1.CFTR, a rectifying, non-rectifying anion channel?.
Journal of Korean Medical Science 2000;15(Suppl):S17-S20
No abstract available.
Adenosine Triphosphate/pharmacology
;
Anions/metabolism
;
Bicarbonates/metabolism*
;
Chlorides/metabolism*
;
Cyclic AMP/pharmacology
;
Cystic Fibrosis Transmembrane Conductance Regulator/physiology*
;
Electric Conductivity
;
Electrophysiology
;
Gluconates/pharmacology
;
Human
;
Membrane Potentials/physiology
;
Membrane Potentials/drug effects
;
Potassium/pharmacology
;
Sweat Glands/metabolism*
2.Dustfalls and Various Ion Concentrations in Their Filtrates in an Urban and in a Rural Districts.
Korean Journal of Preventive Medicine 1985;18(1):59-72
During a period from February 1st to November 30th in 1983, measurements were made twice a month on dustfalls and concentrations of various cations and anions in their filtrates in an urban (Heuksuk-dong, Seoul) and in a rural (Ansung) districts. Standard British Deposit Gauge method was applied for collection of dustfalls and ion chromatographic method using Ion Chromatograph 10 (Dionex, U.S.A.) for determination of cation and anion concentrations. The results obtained were as follows: 1. Annual mean values of dustfalls were 8.30+/-5.09 tons/km2/month in an urban and 6.20+/-0.82 tons/km2/month in a rural districts. And annual mean values of pH of filtrates of the collected samples were 5.3+/-0.76 in an urban and 6.0+/-0.82 in a rural districts. 2. Annual mean concentrations of common cations and anions in their filtrates were as follows: Some of anions such as Br-, PO4-3 and NO2 were scarcely detected and F was measured at very low concentrations ranging from 0.1 to 0.5 ppm in Feb., Oct. and Nov. in an urban and in Feb. in a rural districts. 3. By two-way analysis of variance with 4 replications for dustfalls, pH and concentrations of various ion by district and month of a year, statistically significant differences were noted in dustfalls (p<0.01), pH (p<0.01) and concentrations of various ion (p<0.01) by month of a year, and in dustfalls (p<0.05) and concentrations of various ion such as NH4, Ca, NO3 and SO4 (p<0.01) by district. 4. There were statistically significant differences pH in Spring (Feb., Mar. and Apr.) (p<0.01) and in SO4 in Autumn (Aug., Sept., Oct. and Nov.) (p<0.05) between the two districts.
Anions
;
Cations
;
Hydrogen-Ion Concentration
3.Bleaching effect of carbamide peroxide gel on discolored nonvital teeth.
Sun Ah PARK ; Sun Ho KIM ; Yun Chan HWANG ; Byung Ju OH ; Chang YOUN ; Yeong Joon PARK ; Sun Wa JEONG ; In Nam HWANG ; Won Mann OH
Journal of Korean Academy of Conservative Dentistry 2002;27(4):441-447
The bleaching of discolored nonvital teeth is conservative treatment that satisfy the cosmetic desire. The most common method for this treatment, walking bleaching, is using 30% hydrogen peroxide and sodium perborate. Many alternatives are suggested for preventing the external cervical root resorption that is the common complication of the nonvital teeth bleaching with 30% hydrogen peroxide. The same extent of oxidation reactions as that resulted by the bleaching with the application of 30% hydrogen peroxide and sodium perborate can also be acquired more safely by materials that contain 10% carbamide peroxide, used primarily for the bleaching of vital teeth. Therefore, this study was performed to evaluate the efficacy of 10% and 15% carbamide peroxide bleaching gel in nonvatal teeth bleaching. The internal bleaching of intentionally discolored teeth was performed in vitro with 10% carbamide peroxide (Group 1), 15% carbamide peroxide (Group 2), mixture of distilled water and sodium perborate (Group 3), and mixture of 30% hydrogen peroxide and sodium perborate (Group 4). The bleaching materials were refreshed following 3, 6, 9 and 12 days. To evaluate the bleaching effect, the color change of the crowns was measured at 1, 2, 3, 4, 7 and 15 days of bleaching using the colorimeter. The results were as follows : 1. L* and DeltaE* values were increased with time in all bleaching agents(p<0.01). 2. There was no significant difference in L* and DeltaE* value among bleaching agents. 3. DeltaE* value higher than 3 was shown after 3 days of bleaching with 10% carbamide peroxide gel, 1 day with 15% carbamide peroxide gel, 4 days with mixture sodium perborate and distilled water and 4 days with mixture sodium perborate and 30% hydrogen peroxide, respectively. These results revealed that the use of 10% and 15% carbamide peroxide bleaching gel in non-vital teeth bleaching is as effective as mixture of distilled water and sodium perborate and mixture of 30% hydrogen peroxide and sodium perborate. Accordingly, carbamide peroxide could be used clinically to bleach discolored non-vital teeth.
