1.RESEARCH OF THE COMPOSITIONS AND CONTENTS OF FATTY ACIDS IN MEAT AND WASTES IN SCALLOP CHLAMYS FARRERI
Chinese Journal of Marine Drugs 1994;0(03):-
The compositions and contents of fatty acids in the meat and viscera in Chlamys ferreri near Yantai seacoast, Shandong Province were studied in detail. The result showed that the contents of the unsaturated fatty acids in the meat and wastes were 65. 0% and 66. 2%, respectively. Moreover, the contents of the polyunsaturated fatty acids and EPA+DHA were 55. 1% and 37. 5% in the meat, respectively. The contents in the viscera were 48. 8% and 22. 2%, respectively.
2.Adolescent idiopathic scoliosis research progress in abroad
Orthopedic Journal of China 2006;0(15):-
Many controversies and unanswered questions surround AIS(adolescent idiopathic scoliosis),the most difficult one is the absence of information about its aetiopathogenesis.Although bracing has been regarded as the standard of care for patients at a high risk of progression,it has never been subjected to rigorous assessment of either its efficacy or effectiveness.With respect to surgical management,although technology has greatly increased the safety with which we can correct spinal deformity and preserve spinal balance,long-term results of these changing methods of management are absent.Surgery can reduce deformity and prevent further progression;thereby decreasing the risk of future cardiopulmonary compromise,but its role in the prevention of other negative long-term effects of scoliosis is not clear.In this paper we discuss present notions about aetiopathogenesis,natural history,non-operative treatment,and surgery.
3.Effects of repetitive transcranial magnetic stimulation on cognitive function in rats with chronic cerebral hypoperfusion
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(2):95-98
Objective To observe the effects of repetitive transcranial magnetic stimulation (rTMS) on cognitive function in rats with chronic cerebral hypoperfusion.Methods The animal model of chronic cerebral hypoperfusion was established in 30 Sprague-Dawley rats by surgically induced bilateral common caroid artery stenosis,who were then divided into a control group and a treatment group.The rats in the treatment group were administered with 20 Hz rTMS 4 weeks postoperation for 7days.Another 10 rat subject to sham operation served as blank controls.The cognitive function was assessed by Morris water maze (MWM) at the time points of 2nd,3rd,4th and 5th days after ending of the 4 weeks of tretment.The morphologic changes of hippocampus neurons were observed with HE staining.The apoptosis was examined by TUNEL,the expression of Bcl-2 or Bax protein was determined using immnunohistochemistry assay.Results At all the time points the MWM escape latency in the rTMS group was shorter than that in the control group (P < 0.01).The percentage of crossing the corresponding platform during the same time period in platform quadrant in the rTMS group was significant higher than that in the control group (P < 0.01).Compared with the control group,the treatment group demonstrated significantly decreased percentage of neuronal apoptosis (P <0.05),as well as increased expression of Bcl-2 protein (P <0.01) and reduced expression of Bax protein (P < 0.01).Conclusion rTMS can improve the cognitive dysfunction in rats caused by chronic cerebral hypoperfusion,probably through inhibiting neuronal apoptosis in hippocampus region.
5.Expression of CD147, vascular endothelial growth factor C in lung squamous cell carcinoma and adenocarcinoma and their clinical significances
Cancer Research and Clinic 2016;28(5):311-314
Objective To discuss the relationships between expression levels of CD147 and vascular endothelial growth factor C (VEGF-C) in lung squamous cell carcinoma and adenocarcinoma and the clinicopathological features.Methods The expression of CD147 and VEGF-C in 57 lung cancer tissues was detected by immunohistochemical method.Results The positive expression rates of CD147 and VEGF-C in 57 lung cancer tissues were 63.16 % (36/57),66.67 % (38/57) respectively.The expression of CD147 and VEGF-C in lung squamous cell carcinoma and adenocarcinoma had no statistical difference (both P > 0.05).The expression of CD147 and VEGF-C in lung squarnous cell carcinoma and adenocarcinoma had relationship with lymph node metastasis and tumor TNM stage (all P < 0.05),however they had not correlation with the patient' s age,sex,smoking and tumor cell differentiation extent irrelevant (all P > 0.05).The expression of CD147 was related positively with VEGF-C (P < 0.01).Conclusions CD147 and VEGF-C play important roles in the progression and metastasis of lung squamous cell carcinoma and adenocarcinoma,which may have a synergistic effect.The joint detection of CD147 and VEGF-C can be used as a useful prognostic indicator in patients with lung cancer.
