1.Advances in researches on drug anaphylaxis of the penis.
National Journal of Andrology 2005;11(6):403-405
Anaphylaxis is one of the most common and harmful of all adverse effects of drugs. It has no direct relation to the toxicity and dosage of drugs, but belongs to the pathologic immune reaction, directly threatening patients' lives. At present, many important advances and breakthroughs have been achieved in the researches on drug anaphylaxis of the penis, but many researchers have gone hardly any further than reporting the symptoms and treatments of a few individual cases, but very few specific substantial researches on penis drug anaphylaxis.
Allergens
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adverse effects
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Anaphylaxis
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Drug Hypersensitivity
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etiology
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therapy
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Humans
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Male
;
Penile Diseases
;
chemically induced
;
therapy
2.Kounis syndrome: allergic acute coronary syndrome.
Min XU ; Xue-si WU ; Teng-yong JIANG ; Ji-qiang HE
Chinese Medical Journal 2013;126(13):2591-2592
4.Anaphylactic shock in a boy after taking oral ofloxacin.
Yan-ming GU ; Xiao-yi CHEN ; Yong-qing WANG
Chinese Journal of Pediatrics 2005;43(8):607-607
Administration, Oral
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Anaphylaxis
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chemically induced
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physiopathology
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therapy
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Anti-Bacterial Agents
;
administration & dosage
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adverse effects
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Blood Pressure
;
drug effects
;
Child
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Diarrhea
;
drug therapy
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Humans
;
Male
;
Ofloxacin
;
administration & dosage
;
adverse effects
;
Treatment Outcome
5.Anaphylaxis Caused by Benzalkonium in a Nebulizer Solution.
Journal of Korean Medical Science 2004;19(2):289-290
Benzalkonium chloride (BAC) is commonly used as a bactericidal preservative in nebulizer solutions, and can cause paradoxical onchoconstriction following nebulizing therapy in some asthmatics. We describe a case of anaphylactic shock in a 23-yr-old asthmatic woman following an intradermal skin test with a salbutamol solution containing BAC. Since she complained of cough and dyspnea after inhalation therapy with a nebulizer solution, we conducted an intradermal skin test using the same solution, which contained BAC. About 10 min later, the patient reported dizziness, palpitations, and dyspnea. On examination, tachycardia, tachypnea, and hypotension were found. She was resuscitated with a subcutaneous injection of epinephrine and an infusion of saline. One month later, we conducted a bronchial provocation test with BAC, and she showed a positive response.
Adult
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Anaphylaxis/*chemically induced
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Anti-Asthmatic Agents/administration & dosage
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Anti-Infective Agents, Local/*adverse effects
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Asthma/*drug therapy
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Benzalkonium Compounds/*adverse effects
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Female
;
Human
;
Nebulizers and Vaporizers
;
Support, Non-U.S. Gov't
6.A Case of Anaphylaxis to Chlorhexidine during Digital Rectal Examination.
Yun Jeong BAE ; Chan Sun PARK ; Jae Keun LEE ; Eunheui JEONG ; Tae Bum KIM ; You Sook CHO ; Hee Bom MOON
Journal of Korean Medical Science 2008;23(3):526-528
Chlorhexidine is widely used as an antiseptic and disinfectant in medical and nonmedical environments. Although the sensitization rate seems to be low, its ubiquitous use raises the possibility of sensitization in many patients and medical care workers. We describe a patient with anaphylaxis during digital rectal examination with chlorhexidine jelly. Urticaria, angioedema, dyspnea, and hypotension developed within a few minutes of the rectal examination. The patient fully recovered after treatment with epinephrine and corticosteroids. Skin tests for chlorhexidine were undertaken 5 weeks later, showing positive prick and intradermal skin tests. Within 30 min of the skin test, the patient complained of febrile sensation, chest tightness, angioedema, and urticaria on the face and trunk. An enzyme allergosorbent test for latex was negative. We present this case to alert clinicians about hypersensitivity to chlorhexidine that could potentially be life-threatening. We suggest that chlorhexidine should be recognized as a causative agent of anaphylaxis during procedural interventions.
Administration, Topical
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Adrenal Cortex Hormones/administration & dosage
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Anaphylaxis/*chemically induced/drug therapy
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Anti-Infective Agents, Local/administration & dosage/*adverse effects
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Chlorhexidine/administration & dosage/*adverse effects
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*Digital Rectal Examination
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Epinephrine/administration & dosage
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Humans
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Male
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Middle Aged
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Sympathomimetics/administration & dosage
7.Suspected Anaphylactic Reaction Associated with Microemulsion Propofol during Anesthesia Induction.
Se Jin LEE ; Soon Im KIM ; Bo Il JUNG ; Su Myung LEE ; Mun Gyu KIM ; Sun Young PARK ; Sang Ho KIM ; Si Young OK
Journal of Korean Medical Science 2012;27(7):827-829
Although rare, intraoperative anaphylaxis can lead to significant morbidity and mortality. Aquafol(R) (Daewon Pharmaceutical Co. Ltd., Seoul, Korea), a microemulsion propofol, was developed to eliminate lipid solvent-related adverse events, and was used in clinical anesthesia since 2009 with little data about severe side effects such as anaphylaxis. A healthy 16-yr-old male patient who had past medical history with two previous operations of no complications developed cardiovascular shock with generalized erythema following administration of microemulsion propofol during anesthesia induction. Intravenous injection of epinephrine and steroid rescued him. He remained in a stable state without any problems postoperatively and was discharged. Clinicians should consider this rare but serious complication during induction of anesthesia with propofol.
Adolescent
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Anaphylaxis/*chemically induced/drug therapy
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Anesthetics, Intravenous/*administration & dosage/adverse effects
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Bronchodilator Agents/therapeutic use
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Dexamethasone/therapeutic use
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Emulsions/chemistry
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Epinephrine/therapeutic use
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Glucocorticoids/therapeutic use
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Humans
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Injections, Intravenous
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Male
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Propofol/*administration & dosage/adverse effects