1.DEPRESSIVE AND/OR ANXIETY DISORDER IN PATIENTS WITH AWARENESS DURING GENERAL ANESTHESIA
Modern Hospital 2009;9(7):15-17
Objective To reveal the prevalence of depressive and/or anxiety symptom and disorder in patients with awareness during general anesthesia.Methods 10 patients which had the awareness during general anesthesia were selected into AR group (awareness with recall during general anesthesia group).Face-to-face interviews were used in data collection together with the self-completed HAD scale for depressive and/or anxiety symptom screening.Subjects getting a HAD score of 9 and above were further assessed for depressive and/or anxiety disorders with HAMA scales and HAMD scales.Results The difference of common general state of patients, such as age, weigh and the time during operation were all insignificant between two groups (p>0.05).The rate of patients received general anesthesia only in AR group was higher than that in control group(p<0.05).The prevalence of depressive symptom, the prevalence of depressive or anxiety symptom and the prevalence of depressive and anxiety symptom in AR group were higher than that in control group(p<0.05).The prevalence of depressive disorder, the prevalence of depressive or anxiety disorder and the prevalence of depressive and anxiety disorder in AR group were higher than that in control group too(p<0.05).Conclusion There was high prevalence of depressive and/or anxiety symptom and disorder in patients with recall-awareness during general anesthesia.
2.Correlations between Self-Esteem and Life Satisfaction in Elementary School Students
Chinese Mental Health Journal 2002;0(11):-
Objective:To explore the correlations between self-esteem and life satisfaction in elementary school students. Methods:494 elementary school students were measured with CSES (Children's Self-Esteem Scale) and BMSLSS (Brief Multidimensional Students' Life Satisfaction Scale). Results: (1) There were significant gender and grade differences on self-esteem in elementary school students. Girls got higher scores(Means were 3.8?0.8?3.8?0.9?3.9?0.8)than boys on achievements, discipline and social morality-help(Means were 3.5?0.9?3.2?0.8?3.6?0.9,F=17.2?47.0?16.6, P
3.Life Satisfaction between Urban and Rural Middle School Students
Chinese Mental Health Journal 2002;0(10):-
Objective: To compare the differences between urban and rural middle school students on life satisfaction. Methods: 1152 urban and rural middle school students were measured by Multidimensional Students'Life Satisfaction Scale ( MSLSS - CV) . Results: ( 1 ) The urban students had higher scores than their rural counterparts on all the satisfaction dimensions ( mean value differences = 0. 2 - 0. 4. For example, the family satisfaction of urban and rural students were 4. 6?1. 0, 4. 2?1.0 respectively, mean value difference =0. 4; the serf satisfaction of urban and rural students were 4. 6?0. 7 , 4. 4?0. 7 respectively, mean value difference = 0. 2 ) . ( 2 ) The mean values rank (from high to low) of the five dimensions on the satisfaction was family, self, friend, school and living environment in urban students. The mean values rank (from high to low) of the five dimensions on the satisfaction was self, family, friend, school and living environment in rural students. (3 ) The difference between city and countryside had higher explained percentage than popularity on all the satisfaction dimensions. The percents were as follows: 5% , 10% , 4% , 6% , 17% , 11%. Conclusion: There were significant differences on life satisfaction between urban and rural middle school students.
4.Study on The Effects of Chronic Renal Failure on Hearing and Its Mechanism
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To observe the effects of chronic renal failure (CRF)on hearing and investigate its mechanism.[Methods] Twenty-nine male wistar rats were randomly divided into four groups:Ⅰthe normal rats as control for 12 days (n=6); Ⅱrats given adenine(ig) for 12 days (n=8); Ⅲthe normal rats as control for 24 days (n=6);Ⅳ rats given adenine(ig) for 24 days(n=9). The rat model of CRF was produced by being perfused of adenine [300mg/kg]for 12d and 24d. Brain-stem auditory evoked potential(BAEP) was utilized to evaluate the auditory function and renal tissue morphology was observed; Serum sampling was used to determine the content of Cr, BuN. The expression of NOSⅡin the cochlear was measured by immunohistochemical technique.[Results] After adenine given for 12d or 24d, the Cr and BuN were in significant higher level than that in control group. The BAEP thresholds were gradually higher than that in control group, the BAEP delitescence prolonged. Light microscopic observation of renal tissue showed that the degree of fibrosis was gradually higher. Data of immune histochemistry about the cochlear tissue showed that the expressions of NOSⅡ were feebly positive in the cochlear vassal texture, inner-outer hairy cell and helical-ganglion cell, and following functional damage of the kidney, their expressions reinforced gradually, amongst which strongest expression was vassal texture, the next helical-ganglion cell, the last inner-outer hairy cell.[Conclusion]CRF can result in deafness. It is likely concerned with toxic effects of the metabolizable substance, the metabolizable dysfunction of the electrolyte, shortage of trace elements, etc. One of the important mechanisms of the effects of CRF on hearing is the toxic damage of NO to cochlea.