Borates
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Cosmetics
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Crowns
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Hydrogen
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Hydrogen Peroxide
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Intention
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Peroxides
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Root Resorption
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Sodium
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Tooth
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Tooth Bleaching
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Tooth, Nonvital
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Urea
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Walking
;
Water
4.Protein and Lipid Oxidation of the Skin Induced by Ultraviolet A-Irradiation of White Mice.
Young Pio KIM ; Seung Churl LEE ; Inn Ki CHUN
Annals of Dermatology 1989;1(1):16-20
No abstract available.
Animals
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Lipid Peroxides
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Mice*
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Skin*
5.A Comparison of the irrigation systems in calcium hydroxide removal.
Jae Seung EUN ; Se Hee PARK ; Kyung Mo CHO ; Jin Woo KIM
Journal of Korean Academy of Conservative Dentistry 2009;34(6):508-514
The purposes of this study were to compare the efficacy of irrigation systems by removing a calcium hydroxide (Ca(OH)2) paste from the apical third of the root canal and the effect of the patency file. Sixty single rooted human teeth were used in this study. The canals were instrumented by a crown-down manner with .04 taper ProFile to ISO #35. Ca(OH)2 and distilled water were mixed and placed inside the root canals. The teeth were divided into 6 groups according to the root canal irrigation system and the use of patency file as follows: group 1 - conventional method; group 2 - EndoActivator(R); group 3 - EndoVac(R); group 4 - conventional method, patency; group 4 - EndoActivator(R), patency; group 6 - EndoVac(R), patency. All teeth were irrigated with sodium hypochlorite. After the root canal irrigation, the teeth were split in bucco-lingual aspect. Percentage of the root canal surface coverage with residual Ca(OH)2 until 3 mm from working length was analyzed using Image Pro Plus ver. 4.0. Statistical analysis was performed using the One-way ANOVA, t-test and Scheffe's post-hoc test. Conventional groups had significantly more Ca(OH)2 debris than EndoActivator(R), EndoVac(R) groups. There was no significant difference between EndoActivator(R) and EndoVac(R) groups. Groups with patency file showed more effective in removing Ca(OH)2 paste than no patency groups, but, it was no significant difference. This study showed that EndoActivator(R) and EndoVac(R) systems were more effective in removing Ca(OH)2 paste from the apical third of the root canal than conventional method.
Calcium
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Calcium Hydroxide
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Dental Pulp Cavity
;
Humans
;
Hydroxides
;
Sodium Hypochlorite
;
Tooth
;
Water
6.Degumming of kenaf fibers by combining steam explosion with ultrasonic treatment.
Xiao ZHANG ; Guangting HAN ; Yuanming ZHANG ; Qijun WANG ; Wei JIANG ; Shouwu GAO
Chinese Journal of Biotechnology 2014;30(5):734-742
Kenaf has a high content of gum that is difficult to remove. Traditional chemical degumming process causes serious environmental pollution. To solve the problem, we developed a new method to degum kenaf. We pretreated the kenaf with steam explosion followed by ultrasonic treatment. We chose the single factor tests to select the ultrasonic frequency, sodium hydroxide concentration and processing time. Combined with orthogonal tests, we found that the optimum conditions were as follows: ultrasonic frequency was 28 kHz, sodium hydroxide concentration was 2%, and processing time was 60 min. Under these conditions, the residual gum of kenaf fiber was 9.72% and the fineness was 139.45 N(m). Steam explosion combined with ultrasonic method is effective in degumming of kenaf.
Hibiscus
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Plant Gums
;
isolation & purification
;
Sodium Hydroxide
;
chemistry
;
Steam
;
Ultrasonics
7.Too much salt, too little soda: cystic fibrosis.
