PURPOSE: To evaluate the clinical interpretation and application of Teller Acuity Card(TAC) test compared with optotype acuity chart in the diagnosis of amblyopia. METHODS: The visual acuities of 112 children(54 normal, 58 amblyopes), whose mean age was 6.5 years(3~11 years) were measured with Han's letter chart and TAC. The sensitivity, specificity, false-positive and false-negative rates of TAC Test were analyzed according to the visual acuity, age and type of amblyopia. RESULTS: TAC acuity was higher than optotype acuity in both strabismic and anisometropic amblyopia group, however, the anisometropic amblyopia group showed higher correlation between two tests(P<0.01,r=0.0755). The sensitivity and specificity of TAC test increased in lower visual acuity group, which means that TAC test is useful in detecting amblyopia. While the false-positive rate increased in higher visual acuity group, false-negative rate increased in lower visual acuity group and in the group less than 6 years of age. And the bilateral visual acuity were underestimated than unilateral visual acuity in about 30%. CONCLUSIONS: Though TAC test is a useful method in detecting amblyopia of infancy and childhood, an appropriate clinical diagnosis should be accompanied for the accurate diagnosis of amblyopia.
Amblyopia* ; Anisometropia ; Diagnosis* ; Sensitivity and Specificity ; Strabismus ; Visual Acuity

We retrospectively reviewed the medical records of 282 consecutive patients with the diagnosis of exotropia and analyzed the clinical factors related to amblyopia. The average age was 4.8 years old(138 males, 144 females). The results of analysis run as follows. First, in exotropia, the prevalence of the amblyopia was 19.8%, the detection of exotropia in the group with amblyopia was earlier than the group without (p<0.05), the degree of anisometropia was greater, the prevalence of significant anisometropia(more than 1.0 diopter in spherical equivalent) was higher. Second, The presence of amblyopia and the degree of correction of amblyopia before the surgery did not relate with the surgical success rate. Third, the recurrence rate of cured amblyopia after termination of occlusion therapy was 10.8%, the recurrence rate and the developement of amblyopia after surgery were 11.2%, 5.5% respectively. In orthotropia and esotropia after surgery, the recurrence rate of amblyopia and development of amblyopia were high.
Amblyopia* ; Anisometropia ; Child* ; Diagnosis ; Esotropia ; Exotropia* ; Humans ; Male ; Medical Records ; Prevalence ; Recurrence ; Retrospective Studies

PURPOSE: To investigate the trend of refractive change in hyperopic patients according to increases in age. METHODS: Eighty-eight children who had hyperopia of more than +1.50 diopters (D) and could be followed up for at least 5 years were included in this study. We divided the patients into two groups according to the level of initial hyperopia and retrospectively analyzed hyperopic refractive changes over a 5-year period according to age at initial diagnosis, presence of esotropia, amblyopia, astigmatism and anisometropia. RESULTS: We gained the following formula about the aspect of hyperopic reduction in 88 patients over a period of 5 years: Diopter (D)=7.99-2.14 Ln (age). The presence of anisometropia and amblyopia did not affect hyperopic reduction. Hyperopic reduction amounts in the group with a hyperopic eye of more than +5D at initial diagnosis were greater than in the group with a hyperopic eye less than +5D, and greater in the group with an astigmatic eye of more than 1D. The presence of esotropia and the age at initial diagnosis did not affect hyperopic reduction. CONCLUSIONS: We show that emmetropization in hyperopic children occurs according to the following formula: Diopter (D)=7.99-2.14 Ln (age). Both the initial level of hyperopia and the concurrent presence of astigmatism affected hyperopic reduction. However, the presence of anisometropia, amblyopia, esotropia and the age at initial diagnosis did not significantly affect hyperopic reduction.
Amblyopia ; Anisometropia ; Astigmatism ; Child ; Diagnosis ; Esotropia ; Follow-Up Studies* ; Humans ; Hyperopia ; Retrospective Studies

PURPOSE: To compare the thickness of superior, temporal, inferior, and nasal macula and foveal thickness and volume in patients with anisometropic amblyopia prior to and after successful occlusion therapy using optical coherence tomography (OCT) measurement. METHODS: Data were collected prospectively on 30 patients with unilateral anisometropic amblyopia from December 2006 to August 2007. All patients had anisometropia of 2.0 diopters or more. OCT scans were obtained for all patients at diagnosis. Occlusion therapy was then prescribed and OCT scans were obtained again at the time of successful occlusion therapy (defined as interocular difference of <0.1 log units). The Stratus OCT-3 was used to measure fovea thickness and volume and the thickness of superior, temporal, inferior, and nasal macula (within a diameter of 3 mm). RESULTS: Of 30 patients, 22 (mean age of 5.8 years) had successful resolution of amblyopia. The mean duration of occlusion was 11.24 months and mean best-corrected visual acuity at diagnosis was 0.35 ± 0.12 logarithm of the minimum angle of resolution. The mean thicknesses of the superior, temporal, inferior, and nasal macula prior to and after occlusion were not significantly different (p > 0.05). However, mean foveal volume prior to occlusion therapy (0.15 ± 0.02 mm3) decreased after occlusion (0.14 ± 0.01 mm3) with statistical significance (Wilcoxon signed rank test, p = 0.025). CONCLUSIONS: There was a meaningful decrease in foveal volume in patients with anisometropic amblyopia after successful occlusion therapy. Whether this decrease relates to visual improvement of the amblyopic eye remains to be determined.
Amblyopia ; Anisometropia ; Diagnosis ; Humans ; Prospective Studies ; Tomography, Optical Coherence ; Visual Acuity

