1.Geriatic Anxiety Disorder.
Journal of Korean Geriatric Psychiatry 2006;10(2):61-64
Anxiety disorder is the one of the most prevalent psychiatric disorders in the elderly. However, there were no sufficient studies on the anxiety disorder in late life. Geriatric anxiety disorders are under-diagnosed and under-treated. For the proper evaluation and diagnosis of anxiety disorder in the elderly, comprehensive approaches considering medical, psycho-social aspects are needed. Various treatment modalities including pharmacotherapy and psycho-social treatments were reported. In this article, the author reviewed the general features of geriatric anxiety disorders, epidemiological characteristics, clinical features of each anxiety disorders, and treatment issues. We need more systematized studies for the advances on the diagnosis and treatment of geriatric anxiety disorders.
Aged
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Anxiety Disorders*
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Anxiety*
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Diagnosis
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Drug Therapy
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Humans
2.Effects of staged acupuncture on endometrial receptivity and anxiety in patients with recurrent implantation failure of thin endometrium based on "thoroughfare vessel is the sea of blood" theory.
Li-Wei XING ; Zhe HE ; Yu-Huan SUN ; Ming HE ; Shun YU ; Yang CHEN ; Jin-Long XU ; Rui MEI ; Rong ZHAO
Chinese Acupuncture & Moxibustion 2023;43(3):289-293
OBJECTIVE:
To compare the clinical efficacy between staged acupuncture based on "thoroughfare vessel is the sea of blood" theory combined with routine hormone replacement cycle treatment and routine hormone replacement cycle treatment for patients with recurrent implantation failure (RIF) of thin endometrium.
METHODS:
A total of 72 RIF patients with thin endometrium were randomly divided into an observation group and a control group, 36 cases in each group. The patients in the control group were treated with routine hormone replacement cycle treatment. Based on the treatment of the control group, the patients in the observation group were treated with staged acupuncture based on "thoroughfare vessel is the sea of blood" theory. The main acupoints were Neiguan (PC 6) and Gongsun (SP 4), and the supplementary acupoints were selected according to the menstrual cycle and syndrome differentiation; the acupuncture was given once every other day, 3 times a week, for 3 consecutive menstrual cycles. The thickness and shape of endometrium, and Hamilton anxiety scale (HAMA) score were observed at implantation window before and after treatment; the clinical pregnancy rate, live birth rate and cycle cancellation rate were compared between the two groups; the correlation between endometrial thickness and HAMA score was analyzed.
RESULTS:
Compared before treatment, the endometrial thickness in the two groups and the proportion of type A+B endometrium in the observation group were increased (P<0.05), and the HAMA scores in the two groups were decreased (P<0.05) after treatment. The above indexes in the observation group were superior to those in the control group (P<0.05). The clinical pregnancy rate and live birth rate in the observation group were higher than those in the control group (P<0.05), and the cycle cancellation rate was lower than that in the control group (P<0.05). There was a negative correlation between endometrial thickness and HAMA score (P<0.05).
CONCLUSION
Based on the routine hormone replacement cycle treatment, the addition use of staged acupuncture based on "thoroughfare vessel is the sea of blood" theory could improve the thickness and shape of endometrium, relieve anxiety, increase the clinical pregnancy rate and live birth rate, and reduce the cycle cancellation rate in RIF patients with thin endometrium. The curative effect is superior to the routine hormone replacement cycle treatment alone.
Female
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Pregnancy
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Humans
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Anxiety
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Anxiety Disorders
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Acupuncture Therapy
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Endometrium
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Hormones
3.Acupuncture and moxibustion treatment of anxiety neurosis and study on characteristics of acupoint selection.
