1.New approaches for cholestasis in hemoglobinopathies.
Pratibha DHIMAN ; Priyanka SAXENA ; Chhagan BIHARI ; Archana RASTOGI ; S K SARIN
Blood Research 2015;50(2):118-121
No abstract available.
Cholestasis*
;
Hemoglobinopathies*
2.Cavernous sinus thrombosis following dental extraction: a rare case report and forgotten entity.
Karun AGGARWAL ; Sanjay RASTOGI ; Atul JOSHI ; Ashish KUMAR ; Archana CHAURASIA ; Rajat PRAKASH
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2017;43(5):351-355
Prior to the advent of efficacious antimicrobial agents, the mortality rate from cavernous sinus thrombosis (CST) was effectively 100%. There have been very few reports of CST associated with tooth extraction. A 40-year-old female presented to the emergency room with swelling over the right side of the face and history of extraction in the upper right region by an unregistered dental practitioner. The patient presented with diplopia, periorbital ecchymosis, and chemosis of the right eye. A computed tomography scan revealed venous dilatation of the right superior ophthalmic vein. The patient was immediately treated with incision and drainage, intravenous antibiotics, and heparin (low molecular weight). Unfortunately, the patient died two days after surgery due to complications from the disease. CST is a rare disease with a high mortality rate. Therefore, dental health education in rural areas, legal action against unregistered dental practitioners, early diagnosis, and aggressive antibiotic treatment can prevent future mortality resulting from CST.
Adult
;
Anti-Bacterial Agents
;
Anti-Infective Agents
;
Cavernous Sinus Thrombosis*
;
Cavernous Sinus*
;
Dilatation
;
Diplopia
;
Drainage
;
Early Diagnosis
;
Ecchymosis
;
Emergency Service, Hospital
;
Female
;
Health Education, Dental
;
Heparin
;
Humans
;
Mortality
;
Rare Diseases
;
Tooth Extraction
;
Veins
3.Cavernous sinus thrombosis following dental extraction: a rare case report and forgotten entity.
Karun AGGARWAL ; Sanjay RASTOGI ; Atul JOSHI ; Ashish KUMAR ; Archana CHAURASIA ; Rajat PRAKASH
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2017;43(5):351-355
Prior to the advent of efficacious antimicrobial agents, the mortality rate from cavernous sinus thrombosis (CST) was effectively 100%. There have been very few reports of CST associated with tooth extraction. A 40-year-old female presented to the emergency room with swelling over the right side of the face and history of extraction in the upper right region by an unregistered dental practitioner. The patient presented with diplopia, periorbital ecchymosis, and chemosis of the right eye. A computed tomography scan revealed venous dilatation of the right superior ophthalmic vein. The patient was immediately treated with incision and drainage, intravenous antibiotics, and heparin (low molecular weight). Unfortunately, the patient died two days after surgery due to complications from the disease. CST is a rare disease with a high mortality rate. Therefore, dental health education in rural areas, legal action against unregistered dental practitioners, early diagnosis, and aggressive antibiotic treatment can prevent future mortality resulting from CST.
Adult
;
Anti-Bacterial Agents
;
Anti-Infective Agents
;
Cavernous Sinus Thrombosis*
;
Cavernous Sinus*
;
Dilatation
;
Diplopia
;
Drainage
;
Early Diagnosis
;
Ecchymosis
;
Emergency Service, Hospital
;
Female
;
Health Education, Dental
;
Heparin
;
Humans
;
Mortality
;
Rare Diseases
;
Tooth Extraction
;
Veins
4.Post-liver transplant myeloid maturation arrest.
Anupama PATIL ; Chhagan BIHARI ; Neha NIGAM ; Deepika DEEPIKA ; Archana RASTOGI ; Viniyendra PAMECHA
Blood Research 2017;52(4):321-324
No abstract available.
Liver Transplantation
;
Liver Cirrhosis
;
Cytomegalovirus Infections
;
Cytomegalovirus
;
Cirrhosis, Cryptogenic
;
Graft Rejection
;
Bone Marrow
;
Time Factors
;
Humans
;
Male
;
Middle Aged
5.Tuberculosis of the Spleen as a Cause of Fever of Unknown Origin and Splenomegaly.
Biju POTTAKKAT ; Ashok KUMAR ; Archana RASTOGI ; Narendra KRISHNANI ; Vinay K KAPOOR ; Rajan SAXENA
Gut and Liver 2010;4(1):94-97
BACKGROUND/AIMS: Splenic involvement of tuberculosis, which is rare, warrants better definition in the current era of resurgence of tuberculosis. METHODS: Out of 339 splenectomies performed between January 1989 and December 2008 for indications other than trauma, histopathologic analysis of the spleen revealed tuberculosis in 8 patients. RESULTS: All eight patients were referred for splenectomy due to fever of unknown origin (FUO). No patient was infected with HIV, and all had at least moderate splenomegaly and hepatomegaly. Three patients had hypersplenism with bleeding manifestations. Radiologic evaluations demonstrated that splenic lesions were present in five patients. Five patients had evidence of tuberculosis manifested as enlarged splenic hilar lymph nodes, cystic lymph nodes, or liver. Two patients exhibited tubercle bacilli in their sputum during the postoperative period. CONCLUSIONS: In areas where tuberculosis is prevalent, tuberculosis should be considered in the differential diagnosis of patients presenting with FUO and splenomegaly. Extrasplenic involvement is usually seen in splenic tuberculosis, although it may not be apparent at presentation. Splenic tuberculosis can present in isolation without extrasplenic involvement, and even in immunocompetent individuals.
Diagnosis, Differential
;
Fever
;
Fever of Unknown Origin
;
Hemorrhage
;
Hepatomegaly
;
HIV
;
Humans
;
Hypersplenism
;
Liver
;
Lymph Nodes
;
Spleen
;
Splenectomy
;
Splenomegaly
;
Sputum
;
Tuberculosis
;
Tuberculosis, Splenic