Manuscripts submitted to journals should be understandable even to those who are not experts in a particular field. Moreover, they should use publicly available materials and the results should be verifiable and reproducible. Readers and reviewers will want to check the strengths and weaknesses of the research study design, and ways to make this determination should be clear through proper analysis methods. Studies should be described in detail so as to help readers understand the results. Statistical analysis is one of the key methods by which to do this. The inappropriate application of statistical methods could be misleading to readers and clinicians. While many researchers describe their general research methods in detail, statistical methods tend to be described briefly, with certain omissions or errors or other incorrect aspects. For instance, researchers should describe whether the median or mean was used, whether parametric or nonparametric tests were used, whether the data meet the normality test, whether confounding factors were corrected, and whether stratification or matching methods were used. Statistical analysis regardless of the program should be reported correctly. The results may be less reliable if the statistical assumptions before applying the statistical method are not met. These common errors in statistical methods originate from the researcher's lack of knowledge of statistics and/or from the lack of any statistical consultation. The aim of this work is to help researchers know what is important statistically and how to present it in papers.
Anesthesia* ; Methods

When a Jehovah's Witness patient rejects transfusion because of his religious doctrine, the anesthesiologist is required to make an important decision. Each doctor must approach his patient respecting the patient's wishes as much as possible, while still taking into account his own ethical criteria, moral judgement of the patient, and knowledge of medicine. This writer briefly examined the basis of the religious doctrine of a Jehovah's Witness advocate and consulted a scholar of the criminal court about the legal interpretation of the doctor's behavior in our present situation where no detailed judicial precedent was available. I summarized medical solution here by referring to foreign records of medical studies and case reports in the hopes that it may aid in anesthetic management of Jehovah's Witness patients.
Anesthesia/*methods ; *Christianity ; Humans

At the present time, a kind of monitoring technology assuring highly effectual anesthesia is urgently required in the clinical practice. Electroencephalogram (EEG) assumes a dominant position in the current research of the depth detection of anesthesia. In this paper, the monitoring technique of the depth detection of anesthesia by bispectral index (BIS) is systematically showed. The bispectral index is a compound parameter which is composed of time domain, frequency domain, and high order spectral subparameters of the electroencephalograph. This nonlinear compound calculation method is worth research and is of great significance to the development of a new monitor of closed-loop control of anesthesia.
Anesthesia ; methods ; Electroencephalography ; methods ; Monitoring, Intraoperative ; methods

BACKGROUND: This study undertook to compare the effect-site concentration of remifentanil for prevention of hemodynamic responses to endotracheal intubation, employing the single-lumen tracheal tube and the double-lumen bronchial tube during total intravenous anesthesia. METHODS: Based on the nature of the surgery, 38 patients undergoing general anesthesia were assigned either to the single-lumen tube group or the double-lumen tube group. Anesthesia was induced by a target controlled infusion of propofol, with an effect-site concentration of 4 µg/ml. Remifentanil was then administered to the first patient in each group, with an effect-site concentration of 3.5 ng/ml. Subsequent concentration of remifentanil was determined by hemodynamic responses of the previous patient to intubation, based on the up-and-down method. RESULTS: The effect-site concentrations of remifentanil for prevention of hemodynamic responses to endotracheal intubation in 50% of patients (EC₅₀) were 2.8 ng/ml (95% CI, 2.0–3.7 ng/ml) in the single-lumen tube group, and 2.9 ng/ml (95% CI, 2.5–3.2 ng/ml) in the double-lumen tube group. No significant difference was observed between the two groups. CONCLUSIONS: The effect-site concentration of remifentanil for prevention of hemodynamic responses to endotracheal intubation did not differ during total intravenous anesthesia, using either the single-lumen tracheal tube or the double-lumen bronchial tube.
Anesthesia ; Anesthesia, Endotracheal ; Anesthesia, General ; Anesthesia, Intravenous ; Hemodynamics* ; Humans ; Intubation* ; Intubation, Intratracheal ; Methods ; Propofol

Maternal and fetal effects of anesthesia for 423 cesarian section, performed during the past three and quarter years period in this hospital, have been evaluated. It is emphasized that the selection of anesthetic agent and method should depend upon the physical status of the patients and the ability of both obstetrician and anesthesiologists. Author results were as follows: 1. The incidence of c-section was 13.9% of total deliveries. 2. More than about three fourths of total cases were emergency cases. 3. Almost all cases were operated under general anesthesia. 4. The good physical states of patients resulted in better Apgar score of infants. 5. The shorter the interval from induction of anesthesia to delivery, the better was the Apgar score of infants.
Anesthesia ; Anesthesia, General ; Apgar Score ; Emergencies ; Humans ; Incidence ; Infant ; Methods

Local anesthesia is administered to reduce pain during dental treatments, but may itself cause pain and contribute to increased dental fear. Computer-controlled local anesthetic delivery (CCLAD) is one the method to reduce patient pain during local anesthesia; it is a device that slowly administers anesthetics by using a computerized device to control the injection speed. This literature review aims to provide an objective assessment of the usefulness of CCLAD for controlling pain by reviewing papers published to date that have used CCLAD.
Anesthesia* ; Anesthesia, Local ; Anesthetics ; Dental Anxiety ; Humans ; Methods

Local anesthesia is administered to reduce pain during dental treatments, but may itself cause pain and contribute to increased dental fear. Computer-controlled local anesthetic delivery (CCLAD) is one the method to reduce patient pain during local anesthesia; it is a device that slowly administers anesthetics by using a computerized device to control the injection speed. This literature review aims to provide an objective assessment of the usefulness of CCLAD for controlling pain by reviewing papers published to date that have used CCLAD.
Anesthesia* ; Anesthesia, Local ; Anesthetics ; Dental Anxiety ; Humans ; Methods

The inferior alveolar nerve block is the most common method of local anesthesia for intraoral surgery at the posterior mandibular region. However, unexpected complications may occur when administering the local anesthesia. One of these uncommon complications is the fracture of the needle. If the injection needle is broken during the surgery, it should be removed immediately. However, this is one of the most difficult procedures. In this report, we present two cases of needle fracture during the procedure, and its successful removal under general/local anesthesia administration.
Anesthesia ; Anesthesia, Local ; Mandibular Nerve* ; Methods ; Needles* ; Nerve Block

Adult ; Anesthesia, General ; methods ; Anesthesia, Intravenous ; methods ; Cesarean Section ; methods ; Female ; Humans ; Muscular Atrophy, Spinal ; Pregnancy

PURPOSE: The aim of this study is to evaluate the effect of dexmedetomidine on corrected QT (QTc) and Tp-e intervals in patients undergoing spinal anesthesia. MATERIALS AND METHODS: We studied 50 patients who were scheduled to undergo spinal anesthesia before orthopedic surgeries. Patients were allocated to receive either an infusion of dexmedetomidine or normal saline after spinal anesthesia. RESULTS: QTc intervals were significantly prolonged after spinal anesthesia, and the prolonged QTc interval returned to baseline values 10 minutes after either normal saline or dexmedetomidine administration in both groups. The QTc interval values after dexmedetomidine administration were significantly shorter compared to the QTc interval values just before dexmedetomidine administration. CONCLUSION: Dexmedetomidine could promote the return of a prolonged QTc interval induced by spinal anesthesia and might be helpful in patients who have a prolonged QTc interval.
Anesthesia, Spinal* ; Dexmedetomidine* ; Electrocardiography ; Humans ; Methods ; Orthopedics