Air Pollution ; Health Status ; Humans

OBJECTIVE: To analyze the possible mechanism of Fas mediated apoptosis, investigate the correlation of exercise with apoptosis of cardiomyocytes,skeletal muscle and lymphocytes, and explain the changes of histocyte injury under exercise training from a new level of recognition, so as to provide scientific theoretical evidences for the prevention and treatment of overtraining.DATA SOURCES: A computer-based online search of Springlinker and Pubmed databases was undertaken to identify articles related to Fas mediated apoptosis of cardiomyocytes, skeletal muscle and lymphocytes published in English from January 1994 to December 2004 by using the keywords of "Fas, apoptosis, exercise, skeletal muscle, cardiomyocyte, lymphocyte". Meanwhile, Chinese relevant articles published from January 1994 to December 2004 were searched in the Chinese journal full-text database with the keywords of "apoptosis, exercise, skeletal muscle, cardiomyocyte, lymphocyte" in Chinese.STUDY SELECTION: The data were checked firstly. Inclusive criteria:studies related to Fas mediated apoptosis of cardiomyocytes, skeletal muscle and lymphocytes. The repetitive ones were excluded.DATA EXTRACTION: Totally 58 literatures were collected, 29 repetitive studies were excluded, and the other 29 were accorded with the inclusive criteria.DATA SYNTHESIS: Apoptosis is a gene-controlled process of spontaneous death for cells, and it is the physiological cell death. As a death factor inducing apoptosis, Fas is of important biological significance in regulating apoptosis. The study on exercise and the mechanism of apoptosis signal conduction will explain the changes of histocyte injury under exercise training from a new level of recognition, and provide scientific theoretical evidences for the prevention and treatment of overtraining, Besides,Fas plays an important role in various tumors, diseases of immune system and spinal cord injury.CONCLUSION: The deeper investigation on exercise and Fas mediated apoptosis may disclose the mechanism for the treatment of disease, and introduce new methods of exercise treatment, which undoubtably has important practical significance in accelerating healthy of human being.

Objective To evaluate the efficacy of oxycodone hydrochloride for prevention of fentanylinduced cough during induction of anesthesia in patients.Methods One hundred patients,aged 18-64 yr,weighing 45-74 kg,of ASA physical status Ⅰ or Ⅱ,scheduled for elective surgery under general anesthesia,were randomly divided into 2 groups with 50 cases in each group:control group (group C) and oxycodone hydrochloride group (group O).In C and O groups,normal saline 5 ml and oxycodone hydrochloride injection 0.1 mg/kg (in 5 ml normal saline) were injected,respectively,5 min later fentanyl 3 μg/kg was injected intravenously over 5 s,and 2 min later other drugs for induction of anesthesia were given.The development and intensity of cough were observed within 2 min after fentanyl injection.Results Compared with group C,the incidence of cough was significantly decreased and the intensity of coughing was mitigated in group O.Conclusion Intravenous oxycodone hydrochloride 0.1 mg/kg can decrease the development and intensity of fentanyl-induced cough during induction of anesthesia in patients.

As quantum dots( QDs),an advanced porduct of nanotechnology,have been widely used in bio-medicine due to their unique photoelectric properties. QD safety evaluation has become a hot area of research. So far,some researchers have expressed concern about the neurotoxic potential of QDs because the central nervous system was confirmed to be one of the target organs. Several studies found that QDs could enter the central nervous system by crossing the blood brain barrier and following neural pathways and produce some neurotoxic effects,such as damaging the structure and function of neural cells and impairing synaptic plasticity. The potential toxicity mechanisms could include oxidative stress,inflammation and change of ion channels.

The instance reality of medial equipment combined with the center problem of standardization management on medical equipment stock to discuss the questions of how to manage and what about manage.According to correlated management demand and the fact of medical procurement,from the point of view on frame construction flow to the problem of elementary demand on medical equipment procurement,the stock process of medical instrument,the stock process of medical consumable and the management of purchase invoice etc were analyzed.The beneficial research reference can be provided by the daily management jobs of stock and maintenance,the management question of more refinement and general standardization.

The general principles on maintenance and management of technical specification are discussed. Through summarizing many years maintenance experiences of the hospital or medical institutions technical support department, the beneficial mentalities and referential experiences are provided by standardized and effective management on maintenance of medical equipment, according to the medical technology level of medical equipment management department, the economic efficiency, the size of medical equipment, the quality of maintenance technicians, and service ability as well as the management methods of medical equipment material.

There are many kinds of scaffolds used in the field of tissue engineering, which can be divided into natural biological scaffolds and synthetic scaffolds. This paper summarizes the latest advances of research on scaffolds of skin tissue engineering and review amounts of related literatures on this field. The result shows that natural biological scaffolds can provide a better three-dimensional space for the adhesion and generation of cultured cells. These scaffolds have an extensive application in skin tissue engineering.

Military medical equipment develops rapidly in the 10th five-year-plan,but the low utilization rate still widely remains.One of the deep-seated reasons for this problem is the unreasonable element of the establishment system in military medical organization.This paper suggests reforming the military medical organization establishment system boldly,adjusting the existing power of medical service,concentrating the limited manpower & material resource and strengthening the construction of division hospital so as to fully exert the efficiency of medical equipment and improve the ability of medical service support.

Objective: To study morality and personality of children in single and non-single child family Method:204 children aged 4-14 in single child families were collected 204 children with siblings were sampled matched by age, sex, and education levels of parents and caregivers They composed the matched sample Other 2300 children were also collected in this study including 1626 in single child family and 674 with siblings (random sample) The research instruments included Inventory on Children's Morality, EPQ for children, and Scale of Children's Temperament Parents of children completed these inventory and scales; teachers of children completed the Inventory on Children's Morality Results:In the above two samples, in assessment of morality, parents of single child in family gave lower scores on their children's virtue than parents of multiple children gave on their children But no morality difference was found between single and non-single children when assessed by their teachers In the random sample, more school aged children in single child family had extroversive personality than their counterparts in multiple children family In the matched sample, no difference on introversive-extroversive between single and non-single children was found In both samples, there were more mood-stable and less unstable children in the group of children with siblings; types of Bile-plethora and Bile-melancholic were more frequent in children of single child family Conclusion:Children of single child family are unstable in mood, their morality problems are more obvious in family than in school

Objective To explore the compound azintamide + mosapride application regimen in elderly patients with gastrointestinal diseases and associated dyspepsia in the treatment. Methods 116 cases of elderly patients with gastrointestinal disease associated dyspepsia patients treated in our hospital from April 2016 to April 2017 were randomly divided into observation group and control group, with 58 cases in each group. The observation group was treated with azintamide + mosapride,the control group was treated with mosapride,the two groups were treated for 28 d .The total score of dyspeptic symptoms before and after treatment in two groups was recorded, and the clinical symptoms were evaluated according to the remission rate of symptom scores. The incidence of adverse reactions in the two groups was calculated and compared between the two groups. Results There was no significant difference in total scores of dyspepsia symptoms between two groups before treatment. The total score of the two groups of dyspepsia symptoms decreased in different degrees after the end of the effective course,the observation group was significantly better than the control group (P<0.05). The effective rate of the observation group was 87.9%, which was significantly higher than that of the control group (60.3%) (P<0.05). Conclusion Compound azintamide combined with Mosapride is effective in the treatment of gastrointestinal diseases associated dyspepsia in elderly patients, combination therapy significantly improved in patients with dyspeptic symptoms, improve the quality of life of patients, clinical application of feedback is good, safe and reliable.