1.Assements the use of foot orthosis for children with cerebral palsy(CP)under direction by physician, technician and parents
Chinese Journal of Tissue Engineering Research 2001;5(9):31-
Objective To study assessments on the use of foot orthosis for children with CP under derection by physician, technician and parents. Method One hundred and ten children with CP using foot orthosis were divided into two groups. One group was intervened by the technicians of making foot orthosis, another group was intervened by the doctors, the technicians and patriarch trained, together. Result There was clear difference between the two group. The trial group was better than the control group (x2 = 30. 2, P < 0. 005) . Conclusion Assessments the use of foot orthosis for children with CP should be performed by the doctors, the technicians and patriarch trained together so that the curative effect of foot orthosis can be truly gained.
2.Balancing characteristics of children with spastic cerebral palsy during gait measurement using plantar pressure gait analysis system
Chinese Journal of Tissue Engineering Research 2009;13(17):3387-3391
OBJECTIVE: Usually, the balance tests of sitting and standing position are performed by balancing instruments clinicalty, but because of the restriction of foot pedal, this kind of instruments cannot measure balancing ability in continuous dynamic gait cycles in gait of cerebral palsy children. Using plantar pressure gait analysis system, this study sought to study balance characteristics in gait of children with spastic cerebral palsy.METHODS: A total of 78 healthy children served as normal control group, and 25 children with spastic cerebral palsy as cerebral palsy group at the Department of Rehabilitation, Shenzhen Children's Hospital from May 2004 to May 2007. A plantar pressure gait analysis system was used to perform plantar pressure gait analysis tests of children in both groups. All plantar pressure data of both groups was recorded. Main outcome measures contained quantized data including cadence, cycle time of gait, absolute symmetry index (ASI) of each gait phase, and visualized pressure diagram including dynamic plantar pressure diagram and center of Gravity's transfer track diagram.RESULTS: Comparing with normal control group, children of cerebral palsy group had fewer cadences and longer gait cycle time in gait (P<0.01). ASI of single-foot supporting phase, swing phase, double-foot supporting phase and gait cycle time of cerebral palsy group were higher than normal control group (P<0.05). Symmetry and repeatability of plantar pressure diagram of both feet were poorer than normal control group. Center of Gravity's transfer track diagram could not show as butterfly-shape graphics with good symmetry.CONCLUSION: ASI of each phase of gait cycle of spastic CP children increased significantly in gait. Plantar pressure gait analysis technology can be effectively applied to evaluate the balancing ability of children with spastic cerebral palsy in gait.
3.Effects of ankle-foot orthosis on gait characteristic in children with spastic cerebral palsy
Chinese Journal of Tissue Engineering Research 2010;14(17):3127-3130
BACKGROUND: Due to differences in designs and methods,the results of effects of ankle foot orthosis(AFO)on kinematics,kinetics and energy consumption during walking in children with cerebral palsy remain controversial.OBJECTIVE: To explore the effects of AFO on gait characteristics in children with spastic cerebral palsy.METHODS: A total of 21 ambulatory children with cerebral palsy were selected.A plantar pressure gait analysis system was used to perform plantar pressure gait analysis tests of participants when walking with an AFO and without an AFO at the same time of one day,under the same physical condition.All plantar pressure data were recorded,including cadence,cycle time of gait,absolute symmetry index(ASI)of each gait phase,and visualized pressure diagram including dynamic plantar pressure diagram and Center of Gravity's transfer track diagram.Visualized pressure diagrams were described and analyzed.RESULTS AND CONCLUSION: Gait cycle time was shortened in the children walking with an AFO compared with walking without an AFO(P< 0.01).ASI of single-foot supporting phase,swing phase,double-foot supporting phase and gait cycle time of children walking with AFO was significantly reduced compared with children walking without AFO(P < 0.05).Center of Gravity's transfer track diagram of children with cerebral palsy was disordered and could not show as butterfly-shape graphics with good symmetry.After wearing an AFO,the diagram became more ordered.Results show that when wearing an AFO,the gait cycle time in gait was shortened,and the cadence was increased; the symmetry of gait was improved,and the general walking ability was increased.Plantar pressure gait analysis technology can be effectively applied to evaluate the balancing ability of children with spastic cerebral palsy in gait using accurate data and visualized diagrams.
4.Investigation of Children with Cerebral Palsy in Rehabilitation and Their Families in Shenzhen
Qian GAN ; Anyan ZHOU ; Ying HU
Chinese Journal of Rehabilitation Theory and Practice 2011;17(3):277-279
ObjectiveTo investigate the children with cerebral palsy (CP) in rehabilitation, their families and need of society support. Methods150 children with CP in rehabilitation participated in this study. A questionnaire was designed to investigate their basic situation, family status, society concern and requirements for society support, which completed by their parents. Results150 questionnaires were completed efficiently. 75 children were firstly treated before 1 year old. The rehabilitation treatments were effective to 130 children. 126 children appeared some disorder in emotion and personality. Home education was the main rehabilitation way in 133 children. The educational background of 59.4% mothers were senior high school or below. The income was less than 60 thousand yuan in 76.7% families, but spent more than 40 thousand yuan per year on treatment in 54.7% families. One or both parents in 119 families were forced to stop working. 93.3% of them suffered emotion pressure and 56.7% lacked the knowledge about CP. 81% families thought that more social support should be offered in 6 aspects including government welfare, social security, medical institutions, psychotherapy, community services and legal aid. ConclusionAll society should pay more attention on the children with CP and provide a good rehabilitation environment for them.
