Epistaxis is a common otorhinolaryngological emergency with complex etiological factors and varied clinical manifestations. The key to epistaxis treatment is accurate diagnosis and adequate hemostasis. Electrocoagulation is a reliable, safe and effective treatment for epistaxis. However, there are still several deficiencies in application of the commonly used electrocoagulation surgical products. This paper introduces a new type of radiofrequency head incorporating the dynamic circulatory functions of drip, irrigation, hemostasis and aspiration. We aim to achieve noninvasive, effective and accurate hemostasis in the treatment of epistaxis or nasal sinus surgery.
Humans ; Epistaxis/surgery* ; Electrocoagulation ; Treatment Outcome ; Paranasal Sinuses

Objective:To examine the expression of TRAF 6 in ovarian carcinomas ,discuss the relation between expression level and clinical characteristics of ovarian carcinomas and study the clinical significance .Methods: Specimens from 102 patients with ovarian carcinomas managed in our hospital between Augest 2001 and December 2009 were included in this study .Immunohistochemical staining was used to detect the expression of TRAF 6 in ovarian carcinomas and normal tissues .All the specimens were confirmed by pa-thology for ovarian carcinomas and normal tissues by HE staining .Then, the correlation between the expression and clinical characteristics of patients was analyzed .Furthermore ,survival analyses were performed according to the Kaplan-Meier method.Results:The positive expression rate of TRAF 6 in ovarian carcinomas and normal tissues was 68.6% and 20.5%, respectively.TRAF6 expression was significantly associated with tumor stage and distant metastasis ( P<0.05 ) .According to the survival analysis of 102 ovarian carcinomas patients ,cases in the TRAF6 low-expression group showed poorer overall survival rate when compared with low -expression group ( P<0.001 ) .Conclusion: These results indicate that the expression of TRAF 6 was closely related with in the progression of ovarian carcinomas and may have clinical utility in the prediction of prognosis of ovarian carcinomas .

Objective To observe the clinical efficacy of acupuncture by selecting points from the Lung and Stomach Meridians based on the theory of accumulation in stomach and connection with lung in treating post-infectious cough.Method Ninety patients with post-infectious cough were randomized into treatment group 1, treatment group 2, and a control group. Treatment group 1 was intervened by acupuncture at points from the Lung and Stomach Meridians, treatment group 2 was by puncturing points from the Lung Meridian, and the control group was by oral administration of Compound Methoxyphenamine Capsule. Leicester Cough Questionnaire (LCQ) was adopted for observation before and after intervention, and the symptom and clinical efficacies were compared between the groups.Result The total effective rate was 90.0% in treatment group 1, versus 83.3% in treatment group 2, and 80.0% in the control group. The total effective rate of treatment group 1 was significantly different from that in treatment group 2 and the control group (P<0.05). Regarding cough during the daytime, the total effective rate was 93.3% in treatment group 1, versus 83.3% in treatment group 2 and 76.7% in the control group. The total effective rate in treatment group 1 for cough during the daytime was significantly different from that in treatment group 2 and the control group, and the total effective rate in treatment group 2 was significantly different from that in the control group (P<0.05). For cough at night, the total effective rate in treatment group 1 was 86.7%, versus 80.0% in treatment group 2 and 80.0% in the control group. The total effective rate in treatment group 1 for cough at night was significantly different from that in treatment group 2 and the control group (P<0.05). The LCQ score in treatment group 1 was markedly different from that in treatment group 2 and the control group (P<0.05).Conclusion Acupuncture based on lung-stomach theory is an effective approach in treating post-infectious cough, and this method has an advantage of general regulation.

Obejective To analyze the related papers on nursing competency in China from 2004 to2014,and to learn the current status and developing trends of nursing competency,so as to provide reference for further research and development of nursing competency.Methods All literature related to nursing competency from 2004 to 2014 were searched in the China National Knowledge Infrastructure(CNKI),VIP Database for Chinese Technical Periodicals (VIP),and Wanfang database.Bibliometric analysis methods were used to analyze the distribution time,area,journal distribution and research categories by using Microsoft Excel.Results Totally 199 articles related to nursing competency were collected and the number of publications increased in recent years.About 78.89％ (157/199) papers were published in the statistical source journal and 34.17％ (68/199) papers were focused on survey research about nursing competency.Conclusions Nursing competency have been paid more attention to,but the quality of the literature still need to be improved.

