2):260-265
The first case of allergic bronchopulmonary aspergillosis(ABPA) was reported by Hinson, et al. in 1952. This was followed by a number of significant description of the disorder. Although typical ABPA initially presents with asthma, fleeting pulmonary infiltrates, and marked eosinophilia, there are many other ways in which the disease may be first manifested. Common radiologic findings in ABPA include pulmonary infiltrates, atelectasis, emphysema, fibrosis, lobar shrinkage with hilar elevation, cavitation, pneumothorax, aspergilloma and central bronchiectasis. We experienced a case of allergic bronchopulmonary aspergillosis presenting rare radiologic finding of bilateral pulmonary masses in chest radiography. With oral corticosteroid treatment, the size of both pulmonary masses was decreased significantly and his asthmatic symptoms were improved.
Aspergillosis, Allergic Bronchopulmonary*
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Asthma
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Bronchiectasis
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Emphysema
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Eosinophilia
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Fibrosis
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Pneumothorax
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Pulmonary Atelectasis
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Radiography
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Thorax
2.Surgical Treatment of Pleural Aspergillosis: a case report.
Hyun Woong YANG ; Jong Bum CHOI ; Soon Ho CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(5):544-547
We have experienced a case of pleural aspergillosis. A 50 year old female complained of malaise, anorexia, coughing with sputum, and right sided pleuritic chest pain of two weeks' duration. About ten years ago, she had been treated for pulmonary tuberculosis with medication. Chest radiography showed right pyopneumothorax with cavitation in the right upper lung and Chest computed tomography revealed right loculated pyopneumothorax with cavity formation suggesting bronchopleural fistula. Decortication and wedge resection with pleurectomy were performed. The postoperative course was satisfactory and has been in good condition up to now. Pleural aspergillosis is a very rare and potentially life-threatening disease, but we have had good results without significant complications by treatment with systemic antifungal drugs and surgical operation.
Anorexia
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Aspergillosis*
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Chest Pain
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Cough
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Female
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Fistula
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Humans
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Lung
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Middle Aged
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Radiography
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Sputum
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Thorax
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Tuberculosis, Pulmonary
3.A Case of chronic necrotizing pulmonary aspergillosis with pulmonary artery aneurysm.
Hwi Jong KIM ; Hyo Young CHUNG ; Soo Hee KIM ; Ji Chul YUN ; Jong Deog LEE ; Young Sil HWANG
Tuberculosis and Respiratory Diseases 2000;49(1):105-110
Pulmonary aspergillosis is classified as a saprophytic, allergic, and invasive disease. Chronic necrotizing pulmonary aspergillosis is categorized as an invasive pulmonary aspergillosis. Most invasive pulmonary aspergillosis have acute and toxic clinical features but chronic necrotizing pulmonary aspergillosis is characterized by a sub-acute infection, most commonly seen in patients with altered local defense system from preexisting pulmonary disease of in mild immunocompromised patients. Pulmonary artery aneurysm due to this infection is termed as a mycotic aneurysm, etiology of which are tuberculosis, syphilis, bacteria and fungus. We report a case chronic necrotizing pulmonary aspergillosis complicating pulmonary aneurysm is a 62 year-old man who was presented with cough, sputum, and fever. Chest radiographs showed a rapid, progressive cavitary lesion and pulmonary artery aneurysm. Angioinvastion of aspergillus was revealed by pathology after operative removal of left upper lobe containing the pulmonary artery aneurysm. He was treated with itraconazole.
Aneurysm*
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Aneurysm, Infected
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Aspergillus
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Bacteria
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Cough
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Fever
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Fungi
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Humans
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Immunocompromised Host
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Invasive Pulmonary Aspergillosis*
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Itraconazole
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Lung Diseases
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Pathology
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Pulmonary Artery*
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Pulmonary Aspergillosis
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Radiography, Thoracic
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Sputum
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Syphilis
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Tuberculosis
4.Aspergillosis of the paranasal sinuses: diagnostic significance of the computed tomography.
Joon KWON ; Kee Hyun PARK ; Soon Il PARK ; So Young JIN
Yonsei Medical Journal 1989;30(3):294-297
Aspergillosis of the paranasal sinuses appears to be relatively rare in occurrence, but there is a growing incidence of it in accordance with the increasing use of antibiotics, steroid hormones, anticancer drugs, and radiation therapy. We have seen 15 cases of aspergillosis of the paranasal sinuses in which computed tomography (CT) was helpful for diagnosis. The characteristic feature of CT findings was the intermixture of high and low density areas in the affected paranasal sinuses, apparently caused by increased X-ray absorption due to calcification. These findings indicate that CT is useful in the preoperative diagnosis of aspergillosis of the paranasal sinuses.
Adult
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Aspergillosis/*radiography
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Female
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Human
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Male
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Middle Age
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Paranasal Sinus Diseases/*radiography
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Paranasal Sinuses/*radiography
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Retrospective Studies
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*Tomography, X-Ray Computed
5.Aspergillosis of the paranasal sinuses: diagnostic significance of the computed tomography.
Joon KWON ; Kee Hyun PARK ; Soon Il PARK ; So Young JIN
Yonsei Medical Journal 1989;30(3):294-297
Aspergillosis of the paranasal sinuses appears to be relatively rare in occurrence, but there is a growing incidence of it in accordance with the increasing use of antibiotics, steroid hormones, anticancer drugs, and radiation therapy. We have seen 15 cases of aspergillosis of the paranasal sinuses in which computed tomography (CT) was helpful for diagnosis. The characteristic feature of CT findings was the intermixture of high and low density areas in the affected paranasal sinuses, apparently caused by increased X-ray absorption due to calcification. These findings indicate that CT is useful in the preoperative diagnosis of aspergillosis of the paranasal sinuses.
