IntroductionHypertension is a major public health problem with serious medical and financial consequences. Barriers to successful conventional pharmacological treatment include the side effects, out-of-pocket expenses, patient non-compliance and insufficient dosages. The design of the Stop Hypertension with the Acupuncture Research Program (SHARP) trial balanced rigorous clinical trial methodology with principles of TCM.GoalTo treat arterial hypertension by traditional medicines and acupuncture, and determine its effectiveness.Materials and Methodsthe participants had systolic blood pressure (SBP) 140-179 mmHg and diastolic BP (DBP) 90-109 mmHg in the absence of antihypertensive therapy. Following a screening, the participants were randomly divided to one of the following two groups: individualized acupuncture and standardized acupuncture. Standardized acupuncture used a pre-specified set of points. In the other group, each participant received a “prescription” for individualized acupuncture from an acupuncturist who was masked to treatment assignment, and was subsequently treated by an independent acupuncturist. Acupuncture was performed twice a week for 6 weeks.ResultsThe systolic blood pressure reduced statistically significantly through the 2nd, 4th and 6th weeks against the measurements taken at the onset of the treatment. Before the acupuncture therapy, the systolic blood pressure was 159.52 mmHg (95% CI: 156.52-162.51) and it reduced to 147.62 mmHg (95% CI: 147.62-154.22) in the 6th week. Before the acupuncture therapy the DBP was 98.34 mmHg (95% CI: 96.77-99.91). It reduced to 92.56 mmHg (95% CI: 90.80-94.31) at the 6th week. Conclusions: Acupuncture therapy reduced SBP by the mean of 8.6 mmHg and DBP by the mean of 5.78 mmHg.

The increasing proportions of aged persons have been accompanied in the world. NCDs are often associated with older age groups. High blood glucose levels and unhealthy diet increase the risk of or cause most NCDs. In this study we aimed to determine correlation between the older people (60<) blood glucose level and food consumption. 1563 healthy elder people participated in this research. We measured blood glucose level in all subjects at the Nursing school’s Training and Research Center of health science university of Mongolia. Ulaanbaatar city, Orkhon aimag, Khovd aimag, Khentii aimag, Bulgan aimag, Dornogovi aimag, Tov aimags represented urban areas, while the rest of aimags and soums represented rural areas. The questionnaire was used to collect data on respondent’s social-economic status, fruit and vegetable consumption, physical activity, and their causes. In order to assess the diet pattern of the surveyed population, the respondents were asked about frequency of fruit and vegetable consumption, type of oil used in food, and amount of salt consumed daily. Simple regression analysis was performed to shown that significantly positive correlations between blood glucose and salt intake (р<0.001), The other composition are no significantly changes.

Recent years non communicable disease moribidity isincreasing due to broken bone caused by bone rarity and accident. National Trauma Orthopedic Research Center (2009) survey showed that in recent years the number of inpatients broken bone is 30.8% and 60.5% of this people concern tibial fracture. Recovery after bone rarity and bone breakage is important. To aid faster recovery, traditional medicine often used Calcite and Rhodiola rosea. L to cure breakage. It attracts attention that Natural calcite consistsof 10 minerals and almost 64% of calcum. In our study, we used masculine calcite from Bayankhongor aimag “ Tsagaanagui”, Altpant which made from Rhodiola rosea basis and 30 rabbits from “Introduction of corporation of traditional medical science, technology” laboratory. We observed rabbits at 2nd, 14th, 28h, 49th, 60thdays controlled with 2 angle projection using Hitachi-TU 51 X ray machine. Also, at the 7th, 28th, 60thdays samples were taken for histopathology analysis. As a result, control group had 10 degree turn as compared to calcite treated group. However both group rabbits were healing fine. In histological analyses callus and endost were fine. Osteoblast structure is fine, osteocite is placed in lacun. Volkmann cannal is seen good.

In recent years medicine faces growing number of bone fractures caused by accident injuries and osteoporosis, which became a big problem. Today in medicine praxis Calcium supplements is widely used, however Lai B, Cervell MJ’s research shows that using calcium during long time conversely bad for stomach. We chose for our research work Calcite known in traditional medicine as bone nutrition contains up to 67% of calcium, attract our attention. Otherwise, elixir subdued calcite also has a treatment action for gastric ulcer and protects stomach. Therefore we made a fracture in a Kriscner wire using Bannarens Einhorn method and at the early stage of fracture healing (2nd and 4th week) started observing the effect of elixir subdued calcite using radiography analyses. At the result, our research showed that callus of the group of rats used elixir subdued calcite are statisticalsignificance more fast than the group which used calcium supplement. However compared to the group used standard rat chow ad libitum, the group which used calcite, curing effect statistically accelerated in 28 days, while in 14 days there were no statistical significant of difference. Finally, result shows that compared to other groups elixir subdued calcite is accelerating the curing effect, but for supervising later or posterior bone healing process there is a requirement of using additional analysis methods.

