7.Analysis of factors related to acute renal failure post deep hypothermia circulatory arrest surgery of type A aorta dissection surgery.
Fei LI ; Nan LIU ; Ping DONG ; Xiao-tong HOU
Chinese Journal of Surgery 2013;51(12):1094-1098
OBJECTIVESTo analyze risk factors associated to acute renal failure (ARF) post deep hypothermia circulatory arrest (DHCA) surgery of type A aorta dissection patients, researching correlations to hospital mortality rate.
METHODSThere were 273 samples of type A aorta dissection patients collected between September 2011 and May 2013 , all of which had surgery done under DHCA. Categorize the samples into two groups based on whether postoperative ARF happened: non-ARF group(n = 163) and ARF group(n = 110). Conducted regression analysis correlations between postoperative ARF and mortality and one or more risk factors of gender, age, history of illness, type of aorta dissection, heart functional class, pre- and post-operative serum creatinine (sCr), DHCA time, blood loss and blood transfusion volume, postoperative complications, etc.
RESULTSAmong the 110 samples of ARF group (40.3%), 21 (7.7%) conducted continuous renal replacement therapy (CRRT). Among 16 (5.9%) died in hospital, 3 (1.8%) died with functional renal, 13 (11.8%) died with ARF. Single factor analysis: male (χ(2) = 6.075, P = 0.014), preoperative sCr (t = 2.955, P = 0.004), dissection extended to renal artery(χ(2) = 5.103, P = 0.024), cardiopulmonary by-pass (CBP) time (t = 2.435, P = 0.017), DHCA time (t = 2.215, P = 0.031), average lower limb artery blood pressure during CBP (t = -2.832, P = 0.007), during surgery and 24 h postoperative blood loss (t = 2.157, P = 0.034) and blood transfusion (t = 2.426, P = 0.018), postoperative acute respiratory dysfunction (χ(2) = 36.307, P = 0.000), postoperative endotracheal reintubation (χ(2) = 9.167, P = 0.002), postoperative low blood pressure (χ(2) = 10.202, P = 0.001), postoperative temporary neurological deficits (χ(2) = 7.512, P = 0.006), postoperative infection (χ(2) = 11.088, P = 0.001) were the risk factors for ARF. The logistic regression analysis revealed that preoperative sCr (P = 0.023) and acute respiratory dysfunction (P = 0.011) were independent determinants of ARF; preoperative ARF (P = 0.022), CRRT (P = 0.003) and permanent neurological deficits were independent determinants for hospital mortality.
CONCLUSIONSARF is a common complication of post Type A aorta dissection surgery under DHCA, and is the risk factor of hospital mortality. It is important to enhance peri-operative protection of the renal function.
Acute Kidney Injury ; etiology ; Adult ; Aged ; Aneurysm, Dissecting ; surgery ; Aortic Aneurysm ; surgery ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications ; etiology
8.Two cases of acute aortic dissection following preeclampsia in non-Marfan patients.
Jian HUANG ; Hui LIU ; Yi-Ling DING
Chinese Medical Journal 2012;125(11):2073-2075
Aortic dissection accompanying with preeclampsia during pregnancy can be lethal to both the mother and the fetus and carries a high mortality. Of the 2 preeclampsia patients with aortic dissection, one was Type B aortic dissection, occurring in postpartum period. The patient was treated medically and underwent catheter-based stent-graft treatment with fenestration technique. Another patient was Type A acute dissection, occurring in the third trimester. This patient was undiagnosed and both died. Although extremely rare, aortic dissection might be a possibility in preeclampsia pregnant women, the differential diagnosis of chest and/or epigastric pain in preeclampia patient should be thoroughly investigated and treated.
Adult
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Aneurysm, Dissecting
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diagnosis
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etiology
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Female
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Humans
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Pre-Eclampsia
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physiopathology
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Pregnancy
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Pregnancy Complications, Cardiovascular
10.Spontaneous rupture of the lateral thoracic artery in patients with liver cirrhosis.
Tae Hee LEE ; Yong Sung PARK ; Dong Jin CHUNG ; Ji Hyung KIM ; Sun Moon KIM ; Euyi Hyeog IM ; Kyu Chan HUH
The Korean Journal of Internal Medicine 2008;23(3):152-155
Bleeding in patients with liver cirrhosis is primarily caused by gastroesophageal varix in association with extensive collateral circulation, portal hypertensive gastropathy, a Mallory-Weiss tear and peptic ulcer disease. The spontaneous rupture of an artery, as a result of coagulopathy, is extremely rare in patients with liver cirrhosis; however, we recently observed a case of a spontaneous rupture of the lateral thoracic artery in a 47 year-old male patient with alcoholic liver cirrhosis. The patient expired despite repeated transcatheter arterial embolization of the lateral thoracic artery and best supportive care. This is, to our knowledge, the first documented case of the spontaneous rupture of the lateral thoracic artery in a patient with liver cirrhosis.
Aneurysm, Dissecting/*etiology
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Fatal Outcome
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Humans
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Liver Cirrhosis/*complications
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Male
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Middle Aged
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Rupture, Spontaneous/*etiology
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Thoracic Arteries/*pathology
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Time Factors