1.Cytotechnologists and On-Site Evaluation of Adequacy.
Jennifer A COLLINS ; Anna NOVAK ; Syed Z ALI ; Matthew T OLSON
Korean Journal of Pathology 2013;47(5):405-410
While fine needle aspiration (FNA) is certainly not a new biopsy technique, recent developments in advanced imaging techniques, molecular testing, and targeted therapies have coincided with a rapid increase in the number of FNA procedures being performed. Concurrently, the demand for on-site evaluation of adequacy (OSEA) has also increased, outstripping the capacity of available cytopathologists at some institutions. Among the several alternatives to cytopathologist-performed OSEA, cytotechnologist-attended OSEA stands out because it preserves the representation of the pathology service at the time of the procedure. Herein, we review the current literature about OSEA and the necessity of cytotechnologists to expand access of this useful pathology service to a broader patient population. We also examine how cytotechnologists are likely to fit into the emerging practice of telecytology.
Biopsy
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Biopsy, Fine-Needle
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Humans
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Telepathology
2.Liver Graft Failure and Bile Cast Nephropathy
Anna MRZLJAK ; Zeljka JUREKOVIC ; Rafaela NOVAK ; Bojana MAKSIMOVIC ; Danko MIKULIC ; Danica GALESIC LJUBANOVIC
The Korean Journal of Gastroenterology 2020;75(3):167-171
The consequences of graft failure after liver transplantation (LT) range far beyond the liver. The kidneys are often affected, where persistent and progressive cholestasis can result in acute kidney injury (AKI) leading to the development of bile cast nephropathy (BCN). BCN is an often unrecognized condition that is characterized by proximal tubulopathy and the formation of bile casts in the distal tubules, which is almost diagnosed exclusively on a kidney biopsy or autopsy. This condition is potentially reversible, provided the bilirubin levels can be reduced early. LT may represent a treatment option in the case of irreversible liver (or liver graft) failure, which is beneficial for both the liver and the kidney. This paper reports a case of BCN in a patient with idiopathic graft failure after LT. Despite his chronic kidney disease, liver re-transplantation led to the successful improvement of his AKI.