1.Detection of echinococcosisinfections in Mongolia using ELISA with recombinant AgB and Em18 antigens.
Anu D ; Abmed D ; Sako Y ; Ito S ; Ito A
Mongolian Medical Sciences 2012;160(2):12-17
Background. Echinococcosis are parasitic zoonoses, remains a public health problem of worldwide, including Mongolia . Differential diagnosis between E.granulosus and E.multilocularis has significant implications for epidemiologic studies, treatment of these diseases, since both species occur in Mongolia. Serodiagnostic tests based on detection of antibodies against genus and species-specific antigens have played an important role in differential diagnosis, confirming clinical diagnosis and in epidemiologic studies.Materials and Methods. A total of 107 volunteer participants’ serum samples and additional 11 serum samples from the persons with hepatic cysts were tested for specific IgG against recombinant AgB and recombinant Em18 antigens in an ELISA .Results.rAgB-specific antibody was detected in 2 (3.33) of 60 individuals from Bayankhongor province and no one had positive response to this antigen in 46 individuals from Ulaanbaatar city while rEm18-specific antibody was present in 7 (11.66) and 3 (6.38) respectively. The one individual with typical lesions of active echinococcosis in a liver revealed by abdominal ultrasonography showed significantly higher IgG antibody response to rAgB. We suggest that people need to be provided information not only about cystic echinococcosis but also alveolar echinococcosisand improvement of sanitation and hygiene and to be careful with corsac and red foxes and their feces to prevent those infections.
2.Detection of bacterial meningitis among children in Ulaanbaatar, Mongolia from 2002 to 2010
AItantsetseg D ; Sarantuya J ; Bulgan D ; Baatarkhuu O ; Carvalho Mda G ; Anu D ; Sodbayar D
Mongolian Medical Sciences 2011;158(4):48-55
Background. Bacterial meningitis is a severe, potentially life-threatening infection that is associated with high rates of morbidity and significant disability in survivors. Overall mortality rates related to bacterial meningitis of around 20% to 25% have been reported by major centers. Our study is to determine the incidence rate and etiology of childhood bacterial meningitis in Ulaanbaatar, Mongolia.Methods. From 2002-2010, a total of CSF 433 and blood 544 samples were obtained from children age 0-5 years old. The following diagnostic criteria for bacterial meningitis in children aged 0-5 years were used: questionnaires, clinical signs and positive CSF culture and/or CSF antigen test results positive N. meningitis serogroups B, A, C, Y, and W-135, Hib or S.pneumonia; and/or positive CSF PCR results; and/or positive blood culture results with CSF pleocytosis (WBC count, >10 cells/uL). Pathogens were identified and serotype or serogroup with standard methods in the reference microbiology laboratory. Detection of bacterial pathogens with a multiplex and real-time PCR assay.Results. From totally 544 suspected cases had been detected bacterial meningitis in 260 (47, 8%) cases and sepsis in 111 [20,4%] cases respectively. The disease in the 83 [27.1 %] etiologically diagnosed patients was due to H.influenza, S. pneumonia was in 71 [36, 4%] cases and N.meningitis in 111 [24, 7%] respectively. Among the positive samples 80.6% (129/160) the specific serogroup and/or serotypes for N.meningitis serogroups A was available in 22(35, 4%) cases, for the Hib 52(96, 3%) and 6(40%) for the S.pneumoniae 7 serotype. The real time PCR assay was more sensitive for detection of meningitis pathogens than conventional methods (culture and latex agglutination), 19% in comparison with latex agglutination (p<0.0026) and by 39% in comparison with culture (p<0.001). Bacterial meningitis was identified 70.0 in 2004 among population, but it reduced until 5.0 in 2009. The incidence of Hib meningitis was 2002-2005y, N.meningitis and S.pneumoniae meningitis were 2006-2008y, S.pneumonia meningitis was more higher 2009-201 Oy comparing with other pathogens.Conclusion. N.meningitidls, S.pneumoniae H.influenzae type b are the leading causative agents of childhood bacterial meningitis in Ulaanbaatar, and the incidence rate is higher than what were reported in other Asian countries.
