1.Effect of fan for dyspnea in terminally ill cancer patients:Case series study
Jun Kako ; Asuko Sekimoto ; Asao Ogawa ; Mitsunori Miyashita
Palliative Care Research 2015;10(1):147-152
The effects of a fan to reduce dyspnea have been evaluated in several trials worldwide, however, there has been no clinical report in terminal cancer patients in Japan. We conducted a retrospective chart review to examine whether a fan is useful for dyspnea in terminally ill cancer patients. We reviewed medical and nursing records and selected all patients(n=9)who received a fan from July 2013 and January 2014. The primary outcome measure was a decrease dyspnea measured by a visual analogue scale(VAS;0=no shortness of breath, 100=worst shortness of breath). There was a significant difference in the VAS score after treatment with the fan(40.2±11.8 versus 15.6±14.9, P=0.004). Our results suggest that a fan may help in reduces the sensation of dyspnea in patients with terminal cancer. Future prospective study is needed.
2.Dementia Provision for Elderly Cancer Patients in Designated Regional Cancer Centers
Yusuke Kanno ; Hiroyuki Nobata ; Yoshio Iwata ; Kensuke Higa ; Nanao Sayama ; Yasuko Uchimura ; Kiyoko Otani ; Kana Toyonaga ; Mitsunori Miyashita ; Asao Ogawa
Palliative Care Research 2017;12(1):116-124
The aim of this study was to investigate the dementia provision for elderly cancer patients in designated regional cancer centers. A survey was mailed to 389 designated regional cancer centers from February to June, 2015. A total of 188 facilities responded (response rate: 48.3%). 5.3% of the respondents used two manuals (on basic dementia care and the behavioral and psychological symptoms of dementia) to check whether these centers were following appropriate measures. About 50% of the respondents performed dementia assessments by the primary care team. 29.3% of the respondents maintained the system of the education and training of dementia care. Therefore, dementia provision for elderly cancer patients in designated regional cancer centers needs to improve the education of dementia care.
3.Exploratory Research on Factors Related to Difficulty in Decision Making in Elderly Patients with Cancer
Kei HIRAI ; Asayo YAMAMURA ; Nanami SUZUKI ; Asao OGAWA
Palliative Care Research 2021;16(1):27-34
Objective: The purpose of this study is to clarify the characteristics of cases where decision-making is difficult and how the medical staff can deal with them in the medical field. Method: Seven oncology physicians were interviewed. The survey items include cases where decision-making is difficult, how to deal with them, and decision support. Category analysis was performed based on verbatim records. Results: First, the cases where decision-making is difficult were divided into two categories: patient factors and environmental factors. The former is further divided into two subcategories: “personal factors” include personality and, intellectual ability and “factors due to diseases and aging” that included flailing of body parts and dementia. Further, there were three categories of medical staff’s strategies: assessment, response skills, and environmental approach. Discussion: In providing information to patients, it is necessary to respond according to the patient’s intellectual state environmental factors to promote understanding. Specifically, it is effective to use patient-specific explanations, target planning, and nudges.
4.Effectiveness of a Decision Support Training Program for Health Care Professionals
Kei HIRAI ; Asayo YAMAMURA ; Nanami SUZUKI ; Asao OGAWA
Palliative Care Research 2023;18(3):183-191
Purpose: In today’s medical field, it is an essential quality competency for staff to not only recognize the importance of patient decision-making and the skills to support it, but also implement it. This study aimed to establish a training program on decision support for healthcare professionals and examine its effectiveness. Method: We conducted the training at a medical institution and conducted a questionnaire survey at two points before and after the training. A total of 88 nurses and doctors participated in the survey. Result: We developed a two-hour training on the knowledge and skills needed for decision support. Questionnaire results showed improvements in literacy and efficacy before and after the training. Discussion: It was confirmed that the training led to an in-depth understanding of the participants’ decision support, and increased the sense of efficacy in their daily work, particularly through responding to patients according to patients’ cognitive and physical assessments, and in actively supporting those who have difficulty in making decisions. There were references to the significance of re-learning and the possibility of applying the training to difficult situations in participants comments. In the future, it is necessary to study decision support with reference toco-operation in the medical field where collaboration among multiple professions is indispensable.
