1.A Case of Congenital Anophthalmos.
Journal of the Korean Ophthalmological Society 1987;28(2):477-482
Anophthalmos is a complete absence of the tissues of the eye. Embryologically, anophthalmos denotes those cases wherein there is complete failure in the outgrowth of the primary optic vesicle. When essential structures of the eye are present, the aonormality is microphthalmos, no matter how small the eye may be. Clinical anophthalmos represents the majority of cases in which the eye appears to be absent. Congenital anophthalmos is one of the rare ophthalmic anomalies, only 5 cases were reported in Korea and about 100 cases in the world. We report this case with a brief review of literatures.
Anophthalmos*
;
Korea
;
Microphthalmos
2.A Case of Congenital Anophthalmos.
Journal of the Korean Ophthalmological Society 1987;28(2):471-475
Congenital anophthalmos is fairly rare malformation in which the eyeball is apparently absent. We experienced a 10-day-old boy, who had a congenital anophthalmos of his left eye, a microphthalmos of the other eye and short palpebral fissure of both eyes(right: 12mm, left: 5mm). The absence of left eyeball within a small orbit was confirmed by C-T scanning. We report this interesting case with a brief review of literatures.
Anophthalmos*
;
Humans
;
Male
;
Microphthalmos
;
Orbit
3.Congenital Anophthalmos Associated with Optic Nerve Aplasia in the Contralateral Eye.
Journal of the Korean Ophthalmological Society 1990;31(4):519-524
Anophthalmos associated with optic nerve aplasia in the contralateral eye is extremely rare. To our knowledge, this is the first case report in Korea. A 3-day-old girl had anophthalmos in the right eye and optic nerve aplasia in the left. Except for the ocular findings, she was relatively healthy. Her sibling had also anophthalmos and expired 4 days after birth. But we could not take her siblings history in detail. We report this case with a brief review of literatures.
Anophthalmos*
;
Female
;
Humans
;
Korea
;
Optic Nerve*
;
Parturition
;
Siblings
4.The Effect of Enucleation in Childhood on Orbital Volumetric Growth.
Kyoung Hoon KOOK ; Jung Bum CHOI ; Mi In ROH ; Sang Yeul LEE
Journal of the Korean Ophthalmological Society 2004;45(11):1790-1798
PURPOSE: To evaluate the effect on the growth rate of orbital volume of those who received enucleation or evisceration with or without implants, according to different sizes and operation periods. METHODS: The subjects comprised 47 patients who had previously undergone evisceration or enucleation. The volumes of both anophthalmic and normal orbit were measured from CT scans of patients and compared. The relationship between the orbital volume growth rate and the operation at young age with different size implants or operation without implants was evaluated. RESULTS: Five groups, divided by age at operation, were evaluated. Four groups comprising under 12 years of age, had a significant delay in orbital volume growth development (p<0.05). Three groups, divided by size of implants, were evaluated and 17 mm or smaller sized orbital implants showed significant orbital volume growth retardation (p<0.05) CONCLUSIONS: The effect of early enucleation on orbital volume growth should be considered in patients younger than 12 years old. Furthermore, during the operation, implants with sizes larger than 18mm should be used to prevent the retardation of orbital volume growth.
Anophthalmos
;
Child
;
Humans
;
Orbit*
;
Orbital Implants
;
Tomography, X-Ray Computed
5.Two case of Congenital Anophthalmos.
Kyung Sup SOHN ; In Sun SHIN ; Jae Ho KIM ; Sang Min KIM ; Kyung Sub SHIN
Journal of the Korean Ophthalmological Society 1969;10(1):11-13
Authors observed clinically for congenital anophthalmos in two cases. One case was a boy, aged 6 years, having congenital anophthalmos of right eye with bifid uvula and another case was newbron baby, aged 4 days, having congenital anophthalmos and blepharophimosis of left eye and was born to undernutciented mother from chronic hepatitis.
