No abstract available.
Analgesia, Epidural

A prospective study involved 64 patients (43 men, 21 women) aged from 20 to 62 years with lumbar disc herniation who had operated at Military Hospital 103. These patients were divided into 2 groups. Group 1 received marcaine (0.25%-0.375%) plus fentanyl, group 2 received marcaine (0.35% - 0.5%) alone for lumbar epidural anesthesia. The volume of local anesthetic solutions injected epidurally was calculated based on number of segments that had to block, with dose of 1.5 - 1.6 ml per segment. The results showed that compare with marcaine alone, the combination of marcaine and fentanyl provided better analgesic effect, faster onset and longer duration of action, caused milder hemodynamic changes, decreased the incidence of adverse effects and produced satisfactory post-operative condition
Bupivacaine ; Fentanyl ; Analgesia, Epidural

Three cases of chronic spinal epidural abscess following spinal epidural analgesia are presented. Spinal epidural abscess is a relatively rare infectious disease. It has recently increased in frequency due to the increased use of epidural steroid injections and epidural analgesia. It is very difficult to detect the spinal epidural abscess from its variable symptoms. So, it is important in making a diagnosis of epidural abscess to take into account the previous history of epidural analgesia.
Analgesia, Epidural* ; Communicable Diseases ; Diagnosis ; Epidural Abscess*

BACKGROUND: This study examined the efficacy of patient-controlled epidural analgesia (PCEA) for post-cesarean section pain control and compared the suitability of four different volumes of continuous background infusion (CBI). METHODS: Sixty patients were received 0.125% bupivacaine with 5 g/ml fentanyl by PCEA (2 ml of demand dose and 10 minutes of lockout interval) and CBI. Experimental groups were divided four groups according to the volumes of CBI; 1 ml/hr, 2 ml.hr, 3 ml/hr and 4 ml/hr of CBI during 48 hours postoperatively. RESULTS: Total amount of fentanyl and bupivacaine consumption was significantly higher in 1ml/hr of CBI group than 2 ml/hr of CBI group during first 24 hours, and in 4 ml/hr of CBI group than 1 ml/hr and 3 ml/hr of CBI group during second 24 hours. CBI/maximum hourly demand dose was 15~23%. There is no significant difference between the groups in pain score, side effects and patient's satisfaction. CONCLUSIONS: This study suggests that two or three ml/hr of CBI can provide the most effective postoperative analgesia and the optimal ratio of CBI/maximum hourly demand dose is about 20%.
Analgesia ; Analgesia, Epidural* ; Bupivacaine ; Fentanyl ; Humans

Complex regional pain syndrome (CRPS) is a syndrome of pain and sudomotor or vasomotor instabilities. The perioperative pain management in CRPS patients is very important, as surgery can aggravate preexisting symptoms, especially when performed around the lesion site. Despite the increasing interest in CRPS research, little is known about the optimal perioperative treatment strategy for CRPS patients. Herein, the case of a female CRPS patient, who underwent elective surgery at the lesion site, is reported. As a preemptive analgesia, the patient was satisfactorily managed with two weeks of patient-controlled epidural analgesia, initiated 2 days prior to surgery. The techniques for the prevention of perioperative pain, including preemptive analgesia, as well as its importance, are discussed.
Analgesia ; Analgesia, Epidural ; Female ; Humans ; Pain Management*