Objective To observe the biological characteristics and analyse primary therapeutic response of acute erythroid leukemia.Methods The data of 28 patients primarily diagnosed as acute erythroid leukemia were analyzed.The patients were divided into with muhilineage dysplasia group and without muhilineage dysplasia group,and the morphology,immunology,cytogenetics and molecular biology characteristics and the complete remission rate of the first induction therapy were compared.Results There were 14 cases(50％)with muhilineage dysplasia,which involved in two lineage or trilineage.In 6 cases by flow cytometry,the myeloid blast immunophenotypes were common expressed.In 8 cases detected by karyotype analysis,5 cases were chromosomal abnormal,including 4 cases were complex chromosomal abnormal,1 case was trisomy 8.In 4 cases underwent WT1 detection,all of them were positive.The complete remission rate of the first induction therapy was 39.29％(11/28),the ratein the multilineage dysplasia group was 35.71％(5/14),and the ratein without multilineage dysplasia group was 42.86％(6/14),the difference had no statistical significance(P＞0.05).The complete remission rate of the complex chromosome group was 25.00％(1/4),the intermediate prognostic group was 50.00％(2/4).Conclusions Acute erythroid leukemia had special biological features different from other subtype AML:accompanyed with high frequency of multilineage dysplasia.The abnormality of karyotype were high,and it was often complex karyotype involved with chromosome 5 and/or chromosome 7,which had a low complete remission rate.The complete remission rate of chemotherapy was low,treatment effect was poor.

Objective To explore the role of procalcitonin (PCT) in diagnosis and antibiotics therapy of community acquired pneumonia (CAP). Methods A total of 296 patients with CAP and 221 patients with other diseases were included. PCT levels between CAP patients and non-CAP patients, aged and non-aged CAP patients were analyzed. SPSS19.0 was used to make ROC, and the maximum Youden index to determine the optimal cutoff value, the corresponding sensitivity (SEN) and specificity (SPE). Results PCT levels in CAP patients were significantly higher than those in non-CAP (P<0.05). The diagnostic value of PCT in CAP was as follows: the area under the curve (AUC) was 0.67, the optimal cutoff value 0.055 ng/mL and the SEN and SPE were 0.55 and 0.77 respectively. For aged CAP patients, the values were 0.63, 0.055 ng/mL, 0.53 and 0.73 respectively and for non-aged CAP patients, the values were 0.73, 0.085 ng/mL, 0.53 and 0.90 respectively. The days of treatment in PCT-guided antibiotics therapy group were greatly less than those in clinical and radiology-guided antibiotics therapy (P<0.05), while there was no difference on relapse (P>0.05). Conclusion PCT has a high value in diagnosis and antibiotics therapy of CAP.

0.05); awake time were (10.08?5.67) min and (15.50?3.47) min (P

Cause-effect deduction is the basis of both natural and social sciences. Both wealthy knowledge and logical design are essential in obtaining the true causality among medical studies. Though association analysis provides important information for cause-effect deduction, it does not mean causality itself. Before the existence of the causality between two variables being identified, rigorous criteria must be followed. A number of indexes, such as the significance and the degree of the association, the dose-response relationship, the biology-based possibility, as well as the consistency and specificity, all should be examined very carefully. Clear verifiable hypotheses, rational selection of subjects, reliable experimental methods, appropriate statistical analysis and correct logical deductions, all are the integral parts that finally constitute a faithful deduction.

Proteomics is a new research area of the post-genomic era. Oncoproteomics is an important branch of it.Here we discuss the investigative outcome of thyroid oncoproteomics in recent years,such as specific tumor biomarkers and antineoplastic drug.

micro RNA (miRNA) is the fragment of non-coding small RNAs and consists of 21-25 ribonucleotide.It can regulated gene expression by either binding to or regulating the translation process of some specific mRNA. This paper summarized the characteristics of miRNA, as well as its production, mechanism of action and functions.