Meningiomas and pilocytic astrocytomas are benign intracranial tumors. Pilocytic astrocytomas arises frequently at the posterior fossa in childhood. Meningiomas have several image findings, such as a dural tail sign, bony erosion, and sunburst appearance on angiography. However, pilocytic astrocytomas with these findings have been rarely reported. In this report, we describe a mass with typical image findings of a meningioma, but diagnosed as a supratentorial pilocytic astrocytoma with early anaplastic transformation.
Anaplasia ; Angiography ; Astrocytoma* ; Meningioma* ; Radiography ; Tail

Malignant fibrous histiocytama is currently defined as a malignant primary bone tumor, and that may contain fibromatoua, xanthomatous, or histiocytic elementa, varing widely in the degree of anaplasia that is present. The principal lesions to be considered in the differential diagnoais of malignant fibrous histiocytoma are osteogenic sarcoma and fibrosarcoma. Malignant fibrous histiocytoma is more sensitive to chemotherapeutic ageata than are osteosarcama and fibrosarcama. In this paper 2 cases sre reported, including the one in which the tumor arose in a midahaft of the femur and the other one arosein the upper metaphyseal portion of the tibla.
Anaplasia ; Femur ; Fibrosarcoma ; Histiocytoma, Malignant Fibrous ; Osteosarcoma

The authors present 2 cases of malignant pituitary adenoma. One case has remote metastases to the right frontal lobe, and the other case has invasion into the adjacent temporal lobe and malignant features histologically. Malignant pituitary adenoma constitute less than 1% of the large reported series of pituitary adenoma, which defined as (1) it burst its capsule to invade the adjacent nervous structures or bone, (2) it shows malignant features histologically, such as frequent mitoses, anaplasia with hyperchromatic pleomorphic cells, loss of alveolar arrangement, and (3) presence of distant metastases.
Anaplasia ; Frontal Lobe ; Mitosis ; Neoplasm Metastasis ; Pituitary Neoplasms* ; Temporal Lobe

We report one case of adenoma malignum of the cervix. Adenoma malignum is an extremely well-differentiated form of adenocarcinoma in which the branching glandular pattern strongly simulates that of the normal endocervical glands. This term has been used to describe a very well-differentiated adenocarcinoma characterized histologically by distorted and architecturally irregular endocervical glands which penetrate deeply into the wall of the cervix, but with minimal and focal evidence of glandular cell stratification, anaplasia, or mitotic activity. Despite this innocuous histologic appearance, these tumors have classically been thought to be clinically highly malignant, with an almost invariably rapid lethal outcome. The diagnosis of minimal deviation adenocarcinoma (adenoma malignum) of the endocervix may be difficult. The diagnosis was adenocarcinoma on the Pap Smear treatment has been hysterectomy.
Adenocarcinoma ; Adenoma* ; Anaplasia ; Cervix Uteri* ; Diagnosis ; Female ; Hysterectomy

A histologic analysis of 10 cases of Wilms` tumor in the department of Urology, Chosun University Hospital during 11 years periods from January, l975 to December, l985 has been carried out. A classification based on the tumor differentiation and degree of tubular formation are described. A comparison of the histologic findings with the survival was undertaken and it was found that the histologic classification was significantly correlated with survivals. The results were as follows : I. Low grade tumors(grade I) with predominance of differentiated tubules were associated with a better cure rate than high grade tumors(grade IH) composed mainly of undifferentiated spindle elements : 2 year or more survival rate was lOOf6 for grade I but O% for grade III. 2. Cure rate was lower for the low degree of tubular formation than for the high degree of tubular formation : 2-year cure rates were O%, O%, 33.3%, lOO% for group O, +,++ and +++ respectively. 3. 6 patients with the focal or diffuse anaplasia and sarcomatous stroma had a bad prognosis. giving a survival rate of 0%.
Anaplasia ; Classification ; Humans ; Prognosis* ; Retrospective Studies* ; Survival Rate ; Urology

