Tufts folliculitis is an uncommon folliculitis of the scalp that resolves with patches of scarring alopecia within which multiple hair tufts emerge from dilated follicular orifices. Each tuft consists of 5 to 20 normal-appearing hairs arising from a single follicular orfice. It has a prolonged relapsing clinical course, and results in a scarring alopecia. Systemic antibiotics and steroids are commonly used for anti-inflammatory effects, but have only a brief response. Here, we report a case of tufted hair folliculitis in a 36-year-old woman, with the clinical, histological findings and computerized hand-held phototrichogramical evaluations.
Adult ; Alopecia ; Anti-Bacterial Agents ; Cicatrix ; Female ; Folliculitis ; Hair* ; Humans ; Scalp ; Steroids

Papular elastorrhexis is a rare disease, characterized by multiple nonfollicular white papules that usually occur on the trunk. Papular elastorrhexis occurs during childhood and adolescence. Histopathologically, the elastic fibers are decreased and they may appear in thin and fragmented forms. Herein, we report a 20-year-old Korean woman with asymptomatic multiple nonfollicular white firm papules that were scattered over the anterior chest.
Adolescent ; Elastic Tissue ; Female ; Humans ; Rare Diseases ; Thorax ; Young Adult

Acquired Blaschko dermatitis is a rare inflammatory linear eruption that presents as multiple lines of itching papules and vesicles following the Blaschko's lines. Only ten cases have been reported in literatures since Grosshans' first description in 1990 and all cases have been in adults. A 2-year-old girl presented with a 4-month history of a slightly pruritic papulovesicular eruption, which was limited to the left side of her body, along the Blaschko's line. A skin biopsy revealed interface dermatitis. The eruption initially failed to respond to treatment with topical steroids but responded to systemic steroids. We present the first case of acquired Blaschko dermatitis in a child with a review of the relevant literature.
Adult ; Biopsy ; Child* ; Child, Preschool ; Dermatitis* ; Female ; Humans ; Lichens* ; Pruritus ; Skin ; Steroids

We report a case of intratumoral fat in neurofibroma and coexistance of eccrine hidrocystoma on the occipital area of the scalp for one year duration. There are several diseases showing fatty change histopathologically. Among them, few cases of neurofibroma showing fatty change had been reported. The mechanism of fatty change is unclear, but several hypotheses are proposed. Here we report a case of neurofibroma showing fatty change and coexistence of eccrine hidrocystoma, and discuss the pathomechanism of fatty change and its relationship with disease.
Hidrocystoma* ; Neurofibroma* ; Scalp

Gefitinib (Iressa, ZD1839) is one of the epidermal growth factor receptor (EGFR) inhibitors approved for the treatment of advanced non-small cell lung cancer. The cutaneous reactions to EGFR inhibitors manifest as a follicular eruption, nail toxicity, xerosis, or desquamation. These adverse events, if not properly managed, can interfere with activities of daily living. We report a case of paronychia induced by gefitinib successfully treated with cryosurgery which is a simple and safe treatment.
Activities of Daily Living ; Carcinoma, Non-Small-Cell Lung ; Cryosurgery ; Paronychia* ; Receptor, Epidermal Growth Factor

Folliculosebaceous cystic hamartoma is a rare cutaneous hamartoma comprised of follicular, sebaceous, and mesenchymal elements. It usually presents as an exophytic papule or nodule on the central part of the face. The histological findings are intradermal cystic structures lined by infundibular epithelium, numerous sebaceous lobules radiating from cystic structures and a surrounding stroma composed of mesenchymal changes, including variable proportions of fibrous, adipose, vascular and neural tissues. We herein report a case of folliculosebaceous cystic hamartoma in a 73-year-old man who presented with a skin-colored, dome-shaped papule on the right nasal ala.
Aged ; Epithelium ; Hamartoma* ; Humans

The lead of a pencil is composed of graphite and clay. Although considered as biologically inert for a long time, the lead of a pencil can result in undesirable local pain, pigmentation, abscess formation and graphite foreign body reaction. Therefore, all penetrating injuries caused by a pencil should be carefully assessed and treated in order to remove all pieces of lead from the wound by specialized paramedics or medical doctors. We should be aware that graphite granules embedded in the skin may give rise to clinically alarming delayed reactions. Here we present a 19-year-old woman with a foreign body, the lead of a pencil, misdiagnosed as a blue nevus.
Abscess ; Allied Health Personnel ; Female ; Foreign Bodies* ; Foreign-Body Reaction ; Granuloma ; Graphite* ; Humans ; Nevus, Blue* ; Pigmentation ; Skin ; Wounds and Injuries ; Young Adult

Neuroendocrine carcinoma is known to have features of neuroendocrine and epithelial differentiation through immunohistochemical and biochemical investigation. Cutaneous metastatic neuroendocrine carcinoma must be differentiated from Merkel cell carcinoma, a primary cutaneous neuroendocrine carcinoma and metastatic carcinoma from other visceral disease. Cutaneous metastases from neuroendocrine carcinomas of a variety of sites including the uterus, vulva, gall bladder and fallopian tubes have been reported. We report a 58-year-old Korean man with a metastatic skin tumor on his scalp from rectal neuroendocrine carcinoma.
Carcinoma, Merkel Cell ; Carcinoma, Neuroendocrine* ; Fallopian Tubes ; Female ; Humans ; Middle Aged ; Neoplasm Metastasis* ; Neuroendocrine Tumors ; Rectum* ; Scalp ; Skin* ; Urinary Bladder ; Uterus ; Vulva

Chemotherapy-induced acral erythema (CIAE) is a toxic reaction to a number of different chemotherapeutic agents, and causes symmetrical, well-demarcated, painful erythema on the palms and soles which is self-limiting. CIAE with bullous reaction in relation to methotrexate has been reported, but it is more commonly associated with cytosine arabinoside. The differential diagnosis of this condition from more serious conditions such as graft-vs-host disease or toxic epidermal necrolysis is essential. In this paper, we report the case of a 65-year-old man who developed bullous acral erythema after the administration of high-dose methotrexate for the treatment of Non-Hodgkin's lymphoma.
Aged ; Cytarabine ; Diagnosis, Differential ; Erythema* ; Graft vs Host Disease ; Hand-Foot Syndrome ; Humans ; Lymphoma, Non-Hodgkin ; Methotrexate ; Stevens-Johnson Syndrome

Lichen striatus (LS) is a self-resolving condition, which may occasionally need treatment for significant pruritus, a persistent course or cosmetic problems. The options for treatment have usually been topical or intralesional corticosteroids, salicylic acid, coal tar, or more recently, topical tacrolimus and pimecrolimus. We report a case of LS successfully treated with pimecrolimus in a 15-year-old girl.
Adolescent ; Adrenal Cortex Hormones ; Coal Tar ; Female* ; Humans ; Lichens* ; Pruritus ; Salicylic Acid ; Tacrolimus