Disease outbreaks pose serious threats to humans, as highlighted by the recent pandemic, underscoring the need for an institutionalized multi-sectoral approach like One Health, encompassing human, animal, and environmental health. One Health has demonstrated efficacy in addressing emerging issues such as antimicrobial resistance and zoonotic disease spillover. While integrating the human-animal sector has yielded positive outcomes, the majority of zoonotic spillovers originate from wildlife, emphasizing the crucial role of environmental surveillance within global One Health systems. Additionally, climate change intensifies the frequency and emergence of infectious diseases and spillover events. Tackling the complexity and interconnectedness of health challenges necessitates integrated solutions that incorporate broader structural factors, aiding in the prevention, detection, and mitigation of disease outbreaks. Embracing One Health through multi-sectoral preparedness can effectively confront the escalating threats of pandemics and other emerging diseases.

Disease outbreaks pose serious threats to humans, as highlighted by the recent pandemic, underscoring the need for an institutionalized multi-sectoral approach like One Health, encompassing human, animal, and environmental health. One Health has demonstrated efficacy in addressing emerging issues such as antimicrobial resistance and zoonotic disease spillover. While integrating the human-animal sector has yielded positive outcomes, the majority of zoonotic spillovers originate from wildlife, emphasizing the crucial role of environmental surveillance within global One Health systems. Additionally, climate change intensifies the frequency and emergence of infectious diseases and spillover events. Tackling the complexity and interconnectedness of health challenges necessitates integrated solutions that incorporate broader structural factors, aiding in the prevention, detection, and mitigation of disease outbreaks. Embracing One Health through multi-sectoral preparedness can effectively confront the escalating threats of pandemics and other emerging diseases.

Disease outbreaks pose serious threats to humans, as highlighted by the recent pandemic, underscoring the need for an institutionalized multi-sectoral approach like One Health, encompassing human, animal, and environmental health. One Health has demonstrated efficacy in addressing emerging issues such as antimicrobial resistance and zoonotic disease spillover. While integrating the human-animal sector has yielded positive outcomes, the majority of zoonotic spillovers originate from wildlife, emphasizing the crucial role of environmental surveillance within global One Health systems. Additionally, climate change intensifies the frequency and emergence of infectious diseases and spillover events. Tackling the complexity and interconnectedness of health challenges necessitates integrated solutions that incorporate broader structural factors, aiding in the prevention, detection, and mitigation of disease outbreaks. Embracing One Health through multi-sectoral preparedness can effectively confront the escalating threats of pandemics and other emerging diseases.

Disease outbreaks pose serious threats to humans, as highlighted by the recent pandemic, underscoring the need for an institutionalized multi-sectoral approach like One Health, encompassing human, animal, and environmental health. One Health has demonstrated efficacy in addressing emerging issues such as antimicrobial resistance and zoonotic disease spillover. While integrating the human-animal sector has yielded positive outcomes, the majority of zoonotic spillovers originate from wildlife, emphasizing the crucial role of environmental surveillance within global One Health systems. Additionally, climate change intensifies the frequency and emergence of infectious diseases and spillover events. Tackling the complexity and interconnectedness of health challenges necessitates integrated solutions that incorporate broader structural factors, aiding in the prevention, detection, and mitigation of disease outbreaks. Embracing One Health through multi-sectoral preparedness can effectively confront the escalating threats of pandemics and other emerging diseases.

Disease outbreaks pose serious threats to humans, as highlighted by the recent pandemic, underscoring the need for an institutionalized multi-sectoral approach like One Health, encompassing human, animal, and environmental health. One Health has demonstrated efficacy in addressing emerging issues such as antimicrobial resistance and zoonotic disease spillover. While integrating the human-animal sector has yielded positive outcomes, the majority of zoonotic spillovers originate from wildlife, emphasizing the crucial role of environmental surveillance within global One Health systems. Additionally, climate change intensifies the frequency and emergence of infectious diseases and spillover events. Tackling the complexity and interconnectedness of health challenges necessitates integrated solutions that incorporate broader structural factors, aiding in the prevention, detection, and mitigation of disease outbreaks. Embracing One Health through multi-sectoral preparedness can effectively confront the escalating threats of pandemics and other emerging diseases.

Ischiofemoral impingement syndrome is a rare clinical entity characterized by chronic groin, buttock or hip pain associated with radiographic evidence of narrowing of the space between the lesser femoral trochanter and the ischial tuberosity. Introduction of magnetic resonance imaging to the clinical practice as well as the establishment of the radiological definition of the abnormal ischiofemoral distance has led to an increasing interest in this condition. Ischiofemoral impingement syndrome is a poorly understood disorder of chronic pain, especially regarding its treatment. The authors present two cases of primary ischiofemoral impingement syndrome successfully treated with a minimally invasive surgical technique. With this endoscopic technique, it was possible to resect the lesser trochanter and restore the ischiofemoral space. Immediate clinical and functional improvement was reported by both patients.
Arthroscopy ; Buttocks ; Chronic Pain ; Femur* ; Groin ; Hip ; Humans ; Magnetic Resonance Imaging

Background: Untreated osteonecrosis of the femoral head ultimately leads to secondary coxarthrosis. The aim of this study was to determinate if the core decompression of the femoral head combined with implantation of autologous bone marrow concentrate with tricalcium phosphate could be used to prevent radiographic progression of early stage osteonecrosis of the hip. We also sought to determine whether this treatment improved clinical outcomes and reduced the need for total hip arthroplasty. Methods: Eighteen hips were included in the present study. All of them underwent core decompression of the femoral head combined with implantation of autologous bone marrow concentrate with tricalcium phosphate between 2007 and 2012. The cell concentrate was obtained from the posterior iliac crest and processed and implanted during the same surgical procedure. Patient demographic data, clinical data including modified Harris hip score, and radiological data were collected preoperatively, postoperatively, and during the follow-up period. Also, survival endpoints were analyzed: time of femoral head collapse and need for total hip arthroplasty. Results: The mean age of patients was 37.8 years (standard deviation [SD], 9.31 years). The mean follow-up was 68.9 months (SD, 15.0 months). In most cases (70.6%), the etiology of the osteonecrosis of the femoral head was corticosteroid use; in the remaining cases, secondary to alcohol use. Core decompression of the femoral head combined with implantation of autologous bone marrow concentrate with tricalcium phosphate did not prevent progression to collapse (< 80% at 5 years) although modified Harris hip scores improved. Overall median survival with the total hip arthroplasty as endpoint was 23 months (95% confidence interval [CI], 14.9 to 31.1 months). Overall median survival time with any degree of collapse as endpoint was 7 months (95% CI, 2.0 to 12.0 months). Conclusions The results obtained in this study suggest that core decompression combined with implantation of autologous bone marrow concentrate and tricalcium phosphate will not prevent radiographic progression of early stage osteonecrosis of the hip. These finding also suggest that the absence of indications for hip replacement alone is not an indicator of good response to the treatment, and it is important to note the radiological results.