1.Rhupus syndrome.
Jae Ki MIN ; Kyoung Ann LEE ; Hae Rim KIM ; Ho Youn KIM ; Sang Heon LEE
The Korean Journal of Internal Medicine 2015;30(1):131-131
No abstract available.
Antirheumatic Agents/therapeutic use
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Arthritis, Rheumatoid/blood/*complications/diagnosis/drug therapy/physiopathology
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Biological Markers/blood
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Drug Therapy, Combination
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Facial Dermatoses/complications/diagnosis
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Female
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Hand Joints/physiopathology/radiography
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Humans
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Immunosuppressive Agents/therapeutic use
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Inflammation Mediators/blood
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Knee Joint/physiopathology/radiography
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Lupus Erythematosus, Systemic/blood/*complications/diagnosis/drug therapy
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Middle Aged
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Syndrome
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Treatment Outcome
2.Successful Treatment of Progressive Rheumatoid Interstitial Lung Disease With Cyclosporine: A Case Report.
Hyun Kyu CHANG ; Wann PARK ; Dae Sik RYU
Journal of Korean Medical Science 2002;17(2):270-273
Treatment of interstitial lung disease (ILD) in rheumatoid arthritis (RA) has been controversial. Although there have been several anecdotal reports on the efficacies of corticosteroids or cytotoxic agents such as methotrexate, cyclophosphamide, azathioprine, and D-penicillamine for the treatment of ILD associated with RA, no controlled studies have been performed. To date, corticosteroids have been a central agent for the treatment of this disease, but their effects are partial and temporary in most cases. In addition, the adverse effects of these agents are considerable. On the other hand, limited information is available on the cyclosporine use in ILD associated with RA. We describe a 49-yr old female patient with RA and ILD that had initially responded to high dose prednisolone and cyclophosphamide intravenous pulse therapy, and the lung disease was aggravated with the tapering of prednisolone. After 10 months of follow-up loss, the patient was successfully treated with low dose cyclosporine without high dose corticosteroids.
Anti-Inflammatory Agents/therapeutic use
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Antirheumatic Agents/*therapeutic use
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Arthritis, Rheumatoid/complications/*drug therapy/radiography
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Cyclophosphamide/therapeutic use
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Cyclosporine/*therapeutic use
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Disease Progression
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Female
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Glucocorticoids/therapeutic use
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Humans
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Lung Diseases, Interstitial/complications/*drug therapy/radiography
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Middle Aged
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Prednisolone/therapeutic use
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Treatment Outcome