1.Diabetes mellitus and heart disease.
Anand AMBHORE ; Swee Guan TEO ; Kian Keong POH
Singapore medical journal 2013;54(7):370-quiz 376
Diabetes mellitus is responsible for diverse cardiovascular complications such as accelerated atherosclerosis, increased plaque burden and diffuse coronary lesions. It is also a major risk factor for myocardial infarction, stroke and peripheral vascular disease. Here, we present two cases. The first patient had subtle changes in the ECGs, with severe coronary artery disease requiring coronary artery bypass grafting, while the second had deep T wave inversion in the ECG and was found to have normal coronary arteries and nonischaemic cardiomyopathy. Although ECG failed to show the severity of the disease, it is invaluable as a simple, noninvasive test to aid in diagnosis. Our two cases stress the importance of a high index of suspicion and the low threshold for investigations in the diabetic population.
Aged
;
Biomarkers
;
analysis
;
Combined Modality Therapy
;
Coronary Angiography
;
Coronary Artery Bypass
;
Coronary Stenosis
;
diagnosis
;
therapy
;
Diabetes Complications
;
diagnosis
;
drug therapy
;
surgery
;
Diagnosis, Differential
;
Electrocardiography
;
Humans
;
Male
;
Middle Aged
;
Pulmonary Edema
;
diagnosis
;
therapy
;
Radiography, Thoracic
2.Importance of QT interval in clinical practice.
Anand AMBHORE ; Swee-Guan TEO ; Abdul Razakjr Bin OMAR ; Kian-Keong POH
Singapore medical journal 2014;55(12):607-quiz 612
Long QT interval is an important finding that is often missed by electrocardiogram interpreters. Long QT syndrome (inherited and acquired) is a potentially lethal cardiac channelopathy that is frequently mistaken for epilepsy. We present a case of long QT syndrome with multiple cardiac arrests presenting as syncope and seizures. The long QTc interval was aggravated by hypomagnesaemia and drugs, including clarithromycin and levofloxacin. Multiple drugs can cause prolongation of the QT interval, and all physicians should bear this in mind when prescribing these drugs.
Adult
;
Defibrillators, Implantable
;
Electrocardiography
;
Heart Rate
;
Humans
;
Long QT Syndrome
;
complications
;
congenital
;
diagnosis
;
therapy
;
Male
;
Risk Factors
;
Seizures
;
complications
3.Isolated right ventricle infarction.
Jia Wei WOO ; William KONG ; Anand AMBHORE ; Saurabh RASTOGI ; Kian Keong POH ; Poay Huan LOH
Singapore medical journal 2019;60(3):124-129
We described two patients who were successfully resuscitated from out-of-hospital cardiac arrest. Their ECGs showed ST elevations in V1 and aVR, as well as diffuse ST depression. Their ST elevation in V1 was noted to be greater than in aVR. While one patient was found to have an occlusion of the right ventricular (RV) branch of the right coronary artery, the other was found to have an occlusion of a proximal non-dominant right coronary artery supplying the RV branch. Successful primary percutaneous coronary intervention was performed for each patient with angioplasty and implantation of a drug-eluting stent. Both patients made good physical and neurological recovery.
Adult
;
Angioplasty
;
Angioplasty, Balloon, Coronary
;
Cardiopulmonary Resuscitation
;
Coronary Vessels
;
physiopathology
;
Defibrillators
;
Drug-Eluting Stents
;
Electrocardiography
;
Heart Ventricles
;
physiopathology
;
Hepatitis B
;
complications
;
Humans
;
Male
;
Myocardial Infarction
;
diagnosis
;
physiopathology
;
Out-of-Hospital Cardiac Arrest
;
therapy
;
Percutaneous Coronary Intervention
;
Resuscitation
;
Singapore