1.A panoramic view on phytochemical, nutritional, ethanobotanical uses and pharmacological values of Trachyspermum ammi Linn
Asif Muhammad Hafiz ; Sultana Sabira ; Akhtar Naveed
Asian Pacific Journal of Tropical Biomedicine 2014;(z2):545-553
Trachyspermum ammi Linn. (T. ammi) is an aromatic, grassy, annual plant belonging to Umbelliferae family which grows in the east of India, Pakistan, Iran, and Egypt. T. ammi has been used traditionally to treat arthritis, colic, diarrhea and gastrointestinal problems. In addition to these medicinal uses, T. ammi continues to be valued around the world as an important cooking spice and is believed to relief the common cold, flu-like symptoms, headaches, and even painful menstrual periods. These multiple uses can be explained by its several active compounds. The phytochemical studies on T. ammi seeds have revealed the presence of alkaloids, steroids, fixed oils, glycosides, tannins, saponin and flavonoids, cumene, thymene, amino acids and dietary fiber essential oils like thymol, c-terpinene, p-cymene. Several pharmacological studies on anti-tussive effect, inhibitory effect on histamine (H1) receptors, antihypertensive, antispasmodic, bronchodilator, hepato-protective, analgesic, anti-inflammatory, antioxidant and anti mutagenic activities of T. ammi seed extracts have been reported in the literature. The present review is therefore, an effort to give a detailed survey of the literature on traditional, phytochemical and pharmacological properties of T. ammi.
2.Prevalence of Ascaridia galli in white leghorn layers and Fayoumi-Rhode Island red crossbred flock at government poultry farm Dina, Punjab, Pakistan
Hafiz Allah Bachaya ; Muhammad Asif Raza ; Muhammad Ashraf Anjum ; Imran Ahmad Khan ; Abdul Aziz ; Zahid Manzoor ; Shaukat Hussain Munawar
Tropical Biomedicine 2015;32(1):11-16
Poultry farming not only provides high nutritious food but also creates employment
opportunity for rural masses. Documented evidences elaborates that helminth parasitism is
most deciduous problem of chickens especially in developing world. Ascaridia (A.) galli, a
nematode of small intestine, has been considered as the most common and important parasite
of chicken. The present study was carried out to investigate prevalence and severity of A.
galli in White Leghorn layers (housing type: battery cage and deep litter, 50 each) and
Fayoumi-Rhode Island Red crossbred (male and female: 50 each) flock rearing at Government
Poultry Farm, Dina, Punjab, Pakistan. Two hundred faecal samples were examined by using
standard parasitological and McMaster egg counting technique. The overall prevalence was
24.5% at farm, 13% in White leghorn layer (battery cage=2%, deep litter=24%) and 36% in
Fayoumi-Rhode Island Red (male=34%, female=38%). It was also observed that White leghorn
layer rearing in deep litter had more severe infection (EPG=1920) of A. galli compare with
battery cages birds (EPG=500). Parasite prevalence was significantly related with sex (P<0.05)
in Fayoumi-Rhode Island Red and male birds had less number of average parasites (0.34±0.47)
as compared to females (0.38±0.490). Additionally, female birds were under serious threat of
infection (EPG=2270) compared with its counterpart (EPG=1250). Given the high infection
rates, particular attention should be paid to management and provision of feed supplement to
White leghorn layer housing in deep litter and female bird of Fayoumi-Rhode Island Red
crossbred.
3.Assessment of biochemical and antioxidative status in patients suffering from dengue fever.
Mahmood RASOOL ; Arif MALIK ; Khalid Mahmud KHAN ; Muhammad Saeed QURESHI ; Beenish SHABBIR ; Sara ZAHID ; Muhammad ASIF ; Abdul MANAN ; Sana RASHID ; Saima Rubab KHAN ; Hafiz Muhammad ARSALAN ; Rabail ALAM ; Mahwish AROOJ ; Mahmood Husain QAZI ; Adeel Gulzar Ahmed CHAUDHARY ; Adel Mohammed ABUZENADAH ; Mohammed Hussain AL-QAHTANI ; Sajjad KARIM
Journal of Huazhong University of Science and Technology (Medical Sciences) 2015;35(3):411-418
A multi-centred study was designed to collect dengue epidemiologic data from government and registered private hospitals/clinics and maintained archive of frozen specimens in bio-bank to be used for future dengue epidemic control program, and assess the epidemiology of dengue fever (DF) by evaluating biochemical and oxidative status of patients. ELISA IgM antibodies test was done to confirm DF. From August 2010 to December 2011, 101 confirmed blood samples of DF patients referred to pathology lab of Jinnah Hospital Lahore were subjected to the epidemiologic assessment by evaluating the biochemical and physiological indices and alterations of circulating antioxidants. Clinical features of DF patients and effect of fever on blood components and serum proteins of liver were recorded. The hospital stay in DF, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) showed significant difference. Significant increases in serum alanine amino transferase (ALT) (P=0.000), aspartate amino transferase (AST) (P=0.000), alkaline phosphatase (ALP) (P=0.000), malondialdehyde (MDA) along with significant decreases in total protein (TP) (P=0.000), reduced glutathione (GSH) (P=0.000), superoxide dismutase (SOD), catalase (CAT) (P=0.000), and sialic acid contents (P=0.016) were observed. A positive correlation existed between bound sialic acid levels, liver enzymes and circulating antioxidants (r=0.656, P=0.016). In the present study, alterations of circulating antioxidants in DF suggest that DF might be a metabolic response to an acute, self-limiting tropical viral infection, and a consequence of the viral inflammatory process.
Adult
;
Antioxidants
;
metabolism
;
Biomarkers
;
blood
;
China
;
Dengue
;
classification
;
diagnosis
;
metabolism
;
Diagnosis, Differential
;
Female
;
Humans
;
Immunoglobulin M
;
metabolism
;
Male
;
Middle Aged
;
Young Adult