1.The research on humanities education of medical postgraduates
Chinese Journal of Medical Education Research 2011;10(6):690-692
This article found that the actual situation about humanities education of medical postgraduates is not optimistic through investigation of the situation on humanities education of the postgraduates in Zunyi Medical College. Some prominent problems existed. This article also proposed some practical suggestions to solve the problems based on the analysis of this phenomenon, so as to improve the humanities education of medical postgraduates and cultivate postgraduates to be medical workers with full humanistic care.
5.Research progress on the topical use of triamcinolone in the treatment of oral mucosal diseases
Journal of Practical Stomatology 2015;(2):278-281
A total of 21 papers about topical use of triamcinolone in the treatment of oral diseases were retrieved.1 7 of the 21 papers were about the treatment of oral lichen planus,3 were about recurrent aphthous ulcer and 1 was about Behcet's Syndrome.Topical use of triamcin-olone,either used alone or combined with other drugs,was effective in the treatment of oral lichen planus,recurrent aphthous ulcer and Beh-cet's Syndrome.No adverse drug reaction happened when triamcinolone was used in the patients after a short time application,while it hap-pened in the patients after prolonged-use.It may be also effective in the treatment of other allergy or immune dysfunction related oral mucosal diseases,of which more research should be carried out.
6.Heat shock protein and cardioprotection
Journal of Medical Postgraduates 2003;0(09):-
The defense mechinism of heat shock protein(HSP)acting as moleculars chaperons requires heat shock transcription factors as the primary mediators of the heat shock response.Increased expression of HSP may protect the heart.Overexpression of HSP can inhibit cardiomyocyte apoptosis,protect the integrity of the microtubules and the actin cytoskeleton in cardiac myocytes and endothelial cells exposed to ischemia,participate in the folding and activation of protein kinases and transcription factors such as HIF-1? and HSF1,bind to endothelial nitric oxide synthase(Enos) and stimulate its activity,and downregulate cytokine production.Hence,it is of benefit to efficiently elevate HSP expression in myocardium using pharmacological and/or gene therapy procedures without any adverse effect.
7.Study of the correlation between abnormal lipid metabolism and the severity of coronary artery lesions
Chinese Journal of Interventional Cardiology 1993;0(02):-
Objective To investigate the correlation between abnormal lipid metabolism and coronary artery lesions. Methods Two hundred and sixty seven patients were devided into the control group ( n =101) and the coronary heart disease (CHD) group ( n =166), which included single vessel lesion ( n =54), double vessel lesions ( n =68) and triple vessel lesions ( n =44) according to coronary angiography. At the same time the lipid components were examined and the ralationship between serum lipid level and coronary artery lesions were analysed. Results Compared with the control, the total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) level were significantly elevated while but high density lipoprotein cholesterol (HDL-C) was lowered in the CHD group. The severity of coronary lesions was increased with the elevation of TC, LDL-C, apolipoproteinB (ApoB), TC/HDL-C, LDL-C/HDL-C, and the reduction of HDL-C. There were significant differences in terms of lipid level beteewn the CHD group and the control. The analysis showed that TC/HDL-C and LDL-C/HDL-C were most directly correlated with the coronary artery lesions in the CHD group. Conclusion The results suggest that the severity of coronary artery lesions correlated with abnormal lipid metabolism, and LDL-C/HDL-C, TC/HDL-C are better indicators than other lipid components.
8.Thought on development of minimally invasive gastrointestinal surgery in China.
Chinese Journal of Gastrointestinal Surgery 2012;15(8):765-767
Laparoscopic surgery for gastrointestinal diseases had a remarkable progress in the past 20 years. Laparoscopic surgery for colon cancer is adopted worldwide by increasingly surgeons based on the evidence from randomized controlled studies. Minimally invasive surgery is also adopted as alternative procedure for early gastric cancer. The standardization and spreading of the minimally invasive technique for gastrointestinal surgery is also being implemented efficiently in China. However, how to innovate the new technique and improve the new instrumentation for minimally invasive surgery is still a problem which we have to confront in the current situation. But we believe that with the great efforts of gastrointestinal surgeons, the widespread adoption of minimally invasive gastrointestinal surgery would surely take place in the near future.
China
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Gastrointestinal Tract
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surgery
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Humans
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Laparoscopy
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methods
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Minimally Invasive Surgical Procedures
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methods
9.A citation analysis of Chinese Journal of Geriatrics from 1999 to 2004
Chinese Journal of Geriatrics 2000;0(06):-
Objective To evaluate the academic quality and characteristics of edition of the Chinese Journal of Geriatrics. Methods Within the database of Chinese Medical Citation Index(CMCI), the citation analysis was used to analyze the number and its distribution of the cited original articles published in the Journal 1999-2004. Results The average freguency for a single article cited by other researchers was 2.82, and there were more articles cited than other journals. The authors of these articles were distributed in the 30 province and municipalities, among which Beijing, Guangdong Province, Shanghai were in the front of Geriatrics research. There were 514 cited journals, and self-citing rate was 6.07%. Conclusions The Chinese Journal of Geriatrics has published high quality articles, and has its own edition characteristics to keep its steady level of research. It is one of the most important information resources for the geriatrics researchers and one of the most important medical journal.
10.Preparation of Tretinoin Liposome by Calcium Acetate Gradient Method
China Pharmacy 2001;0(08):-
OBJECTIVE:To evaluate the feasibility of preparing tretinoin liposome by calcium acetate gradient method and to compare this method with the microfilm and the antiphase evaporation method.METHODS:Tretinoin liposome was pre-pared by microfilm method,antiphase evaporation method and calcium acetate gradient method,respectively.Sephadex G-50was used for isolation and ultraviolet spectrophotometry was utilized to determine the entrapped efficiency and grain size of liposomal tretinoin.Electronmicroscope was applied to observe the shape of tretinoin liposome.RESULTS:The calcium ac-etate gradient technology achieved the highest entrapped efficiency of90.48%.The liposomes had perfect shape with the mean diameter of35.8nm and kept stable in quality at4℃for3months.CONCLUSION:The liposome with high entrapped effi-ciency could be prepared by calcium acetate gradient method,and the method is feasible.