Anophthalmos*
;
Blepharophimosis
;
Hepatitis, Chronic
;
Humans
;
Male
;
Mothers
;
Uvula
6.Morphological Study of a New Orbital Implant: Hydroxyapatite-Coated Porous Alumina in Rabbit.
Youl Seok SEONG ; Sang Yeul LEE ; Sung Joo KIM
Journal of the Korean Ophthalmological Society 2001;42(9):1354-1361
PURPOSE: We evaluated the morphologic change of the hydroxyapatite(HA)-coated porous alumina as a new orbital implant when it was used in rabbit. METHODS: After evisceration of 18 eyes of 18 New Zealand white rabbits, we implanted 12 mm-diameter-sized HA-coated porous alumina with different pore sizes; 300, 500, and 800 micrometer, and then the implants were extracted back to evaluate their morphologic change according to different time interval; 2, 4, and 12 weeks. RESULTS: Fibrovascularization was noted at periphery of the implant 2 weeks after implantation in all of the three groups, and to the center of the implant 4 and 12 weeks after implantation. This fibrova-scularization was most predominant in 500 micrometerpore-sized group compared to the rest two groups. CONCLUSIONS: HA-coated porous alumina showed similar appearance of fibrovascularization with relatively more affordable price and easy manufacture, compared to the other porous implants.
Aluminum Oxide*
;
Anophthalmos
;
Durapatite
;
Orbit*
;
Orbital Implants*
;
Rabbits
7.Surgical Outcomes of Porcine Acellular Dermis Graft in Anophthalmic Socket: Comparison with Oral Mucosa Graft.
Livia TEO ; Young Jun WOO ; Dong Kyu KIM ; Chang Yeom KIM ; Jin Sook YOON
Korean Journal of Ophthalmology 2017;31(1):9-15
PURPOSE: We describe our experience with the Permacol graft in anophthalmic socket reconstruction, and compare it to the autologous buccal mucosal graft, emphasizing the postoperative vascularization and contraction of each graft. METHODS: This was a retrospective comparative study. We measured the time necessary for the graft surface to be completely vascularized, as well as the fornix depth of the conjunctival sac in anophthalmic patients. RESULTS: Ten patients underwent Permacol graft reconstruction, with 44 undergoing buccal mucosal graft reconstruction. Seven eyelids (70%) in the Permacol group had a good outcome, with improvement in lower eyelid position and prosthesis retention. Nine out of 10 eyelids (90%) in this group showed complete vascularization of the graft at 2.6 ± 1.9 months postoperatively, while the grafted buccal mucosa was fully vascularized at 1.1 ± 0.3 months postoperatively (p < 0.01). Postoperative fornix depth in the Permacol group was 9.1 ± 2.2 mm, compared to 14.9 ± 4.5 mm in the buccal mucosal graft group (p < 0.01). Mean increases in fornix depth were 33.1% and 67.9% of the mean vertical length of the implanted graft. CONCLUSIONS: The Permacol graft can be useful as spacer graft material in anophthalmic socket patients. It takes longer to vascularize, and undergoes greater graft shrinkage with time, compared to the buccal mucosal graft.
Acellular Dermis*
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Anophthalmos
;
Eyelids
;
Humans
;
Lacrimal Apparatus
;
Mouth Mucosa*
;
Prosthesis Retention
;
Retrospective Studies
;
Transplants*
8.Nonsurgical Treatment for The Socket of Congental Microphthalmos.