Chinese Acupuncture & Moxibustion 2008;28(7):545-548
Review and summarize the published literature since 1994 on treatment of anxiety neurosis with acupuncture and moxibustion, so as to provide evidence for standard acupuncture and moxibustion treatment program. It is indicated that Baihui (GV 20), Neiguan (PC 6), Shenmen (HT 7), Sanyinjiao (SP 6), Yintang (EX-HN 3), etc. were the most commonly selected for clinical treatment of anxiety neurosis. Acupuncture and moxibustion treatment of anxiety neurosis stresses the special function of acupoints in acupoint selection, reflecting the therapeutic characteristics of "treatment based on the brain" and "treatment based on the heart" for mental disorders, and emphasizing the important position of TCM Zang- and Fu-organs syndrome differentiation in treatment of anxiety neurosis.
Acupuncture Points
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Acupuncture Therapy
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methods
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Anxiety Disorders
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therapy
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Humans
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Moxibustion
4.Effects of acupoint specificity on claustrophobia.
Zhihao LI ; Wei ZOU ; Xueping YU
Chinese Acupuncture & Moxibustion 2018;38(9):948-952
OBJECTIVE:
To observe the effectiveness of acupuncture on claustrophobia, and to explore the effects of acupoint specificity on claustrophobia.
METHODS:
This was an evaluator-blinded randomized controlled trial. One hundred and sixty patients who presented with claustrophobia during magnetic resonance imaging examination were randomized into an acupoint group, a non-acupoint group, a sham-acupoint group and a blank group, 40 cases in each one. The patients in the acupoint group were treated with acupuncture at Zhaohai (KI 6), Taichong (LR 3), Lingdao (HT 4), Neiguan (PC 6), Shenmen (HT 7), Danzhong (CV 17), Baihui (GV 20) and Fengchi (GB 20). The patients in the non-acupoint group were treated with acupuncture at points 0.5 next to the acupoints above. The patients in the sham-acupoint group were treated with acupuncture at acupoints not closely correlated to claustrophobia in corresponding segment. All the acupuncture was given once. No treatment was used in the blank group. The state anxiety questionnaire (S-AI) was observed in all the patients at the end of MRI examination before and after treatment. The clinical therapeutic effects were compared among four groups.
RESULTS:
Compared before treatment, the S-AI score was reduced in the acupoint group, non-acupoint group and sham-acupoint group after treatment (<0.05, <0.01); the differences of S-AI score before and after treatment in the blank group were not statistically significant (>0.05). After treatment, the S-AI scores in the acupoint group, non-acupoint group and sham-acupoint group was lower than that in the blank group (<0.05, <0.01), and the differences of S-AI score were higher than that in the blank group (<0.01). The S-AI score in the acupoint group was lower than that in the non-acupoint group and sham-acupoint group (<0.05), and the difference of S-AI score was higher than those in the non-acupoint group and sham-acupoint group (<0.05). The difference of S-AI score in the non-acupoint group was higher than that in sham-acupoint group (<0.05). The total effective rate was 92.5% (37/40) in the acupoint group, which was significantly superior to 25.0% (10/40) in the non- acupoint group, 17.5% (7/40) in the sham-acupoint group and 5.0% (2/40) in the blank group (<0.05, <0.01).
CONCLUSION
Acupuncture showes superior effect on claustrophobia, and its tranquilizing effect may be related with acupoint specificity.
Acupuncture Points
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Anxiety
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Humans
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Phobic Disorders
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therapy
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Surveys and Questionnaires
5.1-Year Follow-Up of Mindfulness-Based Cognitive Therapy in Patients with Generalized Anxiety Disorder or Panic Disorder.
