1.Observation on Sterility due to Chronic Protatitis and Epididymitis Treated by Self—formulated Qingjing Decoction:Report of 103 Cases
Journal of Traditional Chinese Medicine 1992;0(12):-
Studies on steritity due to abnormal seminal fluid as a result of chronic prostatitis and epididymitis in 103 cases were treated by self—formulated Qingjing De-coction with a cured rate of 77.7%,among whom 42cases were pregnant,the rate of pregnancy being 40.8% and the total effective rate,90. 3%.Clinical ob-servation revealed that the Decoction was capable of e-liminating WBC and pus cell in the semen,liquefyingthe seminal fluid,increasing the rate of motility of thesperm and decreasing the rate of deformed sperm.
2.Effect of Kidney-jing Deficiency on oxidative stress of male offspring
Jie SUN ; Anfang ZHOU ; Yanyan ZHOU ; Ting FANG
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(02):-
Objective:To investigate the effects of kidney-jing deficiency of male mice on the oxidative stress of their male offspring. Methods:Thirty 6-weeks-old Kunming male mice were divided into three groups randomly:the blank control group,the model group and the kidney-tonifying group. The model and the kidney-tonifying groups were stressesd by fear plus excessive sex to establish a kidney-jing deficiency model,and meanwhile the latter were given concentrated solution of Kidney-tonifying recipe intragastrically at the does of 0.16ml/10g. The control and the model groups were treated with physicological saline at the same dose for 21 days. Then all the male mice were mated with the healthy estrous females for 5 days. The malondialdehyde(MDA) ,superoxide dismutase(SOD) and total antioxygen capacity(T-AOC) of testicle of male offsprings were detected at 6 weeks. Results:The level of MDA in model group was higher than that in blank control group and kidney-tonifying group significantly((24.26?6.05) vs(16.54?1.47) ,(15.04?1.50) ?mol/gprot(P
3.The influence of kidney-yang deficiency on rat's gastric antrum and small intestinal mucosa tissue microstructure change
Yinjuan Lü ; Zhihua ZHANG ; Jianhong WU ; Xiang XU ; Anfang ZHOU ; Yuhui ZHANG
International Journal of Traditional Chinese Medicine 2013;(6):507-509
Objective To research the influence kidney-yang deficiency on rat' s gastric antrum and small intestinal mucosa tissue microstructure' s change.Methods The rats were cut off bilateral adrenal three-quarters to establish the model rats with deficiency of kidney-yang,which were randomly divided into a model group and a Shenfu decoction group at 4 weeks after operation.The sham operation group was the same as model group except without cutting rats bilateral adrenal and setting as a control group.The Shenfu decoction group was given suspension liquid of Shenfu decoetion by lavage,and both the control group and model group were given physiological saline of the same capacity for 4 weeks.Each rat gastric antrum and small intestinal mucosa's organization structure by conventional HE slice was observed.Results ① The sham operation group rats' gastric and intestinal mucosa were pink,shiny and elastic by macroscopic observation.Compared with the sham operation group,the gastric and intestinal mucosa of the model group became thinner,dimmer and less elastic.Compared with the model group,the gastric and intestinal mucosa of the Shenfu decoction group were a bit thicker,shinier and more elastic.② The results of the light microscope showed that:The gastric antrum and intestinal mucosa's tissue structure were normal.Compared with the sham operation group,the antrum mucosa tissue's cell gap of the model group became larger,besides the mucous glands had different degrees of alignment disorders,and a large number of vacuolar degeneration Appeared.The intestinal mucosa tissue villus edge was irregular,partial shedding of the epithelium fell offand deleted.Compared with the model group,the antrum mucosa tissue's cell gap of the Shenfu decoction group became smaller,the mucous glands cells arranged more regular,and the vacuolar degeneration had reduced.The intestinal mucosa tissue villus edge was more regular,and intestinal mucosal epithelial tissue was more complete.Conclusion The pathological changes were emerged in kidney-yang deficiency rat models.