3.Health risks of overweight and obesity among children
Otgonjargal D ; Bayasgalan J ; Anu P
Mongolian Medical Sciences 2023;203(1):53-58
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Childhood obesity is, according to the WHO, one of the most serious challenges of the 21st century. More than 100 million children have obesity today. Globally, the prevalence of obesity and overweight tripled in the child and youth populations from the mid-1970s (about 4%) to 2016 (greater than 18%). In 2016, more than 330 million children and adolescents were affected by overweight or obesity globally. It is estimated that by 2030 nearly 30% of all children will be affected by overweight or obesity. For this reason, childhood obesity is a major public health problem worldwide.
This study summarizes and reviewed research findings related to childhood obesity and health risks. Overweight and obesity are defined as an abnormal or excessive accumulation of fat that can harm health. Obesity has a multifactorial origin that involves both genetic and environmental factors. Several studies showed that excess body fat increased the risk of multiple comorbidities, such as high blood pressure, coronary heart disease, type 2 diabetes, insulin resistance, and cancer. According to the results of the research, the mother's nutritional status and obesogenic environments have a great influence on childhood obesity. A summary of the results of many studies concluded that childhood obesity is more likely to develop non-communicable diseases in adulthood. The global prevalence of overweight in children aged 5 years or under has increased modestly, but with heterogeneous trends in low and middle-income regions, while the prevalence of obesity in children aged 2–4 years has increased moderately. Overweight or obesity during childhood has important short-term and long-term consequences.
Conclusion
In recent decades, the prevalence of obesity in children has increased dramatically. For the successful implementation of activities to prevent overweight and obesity in children, it is necessary to create a supportive environment and to promote health.
4.Determination of concentrations of indoor air pollutants emitted from briquette combustion
Oyun-Erdene O ; Chinzorig B ; Barkhasragchaa B ; Tumendelger D ; Solongo Ch ; Anu B ; Burmaajav B ; Suvd B
Mongolian Medical Sciences 2022;199(1):53-61
Introduction:
This field assessment was performed to ensure the effective implementation of Order No. A/142 of the Deputy Prime Minister of Mongolia dated 30th December 2021 and Order No. A/01 of the Head of the National Committee for Reducing Environmental Pollution dated 3rd January 2022 and to monitor the level of indoor air pollutants emitted from traditional stoves and standard stoves.
Purpose:
To determine the level of indoor air pollutants emitted from briquette combustion and to develop recommendations by comparing various types of stoves and dwellings.
Materials and Methods:
Through analytical cross-sectional designs, three households from Songinokhairkhan district and one household from Chingeltei district were selected to participate in this assessment as they use briquettes for heating, vary in their dwelling types (ger (traditional Mongolian tent), house) and their stove types (traditional, standard), stay home during the day and chose to participate in the assessment. 24-hour continuous measurements were conducted for each dwelling and before taking measurements, we calibrated and adjusted the air suction velocity of the measuring instrument at the Central Metrology Laboratory. The monitor was placed at a distance of 0.5m from the stove and a height of 0.5-1.0m from the floor. The results were then compared with the Mongolian National Standard “General air quality and technical requirements MNS4585:2016” and WHO Guidelines for Indoor Air Quality 2021. Statistical analysis was performed using SPSS 24.0 software, mean, ANOVA test, and if the p-value is less than 0.05, our results are statistically significant.
Results:
The concentration level of SO2 in houses with “Dul” stoves was within the level specified in the Mongolian standard MNS4585: 2016 and WHO Guidelines for Indoor Air Quality 2021, while 24-hour SO2 concentration in gers and houses with traditional stoves was 1.3-2.92 times higher than the standards. The 24-hour average concentration of nitrogen dioxide in houses with traditional stoves was 1.73 times higher than the Mongolian air quality standard MNS4585: 2016. There were statistically significant differences in the emission levels of SO2 and NO2 depending on dwelling and stove types (df=4, f=4.04, p=0.008 and df=4, f=17.17, p=0.001, respectively.). The 8-hour average (10,000 μg/m3) CO concentration was statistically significant for various types of dwellings and stoves (df=4, f=45.17, p=0.001), whereas there was a statistically significant difference in CO concentrations in gers with traditional stoves and gers with standard stoves in terms of morning, afternoon, and evening hours (df=3, f=33.17, p=0.001).
Conclusion
Indoor air pollutants in the households except for houses with “Dul” stoves have been determined to exceed the air quality standards set by the Mongolian air quality standards and WHO Guidelines for Indoor Air Quality 2021.