Adult
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Aspergillosis/*radiography
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Female
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Human
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Male
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Middle Age
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Paranasal Sinus Diseases/*radiography
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Paranasal Sinuses/*radiography
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Retrospective Studies
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*Tomography, X-Ray Computed
6.A case of endobronchial aspergilloma.
Joo Seong KIM ; Yumie RHEE ; Shin Myung KANG ; Won Ki KO ; Young Sam KIM ; Jun Gu LEE ; Jae Min PARK ; Se Kyu KIM ; Sung Kyu KIM ; Won Young LEE ; Joon CHANG
Yonsei Medical Journal 2000;41(3):422-425
Pulmonary aspergillosis may be classified under three categories, depending upon whether the host is atopic or immunocompromised: invasive aspergillosis, allergic bronchopulmonary aspergillosis (ABPA) or aspergilloma. However, it is not always possible to effectively categorize this disease. We experienced a case of endobronchial aspergilloma, which was difficult to categorize, in a healthy male patient. The chest X-ray and computed tomography showed an ill-defined nodule mimicking lung cancer. Fiberoptic bronchoscopy revealed an aspergilloma without cavity formation in the left lower laterobasal segmental bronchial orifice. The aspergilloma was removed and the patient's symptoms were relieved. We present this unusual case with a review of the literature.
Adult
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Aspergillosis, Allergic Bronchopulmonary/pathology
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Aspergillosis, Allergic Bronchopulmonary/diagnosis*
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Bronchi/pathology
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Bronchoscopy
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Case Report
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Diagnosis, Differential
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Fiber Optics
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Human
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Lung Neoplasms/radiography
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Male
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Radiography, Thoracic
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Tomography, X-Ray Computed
7.Endobronchial Aspergilloma: Report of 10 Cases and Literature Review.
Jeong Eun MA ; Eun Young YUN ; You Eun KIM ; Gi Dong LEE ; Yu Ji CHO ; Yi Yeong JEONG ; Kyoung Nyeo JEON ; In Seok JANG ; Ho Cheol KIM ; Jong Deok LEE ; Young Sil HWANG
Yonsei Medical Journal 2011;52(5):787-792
PURPOSE: A retrospective investigation of the clinical and radiologic features as well as the bronchoscopic appearance was carried out in patients with endobronchial aspergilloma. MATERIALS AND METHODS: Ten patients with endobronchial aspergilloma diagnosed by bronchoscopy and histological examination were identified at the Gyeongsang University Hospital of Korea, from May 2003 to May 2009. RESULTS: The patients included 9 men and 1 woman, and the age of the patients ranged from 36 to 76 (median, 58 years). The associated diseases or conditions were: previous pulmonary tuberculosis in 7 patients, lung cancer in 2 patients, pulmonary resection in 1 patient, and foreign body of the bronchus in 1 patient. The chest radiologic finding showed fibrotic changes as a consequence of previous tuberculosis infection in 6 patients and a mass-like lesion in 2 patients. Two patients had a co-existing fungus ball, and an endobronchial lesion was suspected in only 2 patients on the CT scan. The bronchoscopic appearance was a whitish to yellow necrotic mass causing bronchial obstruction in 7 patients, foreign body with adjacent granulation tissue and whitish necrotic tissue in 1 patient, whitish necrotic tissue at an anastomosis site in 1 patient, and a protruding mass with whitish necrotic tissue in 1 patient. CONCLUSION: An endobronchial aspergilloma is a rare presentation of pulmonary aspergilosis and is usually incidentally found in immunocompetent patients with underlying lung disease. It usually appears as a necrotic mass causing bronchial obstruction on bronchoscopy and can be confirmed by biopsy.
Adult
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Aged
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Bronchi/pathology
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Bronchography
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Bronchoscopy
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Female
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Humans
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Male
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Middle Aged
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Pulmonary Aspergillosis/*diagnosis/pathology/radiography
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Republic of Korea
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Retrospective Studies
8.Two Cases of Pleural Aspergillosis.
Hyeok SHIM ; Jeong Hyun PARK ; Sei Hoon YANG ; Eun Taik JEONG
Tuberculosis and Respiratory Diseases 2001;51(1):70-75
Aspergillosis refers to an infection with any species from the genus Aspergillus. Pleural aspergillosis is an uncommon disease with less than 30 cases having been reported in the literature since 1958. The etiologic factors for this aspergillosis are preexisting pulmonary tuberculosis, bronchopleural fistula, pleural drainage, and a lung resection. Surgical removal of the aspergillus-infected pleura is the main treatment for managing this disease. We have experienced two cases of pleural aspergillosis as a complication of a preexisting chronic empyema. The chest radiographs showed a pyopneumothorax with cavitation and the chest computed tomographic scans revealed a loculated pyopneumothorax with cavity formation suggesting a bronchopleural fistula. A grossly purulent fluid was extracted by thoracentesis, and Aspergillus fumigatus was grown from a fungus culture of the fluid. A decortication, wedge resection with a pleurectomy and a pleuropneumonectomy were performed. The postoperative course was satisfactory and the patients have been in good condition up to now. Pleural aspergillosis is a very rare and potentially life-threatening disease. However, good result without significant complication were obtained by treatment with systemic antifungal agents and surgical removal.
Antifungal Agents
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Aspergillosis*
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Aspergillus
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Aspergillus fumigatus
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Drainage
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Empyema
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Fistula
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Fungi
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Humans
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Lung
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Pleura
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Radiography, Thoracic
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Thorax
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Tuberculosis, Pulmonary