Phytochemical constituents were isolated from the fruits of Acanthopanax chiisanensis by repeated column chromatography. Their structures were identified as beta-sitosterol (1), daucosterol (2), sesamin (3), chiisanogenin (4), and 22alpha-hydroxy chiisanogenin (5) by spectroscopic analysis (MS, 1H-, and 13C-NMR). Compounds 1 - 5 were isolated for the first time from the fruits of A. chiisanensis.
Eleutherococcus* ; Araliaceae ; Chromatography ; Fruit* ; Terpenes*

Study on preserved propagation of Polyscias fruticosa (L.) Harms – Araliaceae by direct regeneration from 3-years-old shoot tips. Shoot tips of 1.0 to 1.5cm long taken from field growing Polyscias fruticosa (L.) Harms were sterilized and cultured in Murashige and Skoog (MS) medium supplemented with 1.0mg/l BAP and 0.5mg/l IBA. After 8 weeks, these shoots began to regenerate directly from axil but quantity was not numerous and gave 2-3 new shoots after 4 more weeks. The results of rapid propagation of Polyscias fruticosa (L.) Harms’s shoots after 1, 3 and 4 months culture in MS + 2.0mg/l BAP + 0.5mg/l IBA environment showed that it was the best combination for shoot proliferation. The single shoots gained 2-3cm long were separated from shoot bushes and cultured in MS + 1.0mg/l IBA + 0.5mg/l BAP environment to make root the best. In this environment, shoots began to rooting after 11 days, gained 100% of rooting after 20 days. The plantlets were successfully transferred to PE bags. After 2 weeks, plantlets grew new roots with the rate of live 80-95%
Araliaceae ; Regeneration

The study was carried out to examine the proliferation in vitro of Polyscias fruticosa (L.) Harms. Results: Using HgCl 2 with concentration of 0.1% within 15 minutes and H2O2 within 30 minutes was the best of decontamination time. With the time, the live rate was >80%. Meristems of the branch of Polyscias fruticosa (L.) Harms were induced to develop into plantlets in a medium containing MS-minerals and 2.0 mg/l kinetin. In this medium, an average of 3.4+-0.62 shoots in about 60 days. 100% rooting of the shoots were induced in MS medium supplemented with 1.0 mg/l IBA in 30 days. Rooted planted were grown in the green house.
Araliaceae ; Greenhouse Effect

Both ethanol extracts of the bark and leaves of Schefflera elliptica (Blume) Harms (Araliaceae) showed antistress effect on mice at the oral doses of 158 and 167 mg/kg body weight, respectively. The bark proved to be more effective than the leaves, and their efficacity increased with the doses. Both extracts possessed in vitro antioxidant activity at the concentrations of 50-100 mcg/ml, the bark also being more effective than the leaves. The total saponin extract of the bark exhibited antioxidant effects at the levels of 5-25 mcg/ml. So, saponins might be the chemical constituents determining the antioxidant activity.
Plants ; Biochemistry ; Araliaceae ; Therapeutics

By NAMBA ‘weight method from leaf, root and stem of Schefflera sp. triterpen saponins were qualified. By thin layer chromatography, 11 stains of saponin were determined on leaf, 7 on stem and root with the quantities of 3,66%, 0,93%, 0,77% in absolutely dried leaf,stem and root, respectively. By thin layer chromatography 4 stains of total sapogenins of the leaf and 2 genins were isolated on column chromatography. Fusion points,chromatography,IR spectrum, 1H-NMR,13 C-NMR spectrography,DEPT,HMQC and HMBC had showed oleanolic and hederagenin in the structure of 2 genins
Saponins ; Araliaceae ; Sapogenins

Experimentally, hepatoprotective effect of DinhLang was expressed in mice. The extract of Dinh Lang leaf suppressed the increase of MDA level in brain and in liver of mice suffered from CCl4- induced hepatitis with antioxydant activity stronger than that of mixed extract and extract prepared from the root. Dinh Lang had manifested liver protective effect in tetrachlorurcarbone –induced acute hepatitis. Antioxydant effect expressed in the inhibition against the processes of peroxydation of cell membrane can be one of the mechanism of liver protective effect of Dinh Lang
Antioxidants ; Araliaceae ; liver

Extracts from roots and leaves of Polyscias fruticosa Harms. (Araliaceae) and their combination have been studied on lipid peroxidation in mouse brain using an auto-oxidation and a free radical generating system: the Fenton’s reagent (ferrous iron + hydrogen peroxide). All the root, leaf and combined extracts have inhibitory action on peroxidation of lipids and trolox, a water-soluble analogue of vitamin E used as a reference antioxidant compound. The results also indicate that the leaf extract is the strongest of all.
Biochemistry ; Plants ; Plants, Medicinal ; Araliaceae