Jae Hyun NOH ; Jong Wook HONG ; Tae Soo LEE
Journal of the Korean Ophthalmological Society 1995;36(9):1610-1617
Anophthalmos or microphthalmos is a rare congenital anomaly in which there is an absence of ocular tissue or small eyeball. This anomaly results in a small bony orbit and deformity of the asssociated skeletal, and soft tissues. Conventional management of the anophthalmic or microphthalmic orbit is started with the intraorbital placement of progressively increasing conformers as early as possible without enucleation. If an early treatment was not started, there could be retardation of growth of bony orbit and ipsilateral facial hypoplasia which is a necessity of more complex, disappointing application of three dimensional expansion osteotomy and socket reconstruction. The goal of treatment is the insertion of a comfortable prosthesis with good cosmesis. We treated 3 microphthalmic patients, who could not insert prosthesis on the first visit. We inserted an acrylic conformer into the orbit and then exchanged at interval of 6-8 weeks in order to expand the orbit. We obtained good cosmetic results. and the parents of patients were pleased with the appearance of their children fitting prosthesis.
Anophthalmos
;
Child
;
Congenital Abnormalities
;
Humans
;
Microphthalmos*
;
Orbit
;
Osteotomy
;
Parents
;
Prostheses and Implants
9.Comparison of Bacterial Culture Rate and Bacterial Floral Distribution in Anophthalmic Patients with Prosthetic Eye, Between Patients with Symptom and Without Symptom.
Journal of the Korean Ophthalmological Society 2013;54(4):552-556
PURPOSE: To evaluate the distribution of conjunctival bacterial flora in anophthalmic socket patients with a prosthetic eye, and compare the bacterial positive culture rates between patients with subjective symptoms such as eye wax or irritation and patients without symptoms. METHODS: Twenty-six anophthalmic socket patients with a prosthetic eye who visited our clinic between December 2009 and May 2011 were retrospectively analyzed. The patients were asked about their symptoms, followed by a conjunctiva examination. Specimens were obtained from the inferior conjunctival cul- de- sac with a sterile cotton-tipped applicator. The collected specimens were cultured. RESULTS: The results indicated that the overall positive culture rate in the anophthalmic conjunctival socket was 69.2%, and the predominant organism was S. epidermidis (38.5%). Potential pathogenic bacteria were found in 4 eyes with a 15% positive culture rate. The incidence of bacteria was significantly higher (85.4%) in patient samples with subjective symptoms compared to patients without symptoms (50%). The bacterial positive culture rate of the potential pathogen bacteria in the group with symptoms was higher at 21%, but was not statistically significant. CONCLUSIONS: Performing a pathogen culture test is necessary for prosthetic eye patients who complain of their symptoms. Additionally, the proper antibacterial treatment should be performed according to the antibiotics sensitivity of cultured bacteria.
Anophthalmos
;
Anti-Bacterial Agents
;
Bacteria
;
Conjunctiva
;
Eye
;
Humans
;
Incidence
;
Retrospective Studies
10.Medpor(r) Enophthalmos Wedge Implants in Enophthalmos Correction.
Byoung Jin KIM ; Yoon Duck KIM
Journal of the Korean Ophthalmological Society 2002;43(9):1559-1569
PURPOSE: We assessed the effect of Medpor(r) enophthalmos wedge implant on the correction enophthalmos. METHODS: Authors operated on 12 patients with enophthalmos using Medpor(r) enophthalmos wedge implant. RESULTS: Among 12 cases, 5 were men and 7 were women. Average age was 37.2 years. Average followup period was 8.1 months. There were posttraumatic enophthalmos in 8 patients and anophthalmic enophthalmos in 4 patients. We used 27 implants to correct enophthalmos (mean 2.3 implants). Among 8 orbital fracture cases, ocular motility disturbance and diplopia were improved in 7 cases. The amount of enophthalmos corrected was between 1 and 5 mm (mean 3.1 mm). We experienced improvement of inferior dystopia (mean 2.1 mm) in 11 cases and medial dystopia (mean 0.8 mm) in 5 cases. There was no case of visual loss, implant infection, migration, or exposure. CONCLUSIONS: Our results showed that Medpor(r) enophthalmos wedge implant effectively corrected enophthalmos without significant complications.
Anophthalmos
;
Diplopia
;
Enophthalmos*
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Orbital Fractures