PURPOSE: To prevent permanent visual disturbance, we performed a mass screening for the detection of ocular disorders of preschool children. METHODS: Ocular examination was performed on 33,955 children in Seou(3~6 years of age)l, during the period from January to December, 2000. 435 children were shown to have either visual acuity of less than 0.5 or anisometropia of over 2 lines. Detailed Eye examination. was conducted on those 435 children. RESULTS: Diagnoses consisted of refractive errors in 325(74.7%), amblyopia in 91(20.9%), strabismus 21(4.8%) and anterior segment abnormalities in 34(7.8%). Among th types of refractive errors, hyperopic astigmatism 98(30.4%) was the most common type. Astigmatism was combined with all other types in 257(79.9%) children. In cases of strabismus, exotropia was 12(57.1%) and esotropia was 4(19.0%). Refractive error was the most common cause of amblyopia(88(96.7%)). CONCLUSIONS: To prevent and treat amblyopia or strabismus, easily detection and adequate care at preschool age seemed to be very effective. Participation rate for this mass-screening of eye disease during preschool age will be more increased by efforts of constitutional support and parental coperation.
Amblyopia ; Anisometropia ; Astigmatism ; Child* ; Child, Preschool ; Diagnosis ; Esotropia ; Exotropia ; Eye Diseases ; Humans ; Mass Screening ; Parents ; Refractive Errors ; Seoul* ; Strabismus ; Vision Screening* ; Visual Acuity

PURPOSE: To inform the necessity of mass screening, we performed a mass screening for the detection of ocular disorders of preschool children. METHODS: Ocular examination was performed on 60, 827 children in Korea (3-6 years of age) during the period from March to October, 2000. The total of 3, 254 children were shown to have either visual acuity of less than 0.5 or anisometropia of over 2 lines. Detailed eye examination was conducted on those 3, 254 children. RESULTS: The numbers of first mass screening were 60, 826. Diagnosis consisted of refractive errors in 2, 216, amblyopia in 664, and strabismus in 235. Among the types of refractive errors, myopic astigmatism was the most common type (34.0%). Astigmatism was combined with all other types in 1, 659 children. Refractive error was the most common cause of amblyopia (88.0%) CONCLUSIONS: To prevent and treat amblyopia or strabismus, early detection and adequate care at preschool age seemed to be very effective. Participation rate for this mass-screening of eye disease during preschool age will be more increased by efforts of constiutional support and parental cooperation.
Amblyopia ; Anisometropia ; Astigmatism ; Child* ; Child, Preschool ; Diagnosis ; Eye Diseases ; Humans ; Korea* ; Mass Screening ; Parents ; Refractive Errors ; Strabismus ; Vision Screening* ; Visual Acuity

PURPOSE: To investigate horizontal image disparity in three-dimensional (3-D) perception using 3-D animations in normal control patients and patients with intermittent exotropia, anisometropic amblyopia, and partially accommodative esotropia. MATERIALS AND METHODS: A total of 133 subjects were included. Stereopsis was measured using the Titmus Stereo test (Stereo Optical Inc., Chicago, IL, USA) and a 3-D stereopsis test with a 15 inch 3-D display laptop, adjusting 3-D parameters of 0 mm horizontal disparity to 15 mm horizontal disparity. RESULTS: When compared with normal controls, the average threshold of the 3-D stereopsis test was significantly reduced for esotropia patients (p<0.001) and for anisometric amblyopia patients (p<0.001), compared to normal controls. No significant difference was observed between normal controls and intermittent exotropia patients (p=0.082). The 3-D stereopsis test was correlated with the Titmus Stereo test (Spearman's rho=0.690, p<0.001). Mean difference in stereoacuity was 1.323 log seconds of arc (95% limits of agreement: 0.486 to 2.112), and 125 (92.5%) patients were within the limits of agreement. CONCLUSION: This study demonstrated that a 3-D stereopsis test with animation is highly correlated with the Titmus Stereo test; nevertheless, 3-D stereopsis with animations generates more image disparities than the conventional Titmus Stereo test. The 3-D stereopsis test is highly predictive for estimating real stereopsis in a 3-D movie theater.
Adult ; Aged ; Amblyopia/diagnosis ; Anisometropia/diagnosis ; *Depth Perception ; Esotropia/diagnosis ; Female ; Humans ; Imaging, Three-Dimensional/*instrumentation ; Male ; Middle Aged ; *Perceptual Disorders ; Software ; *Vision Disparity ; Vision, Binocular ; Visual Acuity/*physiology