Unidirectional valve (UDV) malfunction causes rebreathing of expired gas during anesthesia. However, the resultant hypercarbia without hypoxemia by UDV malfunction is not easily detected. We experienced a case of severe hypercarbia which caused by sticking expiratory valve at 45 minutes after the induction of anesthesia, in spite of checking UDV function preoperatively. In this case, expiratory UDV malfunction was diagnosed with the change of capnographic waveform. And so, we recommend monitoring of capnographic waveform during every anesthesia, in addition to preoperative UDV checking.
Anesthesia ; Anoxia

No abstract available.
Anoxia* ; Neurons*

Hypothesis that hypoxic tumors should be more responsive to the addition of preferential hypoxic cell cytotoxin SR 4233 (tirapazamine) to fractionated irradiation was tested in the mouse SCCVII carcinoma and RIF-1 sarcoma, Model of hypoxic tumor was established using the tumor bed effect; tumors growing in the preirradiated tissue (preirradiated tumors) were more hypoxic than tumors growing in the unirradiated tissue (unirradiated tumors). When the tumors reached a mean volume of 100 mmdegree, both unirradiated and preirradiated tumors were treated with a fractionated course of 62 Gy in 3 days or 8 2.5 Gy in 4days with SR 4233 (0.08 mmlo/kg/injuection) given 30 minutes before each irradiation or without SR 4233. Compared to the unirradiated tumors, hypoxic preirradiated tumors were approximately 5 times more resistant to fractionated irradiation alone but were approximately 5 times more responsive to SR 4233. Addition of SR 4233 potentiated the effect of fractionated irradiation in both unirradiated and preirradiated tumors. Potentiation in the preirradiated tumors was morequal to or greater than that in the unirradiated tumors and seemed to be higher for more fractionated treatment. We confirm the hypothesis in a transplantable mouse tumor. Present results suggest that radioresistance of some hypoxic tumors can be overcome with hypoxic cytotoxin.
Animals ; Anoxia ; Mice ; Sarcoma

Anoxia ; Oxygen* ; Recovery Room*

Animals ; Anoxia* ; Muscles* ; Rats*

No abstract available.
Anoxia* ; Cochlea* ; Diuretics* ; Guinea*

Pulse oximetry is a noninvasive, reusable device that is being used routinely in anesthesia procedure for monitoring oxygen saturation. This is a very beneficial device that can quickly detect of hypoxia, the most common cause of anesthesia-related death. However, in clinical uses, false desaturation readings are frequently found to be caused by various factors. Such as by the use of intraoperative blue dye, which can falsely decrease oxygen saturation as determined by pulse oximetry. We therefore report our findings concerning prolonged decreased pulse oximetry readings due to the intraoperative use of blue dye subcutaneously.
Anesthesia ; Anoxia ; Oximetry* ; Oxygen ; Reading

We have experienced two cases of one lung anesthesia using univent tube for thoracie surgery. One was the bronchoplasty of the right upper lobe. The other was the left pneumonectomy. The movable endobronchial blocker was introduced into the aimed main bronchus applying the "tube rotation method", In the case of brochoplasty, arterial hypoxemia and hypercarbia has not been corrected well because of the partial obstruction of the carina by endobronchial blocker, but the neurologic complications due to these problems were not encountered. No significant problem has been encountered in the pneumonectomy case. Compared with the standard technique using a double lumen endobronchial tube, this method is simple, easy, effective and less traumatous.
Anesthesia* ; Anoxia ; Bronchi ; Lung* ; Pneumonectomy

OBJECTIVE: To investigate the altitude, immigration and suicide rates association in Turkey. METHODS: Suicide and immigration rates of 81 provinces and their elevation data were obtained. RESULTS: There were not significant correlations between country elevation, immigration and mean suicide rate. CONCLUSION: The findings of this study points out that altitude related hypoxia and suicide association may not be generalized and further research will be needed to clarify the effects of altitude on suicide rates.
Altitude ; Anoxia ; Emigration and Immigration ; Suicide ; Turkey

This study was performed to observe the changes of oxygen saturation after tracheal extubation, which depends on the following tracheal extubation methods of the group 1. 2A. 2B, has done. One hundred twenty-five healthy patients that had been selected out of 1~15 year-old at random were divided as follows; Group 1; extubation performed in being awake (n=49) Group 2; anesthetized extubation (n=76) 2A: extubation done in 5 min after discontinuing N2O (n=38) 2B: extubation under anesthesia (GOE or GOF) (n=38) The grouping, which has at random been assigned to the patients, was done just before the end of operation. Oxygen saturation was measured continuously by pulse-oximeter (Minolta Pulsox TS-7, Japan) and was recorded in the process of operation, immediately after extubation and at 1.2.4.6.8.10.20.30 min after extubation while they were spontaneously breathng room air. In case oxygen saturation were less than 90%, supplementary oxygen was administered to them. The frequency of hypoxemia was higher in Group 2 (19.7%) than in Group 1 (10.2%). In group 2B, 2 patients developed severe hypoxemia and 1 patient developed PVC immediately after extubation. Changes of oxygen saturation were as follows; Oxygen saturation in Group 2B was higher than that in Group 1 at each 2 min and 4 min and was also higher than that in Group 2A at 4 min after extubation. As a result, Group 1 is the safest extubation method because of its low risk of hypoxemia. If anestltized extubation must be needed, Group 2A would be preferable to Group 2B method because the frequency of hypoxemia was higher in Group 2B than in Group 2A.In addition, It is suggested that monitoring oxygen saturation continuously by the patients should be safe.
Airway Extubation* ; Anesthesia ; Anoxia ; Humans ; Oxygen*