5.Pain Management of Community-dwelling Older Adults with Dementia Practiced by Visiting Nurses
Chiaki ANDO ; Yusuke KANNO ; Shoko SUZUKI ; Fumiyo TAKAHASHI ; Asao OGAWA
Palliative Care Research 2019;14(2):151-157
To clarify nursing practices in pain management of community-dwelling older adults with dementia by visiting nurses, we conducted semi-structured interviews with 10 visiting nurses and analyzed their responses qualitatively and inductively. As a result, 24 subcategories and 8 categories were identified. Visiting nurses were found to conduct pain assessment and assessment based on behavioral changes in usual daily life because of characteristics of health assessment in home care, in which the goal is to comprehensively support clients as living people, in addition to standard pain management of older people with dementia. The results suggest that the viewpoint to integrate information from other professionals and family members and assess daily life comprehensively is important, and some mechanism to facilitate multidisciplinary information sharing is required. When visiting nurses were unsure of whether a patient is in pain, they evaluated the patient’s pain on the basis of behavioral changes in his or her normal daily life after medication or nondrug treatment. A nationwide survey is necessary for further clarification.
6.The Effect of Continuous Subcutaneous Infusion of Chlorpromazine on Refractory Delirium in Advanced Cancer: Retrospective Study
Daisuke KIUCHI ; Takayuki HISANAGA ; Shingo HAGIWARA ; Katsuya ABE ; Akira OSADA ; Kenjirou HIGASHI ; Yuki SUGIHARA ; Aya NUMATA ; Ko HISAHARA ; Tatsuya MORITA ; Asao OGAWA ; Yasuo SHIMA
Palliative Care Research 2019;14(3):169-175
Context: Delirium in cancer is often difficult to control and refractory when haloperidol is invalid which is considered standard therapy. We need second and subsequent-line therapy to reduce hyperactivity and not to over-sedation for refractory delirium. Objectives: To investigate the efficacy and safety of continuous subcutaneous infusion chlorpromazine on delirium refractory to first-line antipsychiatric medications in advanced cancer palliative care setting. Method: The study population consisted of patients who received continuous subcutaneous infusion chlorpromazine for delirium at two certified PCU. Primary endpoint was the proportion of patients who showed improvements in delirium severity by Delirium Rating Scale Revised 98 score of less than 13 or decrease from baseline and maintained the ability to communicate coherently by Communication Capacity Scale Item-4 score of 2 or less. Secondary outcome were the Nursing Delirium Screening Scale subscale score, and injection site reactions evaluated according to the Common Terminology Criteria for Adverse Events. These outcome measures were assessed at baseline, 48 hours and 7 days after the start of the study. Result: Among eighty-four patients, sixty were positive responders (71.4%, 95% CI [61–80]). The mean CCS Item-4 scores significantly decreased from the baseline value of 1.48 (range 0–3) to 1.03 (range 0–3) at post-treatment (p<0.001). Grade 2 or higher injection site reactions were observed in 1 patient (1.2%, 95% CI [0–7]). Conclusion: Our study suggested that continuous subcutaneous infusion chlorpromazine could improve refractory delirium symptoms and patients’ communication capabilities. Although most of the skin disorders observed in association with chlorpromazine were mild, their incidence rates were relatively high, suggesting the need for careful monitoring.
7.Terminal Anguish among Delirious Patients with Advanced Cancer: A Multicenter, Prospective, Observational Study
Natsuki KAWASHIMA ; Takayuki HISANAGA ; Jun HAMANO ; Isseki MAEDA ; Kengo IMAI ; Akihiro SAKASHITA ; Yoshihisa MATSUMOTO ; Keiichi UEMURA ; Takuya ODAGIRI ; Asao OGAWA ; Kazuhiro YOSHIUCHI ; Satoru IWASE
Palliative Care Research 2019;14(3):237-243
Objective: This study aimed to reveal the prevalence and characteristics of anguish among delirious patients with advanced cancer receiving specialized palliative care services. Methods: We conducted a subanalysis of a multicenter, prospective, observational study at 14 inpatient palliative care units and 10 general wards that offered psycho-oncology consultation service in Japan. We consecutively enrolled the patients with advanced cancer who were diagnosed with delirium and prescribed antipsychotics. Palliative care specialists decided whether patients suffered from anguish or not. We assessed patients’ background and severity of delirium with the Delirium Rating Scale-Revised (DRS-R-98). Results: Of 818 enrolled patients, 99 (12.1%) suffered from anguish. We observed a significant difference in the mean age (68.9±12.6 vs. 72.1±11.2, p=0.009), prevalence of dementia (2% vs. 10.4%, p=0.005) between patients with anguish and those without anguish. Patients with anguish had lower DRS-R-98 total scores before medication than those without anguish (15.3±8.1 vs. 17.3±7.8, p=0.018), but higher severity score in lability of affect (1.2±0.8 vs 1.0±0.9, p=0.023). Conclusions: The results of this study suggested that patients with anguish tend to be younger, mostly do not have dementia, and have lower delirium severity score but higher score in lability of affect. Nevertheless, further research, investigating appropriate evaluations and medical interventions for patients with anguish is warranted.