ASLO is an antibody to streptolysin O. Streptolysin O is a hemolysin that produced by group A beta-hemolytic Streptococcus. Streptococcus can cause upper respiratory tract infection, acute glomerulonephritis and rheumatic fever. The rate of ASLO occurrence is 35.22%, in which 12.61% have pathological value with average titer of ASLO is 172.41 Todd. The children under 10 years old have ASLO occurrence rate higher than children over 10 years old. There was not difference between males and females. The rate of group A beta-type Streptococcus isolation is 21.30%.
Antistreptolysin O ; child

No abstract available.
Antistreptolysin* ; Child* ; Humans ; Reference Values* ; Seoul*

PURPOSE: To know the true carrier rate and the immunologic responses (antistreptolysin O :ASO) to beta-hemolytic streptococci which obtained from normal school children with or without carrying streptococci. And to study the clinical meaning of the number of organisms found in culture. METHODS: One hundred ninty-eight first grade of elementary school children were included. I obtained throat swab culture from tonsil and tonsilar fossa with sterile cotton ball stick and plated on sheep blood agar dish, counted number of colonies of beta-hemolytic streptococci (BHS) after overnight incubation, examined ASO titer (Rantz-Randall method) simultaneously, and differentiated grouping of BHS with Streptex. RESULTS: 1) Of the 198 normal school children, 34 (17.2%) had cultured BHS. 16 (8.1%) were group A, 4 (2.0%) were group C, 2 (1.0%) were group G, and 12 (6.1%) were non-grouping BHS. 2) 14 (22.2%) out of 63 normal children without carrying BHS and 16 (47.1%) out of 34 with carrying BHS had come out above 250 units of ASO. 13 (59.1%) out of 22 group A,C,G streptococcal carriers had showed above 250 units of ASO. The true carrier rate of BHS were 18 (9.0%) out of 198 elementary school children. 3) When I had counted the number of colonies from 34 carrier of BHS, 1+ was 67.6% and 2+ was 17.6%. It was 85.2% of total children with carrier. 4) There were significant differences between the mean titer of logarithmic ASO obtained from group A BHS carrier and that of normal children without carrying BHS (P=0.001), and differences between that of group A and group B,C,G streptococci (P= 0.0005). CONCLUSIONS: The ASO titer obtained from BHS carrier is higher than normal school children, which suggests the possibility of subclinical infection, the possibility of persistent habor of organism since past infection had contracted, and the possibility of replaced old organism in past infection with new organism. It should be performed follow-up study for identifying the persistence of immunologic response in accordance with or without culturing organism.
Agar ; Antistreptolysin* ; Asymptomatic Infections ; Child* ; Humans ; Palatine Tonsil ; Pharynx* ; Sheep

PURPOSE: Measurement of antistreptolysin O (ASO) is often necessary to confirm a clinical diagnosis of recent streptococcal infection, especially in patients suspected of rheumatic fever and acute glomerulonephritis. Standard normal ranges for ASO should be established locally for each age group. We analyzed ASO to determine the upper limit of normal (ULN) ASO in children in the Gyeonggi-Incheon area. METHODS: ASO in normal individual concentrations were measured quantitatively by nephelometry on sera from 753 children (Male:381, Female:372). ULN were determined by separating the upper 20% from the lower 80% of the group (80 percentile). RESULTS: The mean ASO concentration calculated in a total cases was 149.9+/-7.2 IU/mL. The ASO concentration in neonates was 83.4+/-10.7 IU/mL, and lowest in the 1 year of age group, 26.7+/-6.6 IU/ mL, and increased to 318.0+/-33.2 IU/mL gradually in the 9 years of age group. Thereafter, ASO concentration decreased. The ULN for neonates was 122 IU/mL, for 0-3 years, 40 IU/mL; for 4-6 years, 113 IU/ mL; for 7-9 years, 489 IU/mL; for 10-19 years, 433 IU/mL; for 20-29 years, 122 IU/mL. CONCLUSION: The age-specific ULN for children in the Gyeonggi-Incheon area were determined. The distribution of ASO concentration according to age groups was different from previous reports. These results should be of clinical value to physicians to interprete the ASO results of their patients.
Antistreptolysin* ; Child* ; Diagnosis ; Glomerulonephritis ; Humans ; Infant, Newborn ; Nephelometry and Turbidimetry ; Pediatrics ; Reference Values ; Rheumatic Fever ; Streptococcal Infections