Ji Won YUN ; Sang Hyuk LEE ; Yong Woo KIM ; Myo Jung KIM ; Keunyoung YOOK ; Mi RYU ; Tae Kyou CHOI ; Keun Hyang KIM
Journal of Korean Neuropsychiatric Association 2009;48(1):36-41
OBJECTIVES: Mindfulness-base cognitive therapy (MBCT) has been used to treat patients with depression to prevent relapse. The purpose of this study was to examine the effectiveness of Mindfulness- Base Cognitive Therapy for patients who suffer with generalized anxiety disorder or panic disorder for 1 year. METHODS: 19 patients with generalized anxiety disorder or panic disorder were assigned to receive MBCT for a period of 8 weeks. The Hamilton Anxiety Rating Scale (HAM-A), the Hamilton Depression Rating Scale (HAM-D), the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI) were used at 0 weeks, 8 weeks and 1 year to assess the results. RESULTS: MBCT demonstrated significantly decreases on all the anxiety scale scores (HAM-A, p=0.00 ; BAI, p=0.00) and depressive scale scores (HAM-D, p=0.00 ; BDI, p=0.00). The patients who received 8-week of MBCT showed a higher remission rate (15/19, 78%) during the 1-year followup period. CONCLUSION: MBCT may be effective at relieving the anxiety and depressive symptoms of patients who suffer with generalized anxiety disorder or panic disorder for 1 year. However, further well-designed controlled trials are needed to assess the value of MBCT.
Anxiety
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Anxiety Disorders
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Cognitive Therapy
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Depression
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Follow-Up Studies
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Humans
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Panic
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Panic Disorder
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Recurrence
6.Pharmacotherapy Strategies in Anxious Elderly Patients.
Journal of Korean Geriatric Psychiatry 2003;7(1):34-41
To provide a recent knowledge about pharmacological treatment of anxiety disorders in elderly, the author reviewed the articles and books for the treatment of elderly anxiety patients. Anxiety is the one of the most prevalent psychiatric symptoms in the elderly. Many psychological and physical causes including used drugs can induce the anxiety symptoms in elderly. However, it is often unrecognized and inadequately treated. The pharcokinetics and pharmacodynamic changes, con-comittent illnesses, compliance problems, and increased sensitivity to drugs in elderly have to be considered. Various pharmacological treatments (e.g benzodiazepines, buspirone, antidepressnats, beta-blockers, antihistamines, neuroleptics)were reported as having therapeutic effects for the treatment of geriatric anxiety disorders patients. They have their own advantages and disadvantages. However, anxiety in elderly have received little focus to date. The study results often depend on the studies from adult samples. A comprehensive, flexible, integrated, and specific treatment approaches should be applied to elderly anxious patients. The more systematized studies are needed to broaden the knowledge of the pharmacological treatment of anxiety disorders in the elderly.
Adult
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Aged*
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Anxiety
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Anxiety Disorders
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Benzodiazepines
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Buspirone
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Compliance
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Drug Therapy*
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Histamine Antagonists
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Humans
7.Neuro-stimulation Techniques for the Management of Anxiety Disorders: An Update.
Sujita Kumar KAR ; Siddharth SARKAR
Clinical Psychopharmacology and Neuroscience 2016;14(4):330-337
Neuro-stimulation techniques have gradually evolved over the decades and have emerged potential therapeutic modalities for the treatment of psychiatric disorders, especially treatment refractory cases. The neuro-stimulation techniques involves modalities like electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS) and others. This review discusses the role of neuro-stimulation techniques in the treatment of anxiety disorders. The various modalities of neuro-stimulation techniques are briefly discussed. The evidence base relating to use of these techniques in the treatment of anxiety disorders is discussed further. The review then highlights the challenges in conducting research in relation to the use of neuro-stimulation techniques with reference to patients with anxiety disorders. The review provides the future directions of research and aimed at expanding the evidence base of treatment of anxiety disorders and providing neuro-stimulation techniques as promising effective and acceptable alternative in select cases.
Anxiety Disorders*
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Anxiety*
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Electroconvulsive Therapy
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Humans
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Transcranial Direct Current Stimulation
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Transcranial Magnetic Stimulation
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Vagus Nerve Stimulation
8.Pharmacotherapy of Anxiety Disorders in Older People.
