Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, is marked by fever, leukocytosis, and painful erythematous papules/plaques resulting from neutrophil migration and accumulation in the dermis. This condition has been associated with underlying hematologic as well as solid malignancies. We describe a unique case of SS in a patient with metastatic papillary follicular thyroid carcinoma and group A streptococcal pharyngitis. The distribution of the patient's SS rash was similar to the rash of neutrophilic dermatosis (pustular vasculitis) of the dorsal hands.
Adenocarcinoma, Follicular ; Dermis ; Exanthema ; Fever ; Hand ; Humans ; Immune System Diseases ; Leukocyte Disorders ; Leukocytosis ; Neutrophils ; Pharyngitis ; Skin Diseases ; Sweet Syndrome ; Thyroid Gland

Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, is marked by fever, leukocytosis, and painful erythematous papules/plaques resulting from neutrophil migration and accumulation in the dermis. This condition has been associated with underlying hematologic as well as solid malignancies. We describe a unique case of SS in a patient with metastatic papillary follicular thyroid carcinoma and group A streptococcal pharyngitis. The distribution of the patient's SS rash was similar to the rash of neutrophilic dermatosis (pustular vasculitis) of the dorsal hands.
Adenocarcinoma, Follicular ; Dermis ; Exanthema ; Fever ; Hand ; Humans ; Immune System Diseases ; Leukocyte Disorders ; Leukocytosis ; Neutrophils ; Pharyngitis ; Skin Diseases ; Sweet Syndrome ; Thyroid Gland

BACKGROUND/AIMS: Data are scarce on endoscopic sedation practices outside the United States and Western Europe, particularly from developing nations. An Internet survey was used to assess endoscopic sedation practices in developing and developed countries. METHODS: Responses to a Web-based survey of sedation practices from 165 expert endoscopists from 81 countries were analyzed. The most common sedation method was defined as that used for >50% of endoscopies within a country. RESULTS: Responses were received from 84 endoscopists practicing in 46 countries (51% response rate; 32 responses from 22 developing countries and 52 responses from 24 developed countries). A combination of benzodiazepine and opioid was the most common method for esophagogastroduodenoscopy (EGD) in 40% of the countries and for colonoscopy in 56% of the countries. For propofol and unsedated endoscopy, the corresponding figures were 8% and 19% for EGD and 18% and 10% for colonoscopy. No single sedation method accounted for >50% of EGD and colonoscopy cases in 32% and 17% of the countries, respectively. There were no significant differences in the proportions of developing and developed countries using combined benzodiazepine and opioid, propofol, or unsedated endoscopy. CONCLUSIONS: Sedation is used for most endoscopic procedures worldwide, with sedation practice not differing significantly between developing and developed countries.
Benzodiazepines ; Colonoscopy ; Developed Countries ; Developing Countries ; Endoscopy ; Endoscopy, Digestive System ; Europe ; Internet ; Propofol ; United States