Acta Physiologica Sinica 2007;59(4):397-415
Cystic fibrosis (CF) of the pancreas is the most widely accepted name of the most common fatal inherited single gene defect disease among Caucasians. Its incidence among other races is thought to be significantly less, but mutations in the gene have been reported in most, if not all, major populations. This review is intended to give general concepts of the molecular as well as physiological basis of the pathology that develops in the disease. First, an overview of the organ pathology and genetics is presented, followed by the molecular structure of the gene product (cystic fibrosis transmembrane conductance regulator, CFTR), its properties, functions, and controls as currently understood. Second, since mutations appear to be expressed primarily as a defect in electrolyte transport, effects and mechanisms of pathology are presented for two characteristically affected organs where the etiology is best described: the sweat gland, which excretes far too much NaCl ("salt") and the pancreas, which excretes far too little HCO3(- )("soda"). Unfortunately, morbidity and mortality in CF develop principally from refractory airway infections, the basis of which remains controversial. Consequently, we conclude by considering possible mechanisms by which defects in anion transport might predispose the CF lung to chronic infections.
Anions
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metabolism
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Bicarbonates
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Cystic Fibrosis
;
physiopathology
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Cystic Fibrosis Transmembrane Conductance Regulator
;
metabolism
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Humans
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Ion Transport
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Pancreas
;
physiopathology
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Sodium Chloride
;
Sweat Glands
;
physiopathology
8.Clinical Usefulness of the Serum Anion Gap.
Sik LEE ; Kyung Pyo KANG ; Sung Kyew KANG
Electrolytes & Blood Pressure 2006;4(1):44-46
The anion gap in the serum is useful in the interpretation of acid-base disorders and in the diagnosis of other conditions. In the early 1980s, ion-selective electrodes for specific ionic species were introduced for the measurement of serum electrolytes. This new method has caused a shift of the anion gap from 12+/-4 mEq/L down 6+/-3 mEq/L. It is worthy for clinicians to understand the range of normal anion gap and the measuring methods for serum sodium and chloride in the laboratories that support their practice. While an increase in the anion gap is almost always caused by retained unmeasured anions, a decrease in the anion gap can be generated by multiple mechanisms.
Acid-Base Equilibrium*
;
Anions
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Diagnosis
;
Electrolytes
;
Ion-Selective Electrodes
;
Sodium
10.Influence of Unmeasured Anions Identified by Stewart Principle on the Length of Postoperative Hospital Stay.
Kyoung Min LEE ; Sung Ho SEO ; Seung Yun LEE ; Jun Geol LEE ; Tae Yop KIM ; Ka young RHEE
The Korean Journal of Critical Care Medicine 2005;20(2):152-158
BACKGROUND: Calculation of the base excess (BE) and the anion gap (AG) is commonly used to identify the presence and to analyze the cause of metabolic acidosis in critically ill patients. However, the calculation of BE assumes normal water content, electrolytes, and albumin, changes in these values will change the calculated BE. Calculation of the AG does not control for changes in albumin and cannot distinguish plasma concentration changes of negatively charged protein (albumin) from that of other anions. Based on Stewart's physicochemical principles, Gilfix et al developed equations to calculate the BE caused by unmeasured anions (BEua) taking into account changes in free water, chloride, albumin, and PCO2 that theoretically should reflect metabolic changes better than the less complete biochemical measurements. This study was designed to evaluate the influence of BEua and other variables on the length of postoperative hospital stay. METHODS: The data from 100 consecutive patients were collected prospectively in patients who underwent intra-abdominal operations under general anesthesia and admitted to the adult intensive care unit. All samples were routine samples taken from arterial lines postoperatively and analyzed for arterial blood gas, plasma electrolytes, inorganic phosphates and albumin concentrations. BEua was calculated from the equations developed by Gilfix et al. We also calculated AGNa, K (Na++K+-Cl--HCO3-) and AGNa (Na+-Cl--HCO3-). Correlations between the length of postoperative hospital stay and these variables were studied using linear regression analysis. RESULTS: BEua and BE were significantly correlated with the length of ICU stay (r=0.295, p<0.01 and r=0.249, p<0.05). Neither AGNa, K nor AGNa was correlated with the length of ICU stay. Significant correlation was observed between the length of postoperative hospital stay and BEua (r=0.316, p<0.01), BE (r=0.288, p<0.01), AGNa, K (r=0.284, p<0.01), and AGNa (r=0.263, p<0.05). CONCLUSIONS: In this study BEua was significantly correlated with the length of ICU stay and postoperative hospital stay compared with other variables. This finding suggests that BEua may be used as a more reliable predictor of outcome in ICU patients.
Acid-Base Equilibrium
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Acidosis
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Adult
;
Anesthesia, General
;
Anions*
;
Critical Illness
;
Electrolytes
;
Humans
;
Intensive Care Units
;
Length of Stay*
;
Linear Models
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Phosphates
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Plasma
;
Prospective Studies
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Vascular Access Devices
;
Water