Journal of Korean Geriatric Psychiatry 2006;10(2):70-75
Anxiety disorders are common psychiatric illnesses in the elderly. However, anxiety disorders in older people have not drawn much attention from researchers and clinicians alike, compared with late-life depression or dementia. The author searched for articles published from 1986 to 2006 using the key words including "anxiety", "elderly", "aged", and "pharmacological" therapy in the MEDLINE, PsychINFO, and KMbase in order to clarify effective pharmacological therapy in the elderly with anxiety disorders. Well designed studies for pharmacologic intervention in late-life anxiety disorders were rarely found. Nonetheless, studies on young adults demonstrated a number of pharmacological treatment options that can be applied to these patients. Pharmacologic treatments for the elderly include therapies using antideprssants, especially SSRI or SNRI, buspirone, or benzodiazepines. The latter requires special caution in the administration in the elderly because it can lead to adverse events. Therefore, well designed clinical trials are further needed to obtain optimal pharmacological intervention for the elderly with anxiety disorders.
Aged
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Anxiety Disorders*
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Anxiety*
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Benzodiazepines
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Buspirone
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Dementia
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Depression
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Drug Therapy*
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Humans
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Young Adult
9.Anxiety Sensitivity and Quality of Life in Patients with Acne
Ersoy ACER ; Ali Ercan ALTINOZ ; Hilal Kaya ERDOGAN ; Esra AGAOGLU ; Nihan YUKSEL CANAKCI ; Zeynep Nurhan SARACOGLU
Annals of Dermatology 2019;31(4):372-377
BACKGROUND: Anxiety sensitivity (AS) is a continuous fundamental fear and defined as extreme fear of anxiety sensations and symptoms. High AS can cause tendency to anxiety disorders. There are many studies evaluating the anxiety in patients with acne; however, AS has not been investigated. OBJECTIVE: We aimed to investigate AS in patients with acne. METHODS: Two hundred and fourteen acne patients and 117 healthy control subjects, aged older than 16 years were enrolled in the study. Severity of acne was evaluated by Global Acne Grading System. The acne patients and healthy controls were asked to complete the anxiety sensitivity index-3 (ASI-3), the Beck anxiety inventory (BAI) and the Turkish version of acne quality of life index. RESULTS: Anxiety and AS levels in acne patients were significantly higher than healthy controls (p<0.001). Quality of life was impaired in acne patients. Quality of life was negatively correlated with anxiety and AS levels in acne patients (p=0.014, p=0.019, respectively). There was no correlation between quality of life and disease severity (p=0.556) and also there was no correlation between psychiatric scale scores (ASI-3, BAI) and disease severity (p=0.147, p=0.871, respectively). CONCLUSION: To our knowledge, our study is the first to report that AS is high in acne patients. Clinically, our results suggest that there might be a relationship between AS and acne. We conclude that further studies are needed in order to clarify the relationship between acne and AS and to investigate the efficacy of cognitive behavioral treatments in acne patients.
Acne Vulgaris
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Anxiety Disorders
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Anxiety
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Cognitive Therapy
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Humans
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Quality of Life
;
Sensation
10.Progress on the researches of acupuncture preconditioning before surgery.
Meng-Yue GU ; Huo-Lin ZENG ; Feng-Cheng DENG ; Yong-Jun ZHANG ; Hui ZHONG
Chinese Acupuncture & Moxibustion 2023;43(6):727-732
This paper reviews the researches on acupuncture preconditioning before surgery in recent years and explores its application value from three aspects, i.e. relieving preoperative anxiety, preventing from postoperative cognitive dysfunction, and preventing from postoperative gastrointestinal dysfunction. As a relatively safe non-drug treatment, acupuncture has the underlying advantages in participating into multidisciplinary coordination in the enhanced recovery after surgery (ERAS). By building up higher-quality medical evidences and revealing the effect mechanism of acupuncture from multi-dimenisonal aspects, it is expected that acupuncture technology can be coordinated with ERAS to optimize the clinical path in the perioperative period, and boost the development of the perioperative medicine ultimately.
Humans
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Acupuncture Therapy
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Anxiety
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Anxiety Disorders
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Enhanced Recovery After Surgery
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Perioperative Period