Aneurysm, Dissecting ; therapy ; Aortic Aneurysm ; therapy ; Humans

Aortic Aneurysm, Abdominal ; therapy ; Humans

Aortic Aneurysm, Abdominal ; therapy ; Humans

Aortic Aneurysm, Abdominal ; therapy ; Humans ; Treatment Outcome

Adult ; Aged ; Aneurysm, False ; therapy ; Aortic Aneurysm ; therapy ; Embolization, Therapeutic ; Female ; Humans ; Male ; Middle Aged ; Stents

A new stent with triangular wire cross-section was proposed. The new stents were compared with traditional circular wire cross-section stent in the same porosity in order to investigate its effectiveness in treating intracranial aneurysms. Three models were established separately, including the aneurysm model with circle cross section stent, the aneurysm model with triangular cross section stent and the aneurysm model with non-stent. Then the same boundary conditions were set to contrast the resistance to flow, velocity, pressure, wall shear stress and total mesh displacement. The resistance to flow of triangular cross section stent was lower than circle cross section stent and the velocity, pressure, total mesh displacement of aneurysm model with triangular cross section stent were all higher than those of the model with circle cross section stent. Moreover, the peak value and valley value of wall shear stress in aneurysm model with triangular cross section stent were higher than those of the other. Triangular cross section stent might play a negative role to aneurysm rupturing. Thus, the therapeutic effect of stent with triangle cross section was not better than the stent with circle cross section. In the clinical application, doctors should consider the various factors, and choose the most suitable one.
Aneurysm ; therapy ; Computer Simulation ; Hemorheology ; physiology ; Humans ; Intracranial Aneurysm ; therapy ; Prosthesis Design ; Stents

OBJECTIVETo explore the causes, prevention, and management of the complications during intracranial aneurysm embolization with controllable coils (mechanical detachable spiral, MDS; and Guglielmi detachable coil, GDC).

METHODSRetrospective review of 120 cases with 125 intracranial aneurysms embolized with controllable coils from March 1995 to July 1999 was conducted. The 20 accidents (in 18 cases) including aneurysm rupture, over-embolization, protrusion of coil end into the parent artery, and thrombosis of the parent artery were analyzed.

RESULTSAmong the 20 accidents, there were 6 aneurysm ruptures, 6 over-embolizations (in 5 cases), 6 coil protrusions, and 2 thromboses (one was secondary to coil protrusion). The embolization-related mortality was 3.33% (4/120), the permanent neurological deficit was 1.67% (2/120), and the transitory neurological deficit was 3.33% (4/120). The occurrence and outcome of the complications were related to the embolizing technique, the pattern of aneurysm and its parent artery, the imperfection of embolic materials, and the observation and management during embolization.

CONCLUSIONSkilled embolizing technique, better understanding of the angio-anatomy of an aneurysm and its parent artery, correct judgement and management during embolization, and improvement of embolic materials are beneficial to the reduction of complications and to the melioration of the outcome of complications.

Aneurysm, Ruptured ; etiology ; Embolization, Therapeutic ; adverse effects ; instrumentation ; Humans ; Intracranial Aneurysm ; therapy ; Retrospective Studies ; Thrombosis ; etiology

Aneurysm, False/therapy* ; Cardiac Catheterization ; Heart Aneurysm ; Heart Ventricles/surgery* ; Humans

BACKGROUNDStent placement has been widely used to assist coiling in cerebral aneurysm treatments. The present study aimed to investigate the hemodynamic effects of stenting on wide-necked intracranial aneurysms.

METHODSThree idealized plexiglass aneurismal models with different geometries before and after stenting were created, and their three-dimensional computational models were constructed. Flow dynamics in stented and unstented aneurismal models were studied using in vitro flow visualization and computational fluid dynamics (CFD) simulations. In addition, effects of stenting on flow dynamics in a patient-specific aneurysm model were also analyzed by CFD.

RESULTSThe results of flow visualization were consistent with those obtained with CFD simulations. Stent deployment reduced vortex inside the aneurysm and its impact on the aneurysm sac, and decreased wall shear stress on the sac. Different aneurysm geometries dictated fundamentally different hemodynamic patterns and outcomes of stenting.

CONCLUSIONSStenting across the neck of aneurysms improves local blood flow profiles. This may facilitate thrombus formation in aneurysms and decrease the chance of recanalization.

Embolization, Therapeutic ; methods ; Humans ; Hydrodynamics ; Intracranial Aneurysm ; therapy ; Stents

An electrolytically-detachable microcoil is introduced here in the paper. The testing results indicate that, the microcoils have stable mechanical properties, clear radiographic images and fine insulation performance. Their detaching time varies from 30s to 200s when voltage changes from 2V to 5V.
Embolization, Therapeutic ; instrumentation ; Equipment Design ; Intracranial Aneurysm ; therapy