6.Analysis of the influence of conbercept intraocular injection to vitrectomy on diabetic retinopathy
Drug Evaluation Research 2017;40(1):104-107
Objective To discuss the influence of conbercept intraocular injection to vitrectomy on diabetic retinopathy.Methods patients (100 cases) with diabetic retinopathy were divided into two groups according to whether use intraocular injection drug or not.The injection group (49 cases) was given conbercept intraocular injection before vitrectomy.The control group (51 cases) was only given vitrectomy.The influence of conbercept intraocular injection to vitrectomy on diabetic retinopathy was evaluated by surgery,prognosis,visual acuity before and after surgery.Results The surgery time of the injection group was shorter than that of the control group (P < 0.05).There were six bleeding cases in the injection group and 20 cases in the control group.The number of bleeding of injection group was shorter than that of the control group (P < 0.05).In addition,the electric coagulation,silicone oil use,iatrogenic macular holes number of injection group was smaller than of that of the control group (P < 0.05).During 1 month follow-up,the number of small bleeding and large bleeding cases of injection group was smaller than of the control group (P < 0.05).There was no statistical significance on vision between two groups.After 1 month surgery,the vision of two groups were increased.And the vision of injection group was significantly higher than that of the control group (P < 0.05).Conclusion In summary,conbercept intraocular injection could help vitrectomy.It could reduce the difficulty of surgery and shorten the surgery time.It could reduce the bleeding symptoms during and after surgery.It could improve the vision of patients.
9.Doppler ultrasound monitoring of complications and callus blood supply at distraction site during distraction osteogenesis
Chinese Journal of Tissue Engineering Research 2015;19(20):3226-3230
BACKGROUND:Evaluation of the newly formed bone at the distraction site by the imaging technologies is the cornerstone for terminating the limb lengthening successfuly.In the early stages of the distraction, the X-ray cannot detect any evidence of new bone formation within the distraction sites, whereas ultrasound can acquire wealth information about new bone and surrounding soft tissues. OBJECTIVE: To explore the application value of Doppler ultrasound in the evaluation of limb lengthening in order to promote its clinical application. METHODS: A computer-based search was performed on the CNKI database and PubMed database for articles related to ultrasound in the evaluation of limb lengthening published from January 1989to October 2014. The keywords of distraction osteogenesis, ultrasonography, external fixation, fracture healing in English and Chinese were used to search the articles by title and abstract. Finaly, a total of 24 articles were included to review. RESULTS AND CONCLUSION: Ultrasound is an effective method to evaluate the limb lengthening in early stage. It can not only detect the formation and maturation of the new calus, but also can evaluate the forming speed and the quality of the new cals. Moreover, ultrasound can be used to evaluate the situation of the soft tissue near the distraction site. Complications associated with the limb lengthening can be observed timely by the ultrasound. Ultrasound is of great significance in the evaluation of distraction osteogenesis.
10.Research progress on the development and functions of tissue barriers using zebrafish model
Acta Laboratorium Animalis Scientia Sinica 2015;23(5):523-528
Zebrafish has been widely used as an important model system in research fields of genetic and develop -mental biology over the past 20 years.Similar to the mammalians and other vertebrate animals , zebrafish also has various tissue barriers.In recent years, more and more important progress of tissue barrier studies have been achieved using ze -brafish as in vivo model, such as blood-brain barrier.These findings contribute to the understanding of the mechanisms of diseases caused by the disorders of physiological barriers .It also helps with the modulation of the permeability of tissue bar-riers for drug delivery .This review summaries recent progress of zebrafish applications in the study of tissue barriers , such as blood-brain barrier, blood-retina barrier, epidermal barrier, etc.