Air Pollution ; Health Status ; Humans

As quantum dots( QDs),an advanced porduct of nanotechnology,have been widely used in bio-medicine due to their unique photoelectric properties. QD safety evaluation has become a hot area of research. So far,some researchers have expressed concern about the neurotoxic potential of QDs because the central nervous system was confirmed to be one of the target organs. Several studies found that QDs could enter the central nervous system by crossing the blood brain barrier and following neural pathways and produce some neurotoxic effects,such as damaging the structure and function of neural cells and impairing synaptic plasticity. The potential toxicity mechanisms could include oxidative stress,inflammation and change of ion channels.

Objective To evaluate the efficacy of oxycodone hydrochloride for prevention of fentanylinduced cough during induction of anesthesia in patients.Methods One hundred patients,aged 18-64 yr,weighing 45-74 kg,of ASA physical status Ⅰ or Ⅱ,scheduled for elective surgery under general anesthesia,were randomly divided into 2 groups with 50 cases in each group:control group (group C) and oxycodone hydrochloride group (group O).In C and O groups,normal saline 5 ml and oxycodone hydrochloride injection 0.1 mg/kg (in 5 ml normal saline) were injected,respectively,5 min later fentanyl 3 μg/kg was injected intravenously over 5 s,and 2 min later other drugs for induction of anesthesia were given.The development and intensity of cough were observed within 2 min after fentanyl injection.Results Compared with group C,the incidence of cough was significantly decreased and the intensity of coughing was mitigated in group O.Conclusion Intravenous oxycodone hydrochloride 0.1 mg/kg can decrease the development and intensity of fentanyl-induced cough during induction of anesthesia in patients.

OBJECTIVE:To evaluate the economics of Yindan xintai dropping pills in the treatment of angina pectoris caused by coronary heart disease from societal perspectives. METHODS:Therapy regimens related to Yindan xintai dropping pills and con-trol regimens were selected from published literatures included in database,and the cost of therapy regimens and clinical effect data were extracted from literatures. Contingent evaluation method was used to measure people's willingness-to-pay for angina pectoris treatments. An econometric model was conducted to transfer the effectiveness data to benefit data. The economics of treatment was evaluated depending upon net benefit or incremental net benefit indicator. RESULTS & CONCLUSIONS:When Yindan xintai drop-ping pills is used alone,its net benefit is >0,indicating economical advantage;56 d therapy regimen is better than 28 d therapy. When Yindan xintai dropping pills were combined with glyceryl trinitrate tablet,Isosorbide mononitrate sustained-release tablet, Simvastatin dispersible tablet and other drugs,its incremental net benefit is better than control regimens and has good economics.

[Summary] MicroRNA (miRNA) is a class of endogenous small molecule non‐coding RNAs ,which can inhibit target gene expression via blocking protein translation or inducing mRNA degradation.MicroRNA is also involved in some important physiological processes ,such as cell development , differentiation ,proliferation and apoptosis. Recently ,studies have shown that miRNA plays a role in the development and progression of diabetic retinopathy (DR). This article summarized the research progress of correlation between miRNAs and DR.

Communicable Disease Control ; Humans ; Influenza, Human ; prevention & control ; World Health Organization

Objective To investigate the epidemiological characteristics of imported malaria in Suining City from 2011 to 2016,so as to provide the evidence for improving the surveillance,risk assessment and control measures of imported malaria. Methods The malaria epidemic data in Suining City from 2011 to 2016 were collected from the reporting system,and statisti-cal analyzed. Results Totally 71 malaria cases were reported in Suining City from 2011 to 2016,and they were all imported cases. Sixty cases(84.51％)were imported from Africa. There were cases reported throughout the year,and no obvious seasonal distribution characteristics. The median time from onset to seeing a doctor was 2 days;the median time from seeing a doctor to confirmed diagnosis of malaria was 4 days. Totally 63.38％of the cases were diagnosed of malaria in initially seeing a doctor. For-ty-three cases were diagnosed by county and municipal medical institutions,accounting for 60.56％. All cases were laboratory confirmed cases,and they all received the standardized treatment. Conclusion The imported malaria epidemic situation in Su-ining City is still severe,and it is necessary to strengthen the management of floating population and professional training of med-ical staff so as to prevent the second malaria cases and deaths.

Objective To develop a shoe-cover-style obstacle avoidance device based on gait detection algorithm for the visually impaired.Methods The device was composed of shoes covers and an electric control box.The hardware involved in MSP430F1132 SCM as the control unit,triaxial accelerometer to measure foot acceleration,ultrasonic sensor to detect obstacles and solar battery for power supply.A gait detection algorithm was proposed to implement a foot motion states detection program,and the motion states included static and moving ones.Results The device executed obstacle detection when'the feet were raised and let down,and obstacle detection were stopped in case the feet were kept unmoving,shaking and hanging.The rate for mis-alarm was decreased and the operation procedure was simplified.Conclusion The device behaves well in timeliness,efficiency,mis-alarm,portability,low cost and easy operation,and thus is worthy studying and practical application.

Military medical equipment develops rapidly in the 10th five-year-plan,but the low utilization rate still widely remains.One of the deep-seated reasons for this problem is the unreasonable element of the establishment system in military medical organization.This paper suggests reforming the military medical organization establishment system boldly,adjusting the existing power of medical service,concentrating the limited manpower & material resource and strengthening the construction of division hospital so as to fully exert the efficiency of medical equipment and improve the ability of medical service support.

The instance reality of medial equipment combined with the center problem of standardization management on medical equipment stock to discuss the questions of how to manage and what about manage.According to correlated management demand and the fact of medical procurement,from the point of view on frame construction flow to the problem of elementary demand on medical equipment procurement,the stock process of medical instrument,the stock process of medical consumable and the management of purchase invoice etc were analyzed.The beneficial research reference can be provided by the daily management jobs of stock and maintenance,the management question of more refinement and general standardization.