1.The protecting effect on liver of Vietnam’s Linh chi mushroom (ganoderma lucidum) on rat suffering from expreimental liver function failure
Journal of Medical Research 2003;24(4):29-34
On white rats, high doses of paracetanol (2g/kg of body mass) and carbonetetrachloride (CCl4 –1.4ml/kg body mass administrated orally) increased dramatically serum transaminase AST and ALT, reduced liver capacity of cholesterol and total protein synthetizations. Granulous degeneration, lipid degeneration and necrosis focus were observed pathohistologically. Linh chi mushroom fluid extracts with the dose of 4g/kg of body mass reversed these biochemical indicators and restored nearly normally the damaged tissues. Similar results were obtained with the oral dose of 25mg Silimarin brand name preparation/kg body mass.
Agaricales
;
Reishi
;
Liver
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2.A study in the cutaneous conductivity at 12 couples of Yuan points in adults
Pharmaceutical Journal 2004;0(13):20-25
120 healthy subjects were selected and divided into two groups to study the cutaneous conductivity at 12 couples of Yuan point, group 1 including 60 subjects aged between 21 to 25 (30 males, 30 females), group 2 including 60 subjects aged between 50 to 67 (30 males, 30 females). The results: there was no difference in cutaneous conductivity at 12 couple of Yuan point of the lest and right body in both groups of ages and sexes. In female, cutaneous conductivity at 12 couple of Yuan point were diferent depending on menstrual cycle, considerably lower in the latter haft of the cycle compared to the first half of the cycle. In the same age group, cutaneous conductivity at 12 couple of Yuan point in male was lower than that in female. In the same gender group, cutaneous conductivity at 12 couple of Yuan point of the group 1 was lower that of the group 2
Administration, Cutaneous
;
Adult
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Medicine, Traditional
3.Antibiotic susceptibility of the bacterial pathogens isolated from acute respiratory patients
Journal of Preventive Medicine 2003;13(5):37-41
At the National Institute of Pediatrics, the cause of acute respiratory inflammation was studied. Most of pathogenic bacteria isolated from patients with pneumonia and bronchitis were S.pneumoniae (48%) and H.influenzae (44%). The methods using antibiotics dilution on agar to determine the minimum concentration of bacteria and PCR to determine the penicillin resistant gene sequences were used. Results showed that 58% of strains of S.pneumoniae were resistant to penicillin with a sensitivity 19%; 74% resistant to cefotaxin, sensitivity 16%. Other beta-lactamase antibiotics except ampicillin (resistance 35%, sensitivity 30%)
Anti-Bacterial Agents
;
bacteria
;
Respiratory Tract Diseases
4.Sulfur-containing compounds from Allium sativum L.
Journal of Medicinal Materials - Hanoi 2005;10(2):51-54
Garlic (Allium sativum L.) belongs to the family Liliaceae. It has been used worldwide for long time as spice and folk medicine. Sulfur-containing compounds from Allium sativum L. are especially noticed because these compounds in Allium sativum L. is significantly higher than those in other plants, and due to its pharmacological activities in sulfur-containing medications such as penicillin and sulfonamide antibiotics. From the liquid obtained by garlic cloves press, four sulfur-containing compounds were isolated. Their structures have been elucidated using MS and NMR spectroscopic methods to be ajoene (1), 2-vinyl-4H-1, 3-dithiine (2), diallyl trisulfide (3) and methyl allyl trisulfide (4)
Garlic
;
Sulfur
;
Chemistry
5.Evaluation of bioavailability of ketoprofen 200 mg long acting tablets
Pharmaceutical Journal 2003;326(6):22-24
In vitro bioavailability of ketoprofen 200mg long acting tablets by the oral were studied. Using basket dissolution tester at 120rpm. Released ketoprofen was determined by a UV – spectrophotometer at 260nm. Ketoprofen plasma levels on carefully chosen 6 healthy volunteers were within treatment which reached from 4 to 36 hours. 200mg ketoprofen LP tablets gradually released ketoprofen within 24 hours and released about 80% after 18 hours. Pharmacological parameter of ketoprofen 200mg long acting tablets have the same value compared with the results which have been published