Records of 15 patients of primary ureteral tumor which were managed in Seoul National University Hospital during 13.5 years period from January 1971 to June 1983. 1. Primary ureteral tumor comprised of 2% of all urothelial tumors and the ratio of bladder:pelvis:ureter was 40:2:1. 2. There were 11men and 4 women (ratio of 3:1) with a mean age of 62.7 years. 3. The most frequent site of ureteral tumor was the lower one third of the ureter (53%). 4. Most frequent presentation was gross hematuria. usually intermittent and painless (100%). 5. Non-visualization of the kidney was the most prevalent finding (73%) on excretory urogram. Retrograde pyelogram was necessary in 11 patients whose findings of IVP was insufficient for diagnosis, and these procedures provided definite diagnosis in 9 of 11 patients. 6. Urine cytology was positive in 4 of 13 patients. 7. Cystoscopy was performed in all patients and which revealed concomitant bladder tumor in3 patients and tumor in ureteral orifice in 2 patients. 8. There was close correlation between the grade of cellular anaplasia and the degree of invasion. 9. There were 3 recurrences (50%) in the ureteral stump in 6 patients treated by nephrectomy and partial ureterectomy.
Anaplasia ; Cystoscopy ; Diagnosis ; Female ; Hematuria ; Humans ; Kidney ; Nephrectomy ; Recurrence ; Seoul ; Ureter* ; Urinary Bladder Neoplasms

Epithelioma cuniculatum or plantar verrucous carcinoma shows a great tendency toward deep penetrating growth, resulting in numerous crypts filled with horny material and pus. We herein described a 44 year-old female who showed a warty, relatively round, brown to yellow colored protruding mass with many crypts filled with pus-like exudates, measuring 2.3 X 2.5 X 1.5 cm in size, and of 5 years duration. The biopsy specimen taken from the tumor mass revealed a deeply penetrating, well-differentiated squarnous cell carcinoma without nuclear anaplasia and individual cell keratinization.
Adult ; Anaplasia ; Biopsy ; Carcinoma* ; Carcinoma, Verrucous ; Exudates and Transudates ; Female ; Humans ; Suppuration

No abstract available.
Anaphase-Promoting Complex-Cyclosome ; Neoplasms ; Cell Nucleus ; Colorectal Neoplasms ; Anaplasia ; Aneuploidy

It is often assumed that a parenchymal brain lesion which shows no contrast enhancement on magnetic resonance imaging(MRI) is a"low-grade tumor". We investigated a series of 20 patients with nonenhancing cerebral gliomas ; all underwent stereotactic biopsy or open resection, and histological diagnoses were astrocytoma(n=7), anaplastic astrocytoma(n=7), oligodendroglioma(n=5), and ganglioglioma(n=1). Before surgery, 11 patients underwent [18F] fluorodeoxyglucose positron emission tomography(FDG-PET), and this showed hypermetabolic features in two of four patients with anaplastic astrocytomas and in one of seven with astrocytomas or oligodendrogliomas. Among 17 patients, the mean Ki-67 labeling index was 4.4+/-4.3(range : 0.1-16.7), and the standard error was 1.04. These results indicate that in cerebral gliomas, the enhancing pattern seen on MRI cannot predict the degree of malignancy, and we suggest that even if imaging is consistent with "low-grade glioma", histological verification and close follow-up of clinical course are both important.
Anaplasia ; Astrocytoma ; Biopsy ; Brain ; Diagnosis ; Electrons ; Follow-Up Studies ; Glioma* ; Humans ; Magnetic Resonance Imaging ; Oligodendroglioma

anaplasia or mitosis of the tumor cells. Sometimes, the exact diagnosis of osteosarcoma is difficult especially in low grade osteosarcoma, even if clinical or radiographical findings suggest to osteosarcoma. So suspcious to malignant bone tumor in clinical or radiological findings, biopsy should be taked from deep portion and multiple area, and sharing the patient history and radiographs with pathologist will assist in the development of the diagnosis. We report a case of low grade osteosarcoma on the mandible initially difficulty in accurate diagnosis. The patient visited our hospital for routine dental treatment but radiographic findings displayed ill-defined radiolucency with osteoid formation on the mandible. Final diagnosis was difficulty in initial biopsy but subsequent biopsy taked from deep portion presented infiltrative growth and mitosis of the tumor cell in some area with small osteoid bone foramtion, so we could reach final diagnosis as low grade sarcoma. We treated this patient with bloc resection of the mandible and immediate reconstruction with iliac corticocancellous block.]]>
Anaplasia ; Biopsy ; Chondrocytes ; Diagnosis ; Fibroblasts ; Head ; Humans ; Jaw ; Mandible ; Mitosis ; Neck ; Osteoblasts ; Osteosarcoma ; Sarcoma ; Survival Rate