5.Research on medical data mining and its applications.
Journal of Biomedical Engineering 2014;31(5):1182-1186
With the development of computer technology, medical data has developed from traditional paper pattern into electronic mode, which could effectively promote the medical development. This paper at first presents the status and characteristics of medical data mining. Then, it discusses the critical method of medical data mining in classification, clustering and prediction, respectively. The paper focuses on the application and assessment of five algorithms which are designed for medical data mining, including decision tree, cluster analysis, association rule, intelligent algorithm and the mix algorithm. Finally, this paper outlooks the data mining application in medical domain.
Algorithms
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Cluster Analysis
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Data Mining
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Decision Trees
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Medical Informatics
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Software
6.Identification and treatment of delirium in elderly patients
Chinese Journal of Geriatrics 2012;31(5):445-446
Delirium is a common disorder in aged people.Although it is in poor prognosis,delirium still has been under-recognized and inappropriately evaluated and treated.The clinical aspects of delirium on epidemiology,diagnosis,risk and precipitating factors,prevention and treatment were introduced in this paper.
7.Anti-UACA autoantibody in thyroid-associated ophthalmopathy
Chinese Journal of Endocrinology and Metabolism 2012;28(5):402-403
Serum anti-uveal autoantigen with coiled coil domains and ankyrin repeats (UACA) antibody titer was measured using ELISA in 32 patients with thyroid-associated ophthalmopathy ( TAO ) and 20 patients with Graves' disease (GD) without ophthalmopathy.The level of anti-UACA antibody in TAO group was higher than that in GD group [ (225.91 ± 144.21 vs 187.42 ± 46.77 ) pg/ml,P<0.05 ],and especially higher in patients with ocular myopathy [ (254.35 ± 168.29 ) pg/ml ].It seems that anti-UACA antibody is the sensitive clinical marker of ocular myopathy in TAO patients.
8.Correlation and regression analysis on nurse's job burnout, self-efficacy and work environment
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(6):549-551
ObjectiveTo investigate the status of job burnout of clinical nurses,and to analyze its relationship with self-efficacy and the environmental factors.MethodsMaslach Burnout Inventory,General Self-Efficacy Scale,Nursing Work Index-Revised and Nurses'Job Stressor Scale were used to investigate 239 clinical nurses from 2 tertiary first-class hospitals of Lianyungang City.Correlation and regression analysis were used to analyze the relationship between all the dimensions of nurse burnout,self-efficacy,professional nursing practice environment and job stressor.ResultsThe scores of emotional exhaustion and depersonalization were ( 23.95 ± 11.11 ) and (7.90 ± 6.58 ) respectively,indicating medium level of burnout.The score of decreased personal accomplishment was reverse coded,and the score was ( 27.51 ± 10.96),indicating a high level of burnout.Both work environment and self-efficacy were related to job burnout (P < 0.05 or P < 0.01 ).Environment played bigger roles in influencing emotional exhaustion and depersonalization,and self-efficacy influenced personal accomplishment more significantly.ConclusionMore attention should be paid to the improvement of nurses' self-efficacy and work environment in order ot reduce nurses'job burnout.
9.Role of combination of PET-CT and tumor markers in assessment of response in advanced non-small cell lung cancer after chemotherapy and radiotherapy
Journal of International Oncology 2011;38(6):453-456
After chemoradiation therapy, tumor tissue metabolism changes earlier than its shape in advanced non-small cell lung cancr (NSCLC). Therefore, Positron emission tomography-computed tomography (PET-CT) can early assess the therapeutic efficacy and prognosis. But PET-CT might bring up some false negative or false positive outcome, while combined with the tumor markers, more accurate assessments of therapeutic efficiency and prognosis could be made for advanced(NSCLC).
10.Effects of vascular endothelial growth factor from pulmonary stromal cells on differentiation and function of dendritic cells
Chinese Journal of Geriatrics 2011;30(12):1043-1046
Objective To observe the effects of vascular endothelial growth factor(VEGF)from pulmonary stromal cells on differentiation and function of mature dendritic cells (mDC) and the immune tolerance. Methods Co-culture system of murine pulmonary stroma cells (MPSC)/mDC was established as control group,and VEGF-Ab add-on treatment to co-culture cells as experimental group.Cytokines secreted from pulmonary stroma cells were detected by RT-PCR.The expression of cellular phenotype and ability of the mDC-induced T cells reproductive activity were detected by flow cytometry and CCK-8,respectively.Results CD86 expression of VEGF-Ab group was higher than of control group (P < 0.05).There was no difference in the ability of mDC-induced T cells reproductive activity between the two groups(P>0.05).Conclusions VEGF might be involved in the regulation of immune tolerance by reducing expression of CD86 in dendritic cells.