Angiolymphoid hyperplasia with eosinophilia (ALHE) and Kimura's disease were classified as same disease in the past. Since there are many different clinical and histopathological characteristics that warranted their distinction, they are classified as different disease now. Six cases of Kimura's disease in upper extremity have been reported in Korean literature but ALHE in upper extremity has not been reported yet. We experienced a case of surgically treated ALHE in the upper arm and report this case with review of literature.
Angiolymphoid Hyperplasia with Eosinophilia ; Arm ; Eosinophilia ; Upper Extremity

From March 2009 to October 2009, three pediatric patients with parotid tumor were cured. Preoperative physical examination showed regional swelling in parotid area, the surface skin was in moderate reddish purple, the border was vague, and the swelling was inactive. The patients' IgE were significantly increased. B ultrasound examination demonstrated the focus was an isoecho with ringlike dark band around, which was concluded as bull's-eye sign. Magnetic resonance imaging (MRI) examination indicated a cystic mass between the skin and parotid. Preoperative diagnosis was eosinophilichyperplastic lymphogranuloma (Kimura's disease) and the granuloma was excised by operation. Pathological examination revealed the capillary vessel hyperplasia in local tissue with a plenty of eosinophils and lymphocytes infiltrating. The disease was confirmed. Although the disease is rare, the diagnosis still could be made by preoperative physical examination, laboratory and imaging examinations.
Angiolymphoid Hyperplasia with Eosinophilia ; Humans ; Magnetic Resonance Imaging ; Male ; Parotid Gland

Angiolymphoid Hyperplasia with Eosinophilia ; pathology ; Child, Preschool ; Humans ; Male

Adult ; Angiolymphoid Hyperplasia with Eosinophilia ; Female ; Humans ; Male ; Middle Aged

Angiolymphoid Hyperplasia with Eosinophilia ; diagnosis ; pathology ; therapy ; Child ; Humans ; Male

Angiolymphoid hyperplasia with eosinophilia(ALHE) is a benign, uncommon disorder of unknown etiology, that usually appears as intradermal, subcutaneous or both, red to brown, papules and/or nodules, usually located on the head and neck of young adults and is often associated with peripheral blood eosinophilia. Extracutaneous lesions are rare. We report a 25 year-old male patient who had pruritic dark brown colored, moderately firm nodules and plaques on the left postauricular area, that histopathologically showed features of ALHE. He was treated with triamcinolone acetonide intralesional injection successfully.
Adult ; Angiolymphoid Hyperplasia with Eosinophilia* ; Eosinophilia ; Head ; Humans ; Hyperplasia ; Injections, Intralesional* ; Male ; Neck ; Triamcinolone Acetonide ; Young Adult

Kimura disease (KD) is a chronic angiolymphoid proliferative disorder of soft tissue with eosinophilia and elevated IgE levels, with predilection for head and neck in young oriental men. Renal disease is often associated with it. We describe a 16-year-old male with KD and steroid-responsive minimal change nephrotic syndrome. After surgical resection of cervical tumor and steroid therapy, complete remission of nephrotic syndrome and KD was achieved and there has been no relapse of tumor and nephrotic syndrome with normal IgE levels over 12 months.
Adolescent ; Angiolymphoid Hyperplasia with Eosinophilia* ; Eosinophilia ; Head ; Humans ; Immunoglobulin E ; Male ; Neck ; Nephrosis, Lipoid* ; Nephrotic Syndrome ; Recurrence

Kimura's disease is a rare chronic inflammatory and proliferative condition of unknown etiology. It has been thought to be a part of large spectrum of the entity known as angiolymphoid hyperplasia with eosinophilia (ALHE). However, recently the difference is emphasized between the two entities by some authors. It usually presents subcutaneous or dermal mass in the head and neck region. This condition can be mistaken for a malignant tumor. It is defined pathologically as hyperplastic lymphoid follicles, eosinophilic infiltration and vascular proliferation. Authors have experienced three cases of Kimura's disease occurring in the submandibular, axillary and inguinal regions since 1993. There were two males and one female. Two patients presented peripheral eosinophilia. All patients underwent surgical excision. Two patients were managed with oral prednisone postoperatively.
Angiolymphoid Hyperplasia with Eosinophilia ; Eosinophilia ; Eosinophils ; Female ; Head ; Humans ; Male ; Neck ; Prednisone

Epithelioid hemangioma was firstly described by Enzinger and Weiss. It belongs to a group of unusual vascular proliferation accompanying prominent eosinophilic infiltration and synonymous with angiolymphoid hyperplasia with eosinophilia(ALHE). Histopathologically, the lesion is characterized by localized, marginated and relatively symmetrical proliferation of capillaries around a medium-sized vessel with an epithelioid hyperplasia of endothelial cell and marked infiltration of inflammatory cells, eosinophils and lymphocytes. The lesion occurs usually in the dermal and subcutaneous tissue of the head and neck area. We report a case of epithelioid hemangioma occuring on the nasal tip in a 72-years-old man. Microscopically, the lesion consisted of a proliferating vessels surrounded by inflammatory infilatration predominantly composed of eosinophils and lymphocytes. But vessels were lined by conventional-appearing endothelial cells.
Angiolymphoid Hyperplasia with Eosinophilia ; Capillaries ; Endothelial Cells ; Eosinophils ; Head ; Hemangioma* ; Hyperplasia ; Lymphocytes ; Neck ; Subcutaneous Tissue

Angiolymphoid hyperplasia with eosinophilia (Kimura`s disease) is a pathologic term, given to a lesion starting usually as a papule or a cluster of papules in the skin of the head, neck and elsewhere of adults. This lesion is as extraordinary in its behavior as it is in its histology. Histologically, the characteristic features include abnormal vascular proliferations due to the growth of atypical histiocytic cells as the common dominator for all of these lesions. These lesions were apparently benign and can usually cured by surgical excision, adrenocorticosteroids and irradiation. Spontaneous remission also occurs. Herein, We report a case of this rare entity involving scrotum, reviewing the similar descriptions in western literature under various different headings.
Adult ; Angiolymphoid Hyperplasia with Eosinophilia ; Head ; Humans ; Hyperplasia* ; Neck ; Remission, Spontaneous ; Scrotum ; Skin