Fracture healing starts with a hematoma, continues with bone formation, and ends with bone remodeling. We decided to investigate the effects of Jonsh-5 composition on the serum level of TGF-β1 during fracture healing. A Wistar rats were utilized. K- wire was inserted into the femur in a retrograde fashion, and a mid-diaphyseal closed transverse fracture was created using method of Bonnarens & Einhorn (1984). All rats were randomly in three groups. Group 1 (Control group, n=26) was given normal food without any medicine. Group 2,3 ( each group n=26) were administered 0.625 mg calcium supplement and 1.3 g Jonsh-5 composition with normal food. Serum analysis, histological evaluations were performed at days 1, 7, 14 and 28 and after femur fracture according to the criteria proposed by Huo et al. Serum analysis , there was significant difference treatment effect between Group 3 (Jonsh-5 composition) and Groups 1,2 at days 3,7,14 and 28 days after fracture. The histological results demonstrated a significant stimulation of the fracture healing due to group 3 compared to group 1,2 at days 14 and 28 .Under studied conditions this investigation shows that administration of Jonsh-5 accelerate fracture healing process in rat femur

Purpose; To control acupuncture of essential hypertension. Method;The design of the SHARP trial balanced rigorous clinical trial methodology with principles of TCM. Eligible participants had systolic blood pressure 140-179 mm Hg and diastolic blood pressure 90-109 mm Hg in the absence of antihypertensive therapy. Acupuncture was delivered twice a week for 6 weeks.Follow –up visits were every 2 weeks. Result;At weeks 2, 4 and 6 ;both pre-acupuncture and post- acupuncture blood pressure were measured. Those time pre- acupuncture blood pressure decline than post –acupuncture(p<0.0001) . Conclusion;Acupuncture treatment had a significant negative influence reduction blood pressure.

In last years we have produced a combination species from medicinal plants which are used in traditional medicine and has tendentious the increasing of needs and production of plant preparations from natural resources. Although traditional medicine has being increased to be used last years, standardization of them is not sufficient. The standardization is important to ensure the safety, effectiveness and quality of traditional medicine. This research was made with purposes for determining of qualitative and quantitative analyses of biological active substances in the preparation such as Jonsh-5 is utilized to prevent osteoporosis, to accelerate bone ankylose in period of injure. The compositions of the preparation Jonsh-5 are Calcitum, Carduus crispus L. Inula helenium L.Terminalia chebula Retz, Forsutima suspense Thunb. Vahl.In order to succeed the above mentioned aim, we have achieved the following results: 1. The chromatographical method and methodology for the qualitative and quantitative analyses of main compounds in the preparation Jonsh-5 were developed using HPLC. 2. Quantitative analyses of main compounds of the compositions in the preparations were defined by HPLC method. 1.000gr of the preparation Jonsh-5 involves gallic acid 1.11 mg, alantolaktone 1.77 mg.

Jonsh-5 is composed of 5 components including calcite, Cardius crispus, Forsythia suspense, Terminalia Chebula, and Inula helenium. Aim of this study is to examine the effect of traditional drug Jonsh-5 on experimental femur fracture in rats. Jonsh-5 was given to rats for 28 days. Calcium D3-Nycomed (2.5 g/kg) was used for comparison. 2, 14, and 28 days after fracture, serum levels of alkaline phosphatase were determined and fracture healing processes were evaluated by X-ray. Serum level of alkaline phosphatase was 197 u/l before fracture. After 7 days of fracture, alkaline phosphatase level was significantly increased by Jonsh-5 (728 u/l) and there were no statistical differences observed in rats with no treatment (control) and Calcium D3-Nycomed-treated animals. Similar patterns were observed 14 and 21 days after fracture. X-ray images showed that healing process of the bone was significantly increased by Jonsh-5 compare to control and Calcium D3-Nycomed treatment. Jonsh-5 may promote bone healing in rat model of fracture.

In traditional Mongolian Medicine, materials derived from plants, animals, trees, and minerals are processed by traditional technology to improve their effectiveness and safety. One of mineral-based materials is calcite which is widely used in traditional medicine. Mineral contents of calcite: After processing by traditional technology (taming) with enrichment, calcite turns to bright yellow, small soft microcrystals with bitter taste and smell of milk. Moreover it obtains solubility in water. Various macro- and microelements were determined in tamed calcite including Na, Mg, K, Ca, S, Mn, and Fe. Ca takes the major part (64%) of the elements. Crystal size determined by NANOPHOX (PCCS), GmbH, Sympatec apparatus were 115 nm and 124 nm depending on the traditional technology of processing. Crystal structure of calcite in phase shifts was analyzed after burning it in +300º C, +500 º C, +800 º C, +1200 º C, and +1400 º C by using Shimadzu XRD-7000 X-ray diffractometer, HA- 1001, and TTK-450 apparatus. CaCO3 content (84.23%) was higher at +300º C and +500 º C, while CaC2 content (15.77%) was higher at +800 º C, +1200 º C, and +1400 ºC. Effects of calcite on acetic acid-induced gastric ulcer: Gastric ulcer induced by acetic acid in rats was healed completely by tamed calcite within 21 days. Calcite improves bone repair of experimental fracture in rats by increasing Ca and alkaline phosphatase activities. Effects of calcite containing drug Jonsh-5 on experimental femur fracture in rabbits: Jonsh-5 is composed of 5 components including calcite, Cardius crispus, Forsythia suspense, Terminalia Chebula, and Inula helenium. Jonsh-5 increased serum level of alkaline phosphatase after 7 days of fracture. X- ray images showed that healing process of the bone was significantly increased by Jonsh-5 compare to control and Calcium D3-Nycomed treatment. These results were also proved by histological analysis suggesting that Jonsh-5 may promote bone healing in rat model of fracture. Safety of calcite containing drugs: Contents of macro- and microelements, moisture, and substances extractable in water have been determined. Mineral and organic impurities have also been evaluated in Jonsh-5. Bacterial impurity of the drug is within the standard range. Moreover contents of heavy metals such as lead, cadmium, and mercury meat the WHO permeated levels of toxic metals.