Although throat culture is a gold standard to diagnose group A streptococcal (GAS) pharyngitis or its sequelae, antistreptolysin O (ASO) is useful to confirm the diagnosis. In case there is no elevation of ASO, it is necessary to add one or more serologic tests, such as antideoxyribonuclease (ADNase) B test. ADNase B levels were analyzed in the carriers of beta-hemolytic streptococci (BHS) in this study. ADNase B concentrations were determined quantitatively by nephelometry (Behring Nephelometer 100 Analyzer, Germany) on 157 sera of healthy elementary school children in Chungnam who were positive of BHS in the throat culture. ASO levels were measured previously by autoanalyzer (Hitachi 747, Japan). Mean ADNase B and ASO levels were compared according to serological group of BHS and number of colonies. The carriers of GAS had significantly higher ADNase B levels (mean 453 IU/ml) than those of non-A beta-hemolytic streptococci (NGAS, 278 IU/ml), while the difference of ASO levels between GAS (482 IU/ml) and NGAS (350 IU/ml) carriers was not so high. The carriers who had more than 10 CFU of BHS had significantly higher ADNase B or ASO levels than those who had less than 10 CFU. The correlation between ADNase B (Y) and ASO (X) was Y=0.4X+229 (r2=0.13). ADNase B test could discriminate GAS from NGAS more effectively than ASO test. The carriers who have more than 10 CFU might undergo asymptomatic infection, as their ADNase B or ASO levels were significantly high. Because distribution of ADNase B showed little correlation to that of ASO, ADNase B test could be used as a supplementary test to diagnose GAS infection.
Antistreptolysin ; Asymptomatic Infections ; Child ; Chungcheongnam-do ; Diagnosis ; Humans ; Nephelometry and Turbidimetry ; Pharyngitis ; Pharynx ; Serologic Tests

BACKGROUND: Antistreptolysin O (ASO) is very useful as an indicator of recent streptococcal infection and its sequelae, such as rheumatic fever and acute glomerulonephritis. Because the upper limit of normal (ULN) value of ASO varies according to age, the ULN value of ASO in an area should be evaluated to accurately interpret single ASO levels of patients. METHODS: The ULN value and distribution of ASO concentrations were investigated in three age groups of preschool children (N=162), elementary school children (N=436), and adults (N=231) in Chinju. ASO concentra-tions were measured quantitatively by autoanalyzer or nephelometer from sera of healthy population in Chinju who had no symptoms or signs of streptococcal infec-tions. RESULTS: The mean(+/-SD) ASO concentrations were 71(+/-107) IU/mL, 285(+/-246) IU/mL, and 80(+/-64) IU/mL and the UNL value of ASO concentrations were 131 IU/mL, 433 IU/mL, and 136 IU/mL in each group of preschool children, elementary school children, and adults, respectively. CONCLUSION: The distribution and ULN value of ASO concentrations varied according to age group. The ULN value of ASO concentrations should be set differ-ently according to the patient' s age. Group A strepto-coccal infections might be quite common in elementary school children, while very rare in preschool children or adults.
Adult ; Antistreptolysin* ; Child ; Child, Preschool ; Glomerulonephritis ; Gyeongsangnam-do ; Humans ; Rheumatic Fever ; Streptococcal Infections

BACKGROUND: Antistreptolysin O (ASO) has been widely used to diagnose Streptococcus Pyogenes infections and their sequelae, rheumatic fever and acute glomerulonephritis. Butt in some cases there is no elevation of ASO that it is necessary to add one or more tests detecting immune response to S. pyogenes.. The authors analyzed the distribution of antideoxyibonuclease (ADNase) B and antistreptolysin O (ASO) among the children of an elementary school in Seoul and calculated their upper limit of normal (ULN) value. METHODS: ADNase B concentrations were determined by nephelometry (Behring Nephelometer 100 Analyzer, Germany) on 236 sera of healthy elementary school children in Seoul. Throat cultures were taken at the same time to compare ADNase B lovels between S. pyogenes carriers and non-carriers. RESULTS: The distribution of ADNase B concentrations among school children ranged from 77 (detection limit) to 1616 IU/ml and the ULN was estimated to be 362 IU/mL. The carriers of S. pyogenes clad significantly higher ADNase B levels (mean 392 IU/ml) than carriers of non-group A beta-hemolytic streptococci (BHS, 236 IU/ml) oY non-carriers of BHS (234 IU/ml). The relationship between ADNase B (Y) and ASO (X) levels was Y=0.4X+173 (r2=0.209). CONCLUSIONS: The distribution of ADNase B levels showed no close correlation with that of ASO, and ADNase B test was considered to have additive value to ASO test for detecting S. pyogenes infection.
Antistreptolysin ; Child* ; Glomerulonephritis ; Humans ; Nephelometry and Turbidimetry ; Pharynx* ; Rheumatic Fever ; Seoul* ; Streptococcus pyogenes

