The inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report a case of t-AML with inv(16) after combination chemotherapy using antimitotic agent and alkylating agent (cis-platin-paclitaxel) for ovarian serous cystadenocarcinoma.
Antimitotic Agents/*adverse effects/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/*adverse effects/therapeutic use ; Chromosomes, Human, Pair 16/*genetics ; Cisplatin/adverse effects/therapeutic use ; Female ; Humans ; *Inversion, Chromosome ; Leukemia, Myeloid, Acute/*chemically induced/pathology ; Middle Aged ; Taxoids/adverse effects/therapeutic use