Nineteen compounds, including one organic acid (1), one anthraquinone (2), one amide (3), and sixteen triterpenoid saponins (4 - 19) were isolated from the leaves of Acanthopanax henryi (Oliv.) Harms (Araliaceae). Their structures were determined on the basis of physicochemical properties and spectral analyses (HR-MS and NMR). Among them, compounds 2, 3, 7, 12 and 19 were new within Araliaceae. Compounds 4, 5, 9 - 11, 13, 14, 16 and 18 were reported for the first time from the Acanthopanax genus. Except for compounds 4 and 9, other compounds were isolated from A. henryi (Oliv.) Harms for the first time. The rare anthraquinone, compound 2, significantly decreased the production of NO and the levels of other inflammatory factors, such as TNF-alpha and IL-6, in lipopolysaccharide (LPS)-stimulated macrophages in a dose-dependent manner. This is the first time to report anti-inflammatory effect of this compound.
Eleutherococcus* ; Araliaceae ; Interleukin-6 ; Macrophages ; Nitric Oxide ; Saponins ; Tumor Necrosis Factor-alpha

Leaf spot and blight disease was observed on two-year-old seedlings of Dendropanax morbifera (Korean name: Hwangchil tree) during July of 2008 in Jindo Island, Korea. Symptoms included yellow-brown to dark brown irregularly enlarged spots frequently located along the veins of leaves. The lesions were often surrounded by chlorotic haloes. Severe leaf blight and subsequent defoliation occurred when conditions favored disease outbreak. The causal organism of the disease was identified as Alternaria panax based on morphological characteristics and sequence analysis of the internal transcribed spacer region of rDNA. A. panax isolates induced leaf spots and blight symptoms not only on D. morbifera but also on the other members of Araliaceae tested. This is the first report of foliar blight caused by A. panax on D. morbifera.
Alternaria ; Araliaceae ; Disease Outbreaks ; DNA, Ribosomal ; Korea ; Panax ; Seedlings ; Sequence Analysis ; Veins

This study was conducted to investigate the effects of Aralia elata, Acanthopanacis cortex and Ulmus davidiana water extracts on blood hemoglobin, HbA1c levels and biomarkers in the streptozotocin (STZ)-induced diabetic rats. Male Wistar rats divided into normal and diabetic groups. The diabetic groups subdivided into the control group (DM) and Araliaceae water extracts supplemented groups: Aralia elata (AE), Acanthopanacis cortex (AC) and Ulmus davidiana (UD). The extracts were supplemented in diet base on 11.42 g of raw Araliaceae/kg diet for 7 weeks. The diabetes was induced by injecting STZ (55 mg/kg B.W., i.p.) once 2 weeks before sacrifying. Relative weights of liver were significantly lowered in the DM group compared to the normal group, whereas those of kidney and heart were significantly increased in the DM group. Supplementation of the Araliaceae water extracts improved reduced liver weights in STZ-induced diabetic rats. Blood glucose level was significantly higher in the DM group than in the normal group, whereas insulin contents were significantly lowered in the DM groups. However, these parameters were normalized in the AE, AC and UD supplemented groups, respectively. Blood hemoglobin and HbA(1c) levels were significantly higher in the DM group than in the normal group. When all of Araliaceae water extracts were supplemented to the diabetic rats lowered hemoglobin and HbAI(1c) levels. Red blood cell, white blood cell and lymphocyte were significantly higher in the DM group than in the normal group. The supplementation of Araliaceae family water extracts significantly lowered these parameters compared to the DM group. MCV, MCH contents were declined in the DM group, while the supplementation of Aralia elata, Acanthopanacis cortex and Ulmus davidiana water extracts elevated of these contents in STZ-induced diabetic rats. Accordingly, these results indicate that Aralia elata, Acanthopanacis cortex and Ulmus davidiana water extracts would seem to improve the blood biomarkers in STZ-induced diabetic rats.
Animals ; Aralia ; Araliaceae* ; Biomarkers ; Blood Glucose* ; Diet ; Erythrocytes ; Heart ; Humans ; Insulin ; Kidney ; Leukocytes ; Liver ; Lymphocytes ; Male ; Rats* ; Rats, Wistar ; Streptozocin ; Ulmus ; Water* ; Weights and Measures