Objective: To assess the quality of life (QoL) and recurrenceof disease in patients with eosinophilic (ECRSwNP) andnon-eosinophilic chronic rhinosinusitis with nasal polyposis(non-ECRSwNP) post endoscopic sinus surgery (ESS).Methodology: A cross-sectional comparative study wascarried out in the Otorhinolaryngology – HNS Department,Universiti Kebangsaan Malaysia Medical Center (UKMMC).Subjective assessments of nasal symptoms and quality oflife (QoL) using SNOT-22 and Visual Analogue Scale (VAS)and objective endoscopic assessment was undertakenusing a modified Hadley endoscopic examination.Results: There was no significant statistical difference in thequality of life between the ECRSwNP and non-ECRSwNPgroups as evidenced by the SNOT-22 score and the VAScomparison (p>0.05). However, there was a significantdifference in terms of recurrence of disease with thepresence of nasal polyps on endoscopic examination. (p =0.016)Conclusion: In conclusion, we found that there is nosignificant difference in QoL between ECRSwNP and nonECRSwNP.There is higher frequency of recurrence of nasalpolyps amongst ECRSwNP.