In recent years, arteriosclerosis obliterans (ASO) has become one of the most common diseases with obesity, high blood pressure and other lifestyle-related diseases such as hyperlipemia. Westernization of the eating habits of the Japanese and progress of the aging society accounts for the increasing occurrence of these health problems. Early detection and early treatment of ASO help not only improve the quality of life of the patients but also get off without amputation of lower limbs and better the prognosis for survival. It is necessary to evaluate the narrowing of blood vessels or the form of occlusion for treatment of ASO. It is particularly important to know the state of the peripheral arteries below the obstructed region in cases with the complete occlusion. Lately, with the addition of many lines to multislice CT (MSCT) and the improvement of the performance of the workstation, angiography for diagnostic purposes has gradually been replaced by MSCT. In this paper, we report two cases of ASO and the successful application of MSCT using 64 Data Acquisition System (DAS) in the examination prior to ASO bypass surgery.
Antistreptolysin O antibody titer ; System ; X-Ray Computed Tomography ; Cases ; seconds

BACKGROUND: Outbreaks of group A streptococcal (GAS) infections have been reported in the military training centers abroad, but bacteriological or epidemiological studies of GAS infections in military recruits inKorea had not yet been done. The aim of this study is to investigate the carrier and status of GAS infections in the Korean military. METHODS: Throat cultures were taken from 180 military recruits before and after training in Nonsan training center in the winter.beta-hemolytic colonies were identified with bacitracin disk and latex agglutination method. Antistreptolysin O (ASO) titers were measured quantitatively for the recruits containing beta- hemolytic streptococci (BHS). Upper limit of normal (ULN) of ASO was calculated from 91 recruits. T and M typing were performed against 24 strains of isolated GAS. RESULTS: BHS were equally isolated from 29 (16.1 %) trainees before and after the training. Of the 29 trainees, 13 (7.2%) carried BHS throughout the training and 16 (10.6%) acquired BHS newly during the training. Three of 5 soldiers carrying GAS showed sustained high ASO levels. The ULN of ASO in the military trainees was 195 IU/ml. T1, M1 (25%) was most frequently identified; T28, M28 (20.8%) and T11, M78 (12.5%) were the next common. CONCLUSION: Although GAS infections did not increase significantly during the training period, the soldiers carrying GAS could become a source of outbreak of GAS infections. Routine benzathine penicillin G chemoprophylaxis for the military recruits is not necessary at the moment, but surveillance of GAS infections should be continued, because M1 type, a rheumatogenic strain, was the most common M type in the military trainees.
Agglutination ; Antistreptolysin ; Bacitracin ; Chemoprevention ; Chungcheongnam-do ; Disease Outbreaks ; Epidemiologic Studies ; Humans ; Latex ; Military Personnel* ; Penicillin G Benzathine ; Pharynx

Authors experienced a case of acute optic neuritis, 12 years old female patient, following scarlet fever which is rare among bacterial origin in ophthalmological aspects. On the first day of admission, the visual acuities of 0.04(N.C.) in right eye and 0.2 (N.C.) in left eye, blurring of disc margins (OU), central scotoma (OD), and high antistreptolysin O titer (A.S.T.O.) were noted. After bed rest and medical treatment with corticosteroid, penicillin, and vitamin B12 for two and a half months, the visual acuities and antistreptolysin O titer were recovered completely.
Antistreptolysin ; Bed Rest ; Child ; Female ; Humans ; Optic Neuritis* ; Penicillins ; Scarlet Fever* ; Scotoma ; Visual Acuity ; Vitamin B 12