Biological Availability
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Pharmaceutical Preparations
;
Ketoprofen
;
tablets
;
drugs
6.Studying skin temperature feature at 12 couples of Yuan point on patients with gastric - duodenal ulcer
Journal of Vietnamese Medicine 2005;0(2):55-60
A random study on skin temperature change at 12 couples of Yuan point was carried out on 120 subjects. These subjects were divided into two groups: 60 subjects with duodenal ulcer and 60 healthy subjects served as control. Results: There were difference in skin temperature of bilateral Thai xung point in both male and female with gastric-duodenal ulcer (P<0.05-0.01). Temperature of 12 couples of Yuan point in this group was higher than those in control group (P<0.05-0.001)
Peptic Ulcer
;
Skin
7.Value of the MRI through an investigation of 300 cases of cervical spinal stenosis
Journal of Vietnamese Medicine 1999;236(6):126-129
During 7/1996 - 11/1998, MEDIC - MRI department had studied 4571 patients included 985 cervical spinal cases (22%), infections (03%), degenerative diseases (51%), cervical spinal stenosis (30%), trauma (35%), tumor (06%), miscellaneous lesion (05%). Cervical spinal stenosis has been usually seen. The main etiologies of cervical spinal stenosis include cervical disc herniation, cervical spondylosis, and ossification of the posterior longitudinal ligament. It causes the severe complications such as radiculopathy and chronic myelopathy (tetraplegia, sensory disorder, and bladder dysfunction). The best knowledge of the lesion of the cervical spinal stenosis could facilitate treatment and save the patient life with hope of good motor recovery. The purpose of this study is to determine whether MRI can be used to define the nature of cervical spinal stenosis.
Constriction, Pathologic
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Magnetic Resonance Imaging
8.Study on setting up the method of quality control of iodosoja
Pharmaceutical Journal 1999;282(10):14-15
Iodosoja is an iodine containing organic compound to treat the goiter. This study aimed at setting up the method of quality control of iodosoja. The method involved the qualitative analysis (physical and chemical properties), quantitative analysis (quantification of free iodine, and total organic iodine as chemical method and spectrometry) and determination of stability (selflife) of iodosoja
Quality Control
;
Iodine
9.Study on the health care exercise of Medical Doctor NguyÔn V¨n Hëng in patients with the chronic cerebro circulation insufficiency syndrome
Journal of Practical Medicine 2001;395(3):19-21
50 patients with the chronic cerebro circulation insufficiency ages of 45-78 in the health care acupuncture department of the ViÖt Nam institute of traditional medicine participated to a study. The clinical and para-clinical changes after 45 days of training of exercise of M.D. NguyÔn V¨n Hëng were monitored. The results have shown that the exercise improved the clinical condition of the cerebro circulation insufficiency. The clinical score according to the table khadjew reduced significantly in which 62% patients with obvious remission, 35% patients with moderate remission, no patients with exacerbation of disease. The exercise improved the cerebral circulation in some biological indicators such as cerebral blood flow electroencephologram, lipemia, and respiratory function.
syndrome
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Exercise
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Cerebrovascular Disorders
10.Dosage of ketoprofen in plasma by HPLC
Pharmaceutical Journal 1998;265(5):20-22
Acetonitril was used to extract ketoprofen from plasma. The revese phase HPLC was carried out with UV detector at 253nm column Nucleosil ODS 5m (4,6*250 mm); mobile phase: MeCN: AcOH: Triethylamin: H2O (50: 0.5: 0.3: 48.7 v/v); flow rate 0.85 ml/min. Experimental results proved that the method was stable, accurate and precise
Plasma
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Ketoprofen
;
Chromatography, High Pressure Liquid