BACKGROUND: Clonidine, an alpha-agonist has been postulated to produce analgesia centrally by stimulating the post-synaptic activity of norepinephrine through receptors distinct from opioid receptors and peripherally through a mechanism similar to local anesthetics. It has been suggested that the use of a combination of local anesthetics and clonidine both at lower doses may be effective in providing adequate analgesia at the same time minimizing the deleterious side effects of each drug when used alone at higher doses. The objective of the study was the determination of the minimum dosage of clonidine in combination with bupivacaine necessary for epidural administration that would provide optimal intraoperative and postoperative analgesia with the least occurrence of side effects such as hypotension and bradycardia. METHODOLOGY: One hundred randomly selected, healthy ASA l and 2 gynecologic patients undergoing lower abdominal surgery under epidural anesthesia were given bupivacaine 0.5 percent epidurally compounded with either saline as placebo (Group 1), or clonidine in variable doses: 0.5 ug/kg (Group 2), 1.0 ug/kg (Group 3), and 1.5 ug/kg (Group 4) in a randomized, double-blind fashion. The vital signs were noted every 5 minutes. Analgesia was monitored and recorded using the Visual Analog Scale (VAS), Verbal Rate Scoring and the systemic indicators of pain perception (SBP 30 min Hg increase from baseline or heart rate 20 percent from baseline). A top-up dose of Lidocaine 2 percent was given with systemic indications of pain perception noted intraoperatively or rescue doses of opioids were given when the systemic indications of pain perception were noted at the post anesthesia care unit, upon which data collection was terminated Eighty two patients completed the course of data collection while eighteen were dropped out because of sacral sparing, retraction pain and extension of incision. The statistical tool utilized to test significant differences between the groups was the Kruskal-Wallis Analysis of Variance test and the Partitioned Chi-square test. RESULTS: There is prolongation in the duration of analgesia with incremental increase in clonidine dose. Hypotension occurred even without the addition of clonidine with higher incidence as the dose of clonidine increased. The least side effects occurred with doses of clonidine between 0.5 and 1.0 ug/kg. CONCLUSION: The optimal dosage of clonidine for intraoperative analgesia that would extend to the postoperative period in Filipino women would fall between 0.5 to 1.0 ug/kg. (Author)
Human ; ANALGESIA ; BUPIVACAINE ; CLONIDINE ; ANALGESIA, EPIDURAL

Epidural analgesia provides effective pain control during labor. It however become the subject of controversy in recent years due to the perceived adverse effect on labor and delivery. There has been numerous debates concerning the effects of epidural analgesia on the progress of labor, use of oxytocin, instrumental delivery, cesarean section, neonatal and maternal effects.
ANALGESIA ; ANALGESIA, EPIDURAL ; LABOR PAIN ; CESAREAN SECTION

During pain control by continuous epidural analgesia, the breakage of epidural catheter is a very rare complication. We experienced breakage of epidural catheter in patient of cancer pain during continuous epidural analgesia. We performed epidural catheterization between T12 and L1 level for pain control. After 6 weeks of epidural catheterization, abruptly patient complained severe pain. When we applied negative pressure to catheter by syringe before epidural injection of bolus dose, a few airs were aspirated. We strongly suspected breakage of catheter, and the breakage in 1617 cm from epidural catheter tip was confirmed by normal saline administration via epidural catheter. After new epidural catheter inserted again, patient's pain was controlled by VAS 24 and another complications were not appeared. We must carefully manage the catheter because of complications of epidural catheter.
Analgesia, Epidural* ; Catheterization ; Catheters* ; Humans ; Injections, Epidural ; Syringes

The aim of this investigation was to determine whether epidural analgesia has any effect on the uterine activity. Uterine activity was checked by an intermal tocometer and calculated in uterine activity units (UAU) which were expressed as Montevideo units. Twenty two gravidas who had the term pregnancy in labor without any obstertical complications were selected and epidural analgesia was performed in 17 of these patients. Plain lidocaine was used in 10 of them, lidocaine mixed with epinephrine (200,000:1) was used in another 7 gravidas and 5 gravidas were chosen as a control group. The results were as follows: The uterine actvity of the continuous epidural anesthesia group did not differ from that of the control group. The uterine activity changes were not statistically significant between the plain Iidocaine group and the epinephrine mixed group.
Analgesia, Epidural ; Anesthesia, Epidural* ; Epinephrine ; Humans ; Lidocaine ; Pregnancy ; Uterine Contraction*

The segmental spread of epidural analgesia was measured in seventeen surgical patients aged between 17 and 52 years, and in fourteen patients between 60 and 77 years. The upper level in the young was 6.29(+/-1.56) thoracic vertebra level, but in the elderly was 4 (+/-0.65_ thoracic vertebra level at 20 minutes after epidural injection of 1.5% lidocaine 20 ml. A given volume of solution spreads to 0.9, 1.07, 1.54, 2.29 segments greater upper extent at 5, 10, 15, 20 minutes after epidural injection and 0.57, 1.07 segments greater lower extent at 5, 10 minutes in the elder than young. So with increasing age relatively small amounts of solution are required, to produce the same extent of anesthesia in the young.
Aged* ; Analgesia, Epidural* ; Anesthesia ; Humans ; Injections, Epidural ; Lidocaine ; Spine