5.Gait characteristics of children with spastic cerebral palsy assessed by dynamic plantar pressure measurement
Hai LI ; Anyan ZHOU ; Dongfeng HUANG ; Jianxin DING ; Qin JIANG
Chinese Journal of Tissue Engineering Research 2007;11(22):4457-4460
BACKGROUND:Pressure sensitive instrumented shoes are fast and easily used tools to measure ground reaction forces. Currently researches about the utilities of these systems in assessment of gait in children with neurological diseases have been started to run.OBJECTIVE: To find the gait characteristics of dynamic plantar pressure in children with spastic cerebral palsy. DESIGN: A cross-sectional study.SETTINGS: Department of Rehabilitation, Songgang People's Hospital; Department of Rehabilitation, Shenzhen Children's Hospital; Department of Rehabilitation Medicine, the First Affiliated Hospital of Sun Yat-sen University. PARTICIPANTS: ① Patient group: Twenty children with spastic cerebral palsy were selected from Shenzhen Children's Hospital from May 2004 to April 2005, including 9 boys and 11 girls, aged 26-66 months old, and they all could walk for more than 10 m independently. ② Normal control group: 52 healthy children with normal walking ability were enrolled, including 28 boys.and 24 girls, aged 35-76 months old.METHODS: Ultraflex gait analysis system was used to perform continuous plantar pressure tests of both groups of children. Diagram and data of dynamic plantar pressures in gait were recorded and analyzed with a computer. MAIN OUTCOME MEASURES: ① 10 sequential gait cycles were chosen from the continuous stable steps to calculate the average data with the software; ② Differences of the characteristic parameters of plantar pressure curve between the two groups.RESULTS: ① The curves of plantar pressure to time of testees in the normal control group were of the wave shapes with two peaks and one valley. Half of the CP children could not perform the two-peak shape pressure curve in the gait analysis. One kind of abnormal plantar pressure curve style was a wave shape with only one peak. Another kind of abnormal plantar pressure curve style was a shape showing asymmetry between sides and variation in different steps even in the same side. Two-peak shapes of dynamic plantar pressure were recorded in 10 CP children. ② Characteristic parameters picked up from the curves of plantar pressure had been compared between the two groups. Significant difference have been found in ts of both sides and tz1,tz2,tz3 on the right side between the two groups. It was shown that the single-limb support time of both sides in the CP children was longer than that in healthy children [left: (0.879± 0.658), (0.472±0.051) s; right: (0.818±0.682), (0.478±0.050) s; P < 0.01]. The tz1 and tz3 on the right side in the CP children were longer and while the tz2 was shorter than those in the healthy children. CONCLUSION: ① Using dynamic plantar pressure gait analysis system, plantar pressure curves can be observed directly, and information about kinetic characters can be drawn straightly. ② Part of patients with spastic CP could not perform the two-peak shape pressure curves in gait analysis. In patient can be recorded of two-peak shape dynamic plantar pressure curves, ts of both sides are shorter than those in healthy children, tz1 and tz3 on the right side is longer and tz2 is shorter than those in healthy children.
6.Analysis of the Results of ELISA by Detecting Low Quantitative HBsAg(CMIA)in Serums
Anyan DENG ; Yanjuan CAI ; Shourong ZHOU ; Qiang WANG ; Dongsheng WANG ; Guoyuan ZHANG ; Quming FAN ; Xiaolan GUO
Journal of Modern Laboratory Medicine 2015;(2):123-125
Objective To evaluate the performance of ELISA by detecting low quantitative HBsAg in serums.Methods 305 serum samples that the quantitation range was from 0.05 IU/ml to 9.99 IU/ml were collected,and then detected by ELISA. Results The rate of patients with low quantitation of HBsAg was 18.12% in patients with positive HBsAg.The total de-tected rate of ELISA was 87.87%,and the rate of 0.05~0.11,0.12~0.20,0.21 ~0.50,0.51 ~ 1.00,1.01~5.00 IU/ml and 5.01~9.99IU/ml were 36.00%,61.11%,78.38%,84.62%,99.11% and 100.00%,respectively.The differences were statistically significant between the detected rates of each group(χ2 =99.84,P =0.000).There was high correlation coeffi-cient between the results detected by ELISA and by CMIA(r = 0.874,P = 0.000).Conclusion The clinical laboratory should be careful to apply the method of ELISA to detect HBsAg for its missing detection in samples with low quantitation of HBsAg.